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Source: Neurotoxicology
Drug: Amphetamine
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Total 1 results found since Jan 2013.
Amphetamine makes caudate tissue more susceptible to oxygen and glucose deprivation.
Abstract
Amphetamine is being investigated to reduce morbidity following stroke. However, the medicinal use of amphetamine is complicated because this drug is addictive, cardiotoxic, and can be neurotoxic. Thus, further research into the safety of giving amphetamine to stroke patients is required. Here, we examine whether prior treatment with amphetamine has any effect on oxygen-glucose deprivation (OGD)-evoked transmitter efflux and mitochondrial function. To circumvent the well-documented cardiovascular effects of amphetamine we have used rat brain slices. Brain slices were exposed to 30μM of amphetamine for 10...
Source: Neurotoxicology - June 17, 2013 Category: Neurology Authors: Tana A, Davidson C Tags: Neurotoxicology Source Type: research
