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Potential specific immunological indicators for stroke associated infection are partly modulated by sympathetic pathway activation.
CONCLUSION: IL-6, IL-10 and HLA-DR are good candidate biomarkers for SAI. The activation of the sympathetic pathway could partly account for the specific immunological alterations found in SAI patients including HLA-DR decrease and IL-10 increase, which both could be reversed by propranolol. However, the mechanism underlying IL-6 increase still needs further exploration. PMID: 27409177 [PubMed - as supplied by publisher]
Source: Oncotarget - July 15, 2016 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

Beta-blockers in Pediatric Hypertrophic Cardiomyopathies.
Conclusions: Beta-blocker therapy is without doubt the treatment of choice for patients with heart failure caused by hypertrophic cardiomyopathy, but the dose needs to carefully titrated on an individual basis for maximum benefit, and the dose required is surprisingly large in infants with heart failure due to hypertrophic cardiomyopathy. PMID: 25198737 [PubMed - as supplied by publisher]
Source: Reviews on Recent Clinical Trials - September 8, 2014 Category: Cancer & Oncology Authors: Ostman-Smith I Tags: Rev Recent Clin Trials Source Type: research