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Magnetic Resonance Imaging Measurement of Transmission of Arterial Pulsation to the Brain on Propranolol Versus Amlodipine Brief Reports
Conclusions— We piloted a novel method of assessment of arterial pulsatility with concurrent high-frequency blood-oxygen level dependent magnetic resonance imaging and noninvasive blood pressure monitoring. This method was able to identify greater transmission of aortic pulsation on propranolol than amlodipine, which warrants further investigation.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Webb, A. J. S., Rothwell, P. M. Tags: Hemodynamics, Magnetic Resonance Imaging (MRI), Vascular Disease Brief Reports Source Type: research

Hypersomnia and Reduction in Essential Tremor after Bilateral Subthalamic Ischemic Stroke (P4.285)
Conclusions:Prevalence of hypersomnia among stroke patients ranges from 1.1 to 27[percnt].A reduction in the activity of arousal systems underlies most forms of post stroke hypersomnia.Multiple changes like reduction in the amount of NREM sleep, sleep time, sleep spindles, REM sleep ( in occipital strokes ) were also described depending on the location of the stroke. Thalamic and brainstem strokes can present with pathological EEG patterns like alpha coma.Along with bilateral thalamic strokes, strokes in thalamo-mesencephalic regions, upper pons and medial pontomedullary lesions can cause marked hypersomnia. Cortical and s...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Pesala, S., Nalleballe, K., Bollu, P. Tags: Parasomnias and Hypersomnias Source Type: research

Low-dose propranolol and exercise capacity in postural tachycardia syndrome: A randomized study
Conclusions: These findings suggest that nonselective β-blockade with propranolol, when used at the low doses frequently used for treatment of POTS, may provide a modest beneficial effect to improve heart rate control and exercise capacity. Classification of evidence: This study provides Class II evidence that a single low dose of propranolol (20 mg) as compared with placebo is useful in increasing maximum exercise capacity measured 1 hour after medication.
Source: Neurology - May 20, 2013 Category: Neurology Authors: Arnold, A. C., Okamoto, L. E., Diedrich, A., Paranjape, S. Y., Raj, S. R., Biaggioni, I., Gamboa, A. Tags: Autonomic diseases, Cardiac, Class II ARTICLE Source Type: research