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The incidence of medium vessel occlusions: a population-based study
ConclusionAs the only stroke center in Olmsted County, we have been able to estimate the incidence of ischemic stroke due to MeVO. While the incidence of MeVOs is less than both large and small vessel occlusions, they still represent a significant proportion of strokes with significant morbidity and mortality that would benefit from further studies in both acute intervention and prevention.
Source: Frontiers in Neurology - July 27, 2023 Category: Neurology Source Type: research

Lifelong cerebrovascular disease burden among CADASIL patients: analysis from a global health research network
DiscussionEarly screening and targeted treatment strategies are warranted to help CADASIL patients with symptom management and risk mitigation.
Source: Frontiers in Neurology - July 14, 2023 Category: Neurology Source Type: research

Trends in deaths and disability-adjusted life-years of stroke attributable to high body-mass index worldwide, 1990 –2019
ConclusionA range of indicators for the global burden of stroke attributable to HBMI have been on the rise for the past three decades. Tremendous efforts worldwide should be in place to control and treat stroke attributable to HBMI, especially in regions with high-middle and middle SDIs and among middle-aged and aged populations.
Source: Frontiers in Neurology - June 30, 2023 Category: Neurology Source Type: research

Seasonal variation in the incidence of primary intracerebral hemorrhage: a 16-year nationwide analysis
ConclusionUnlike AIS, ICH incidence is consistently higher in colder quarters, underscoring the need for evaluation and prevention of factors driving seasonal variations in ICH incidence.
Source: Frontiers in Neurology - June 29, 2023 Category: Neurology Source Type: research

Associations between homocysteine and B vitamins and stroke: a cross-sectional study
ConclusionNon-linear associations of plasma Hcy and B vitamins levels with stroke prevalence were found in American adults. These associations may have an implication that higher plasma Hcy levels should be reduced, and plasma vitamin B6, vitamin B12 and folate levels should be moderately improved in stroke prevention. Future studies are needed to verify the causality of these associations and elucidate the underlying mechanisms.
Source: Frontiers in Neurology - June 29, 2023 Category: Neurology Source Type: research

Stroke nurse navigator utilization reduces unplanned 30-day readmission in stroke patients treated with thrombolysis
ConclusionThe utilization of a stroke nurse navigator team reduced unplanned 30-day readmissions in stroke patients treated with thrombolysis. Further studies are warranted to determine the extent of the results of stroke patients not treated with thrombolysis and to better understand the relationship between resource utilization during the transition period from discharge and quality outcomes in stroke.
Source: Frontiers in Neurology - June 15, 2023 Category: Neurology Source Type: research

Association between hysterectomy status and stroke risk and cause-specific and all-cause mortality: evidence from the 2005 –2018 National Health and Nutrition Examination Survey
ConclusionOur study found a significant association between hysterectomy and stroke, even after adjusting for other factors that could impact risk, such as the American Heart Association (AHA)'s Life's Simple 7 cardiovascular health score and variables of age, ethnicity, marital status, income, education, and depression severity.
Source: Frontiers in Neurology - May 18, 2023 Category: Neurology Source Type: research

EMAGINE –Study protocol of a randomized controlled trial for determining the efficacy of a frequency tuned electromagnetic field treatment in facilitating recovery within the subacute phase following ischemic stroke
Stroke is a leading cause of disability with limited effective interventions that improve recovery in the subacute phase. This protocol aims to evaluate the safety and efficacy of a non-invasive, extremely low-frequency, low-intensity, frequency-tuned electromagnetic field treatment [Electromagnetic Network Targeting Field (ENTF) therapy] in reducing disability and promoting recovery in people with subacute ischemic stroke (IS) with moderate-severe disability and upper extremity (UE) motor impairment. Following a sample-size adaptive design with a single interim analysis, at least 150 and up to 344 participants will be rec...
Source: Frontiers in Neurology - May 5, 2023 Category: Neurology Source Type: research

Bibliometric analysis of stroke and quality of life
ConclusionA bibliometric analysis of stroke and quality of life over the last 23  years provides future research directions.
Source: Frontiers in Neurology - April 11, 2023 Category: Neurology Source Type: research

Global research trends on COVID-19 and stroke: A bibliometric analysis
ConclusionOur bibliometric analysis provides a comprehensive overview of the current state of research on COVID-19 and stroke and highlights key areas of focus in the field. Optimizing the treatment of COVID-19-infected stroke patients and elucidating the underlying pathogenic mechanisms of COVID-19 and stroke co-morbidity are key areas of future research that will be beneficial in improving the prognosis of stroke patients during the ongoing COVID-19 epidemic.
Source: Frontiers in Neurology - April 3, 2023 Category: Neurology Source Type: research

The effects of racism and resilience on Black stroke- survivor quality of life: Study protocol and rationale for a mixed-methods approach
This study aims to examine the effects of experiences of racism and resilience on Black SS QoL during early stroke recovery. This article presents the study protocol.Methods and analysesThis will be a prospective observational mixed-methods study. Black community-dwelling adults who are within 4 weeks of a stroke will be eligible for inclusion. Baseline measures will include the exposure variables of experiences of racism and resilience. Covariates measured at baseline include sociodemographic variables (age, sex, marital status, education, income, health insurance, employment status, number of people in household, residen...
Source: Frontiers in Neurology - August 10, 2022 Category: Neurology Source Type: research

Lessons Learned From the Historical Trends on Thrombolysis Use for Acute Ischemic Stroke Among Medicare Beneficiaries in the United States
ConclusionsBetween 2007 and 2014, the frequency of IVT for patients with acute ischemic stroke increased substantially, though differences persisted in the form of less frequent treatment associated with certain characteristics. These findings can inform ongoing efforts to optimize the delivery of IVT to all AIS patients nationwide.
Source: Frontiers in Neurology - March 4, 2022 Category: Neurology Source Type: research

Academic Performance of Children With Sickle Cell Disease in the United States: A Meta-Analysis
Conclusion: Students with sickle cell disease demonstrate notable academic difficulties and are at high risk for grade retainment. Development of academic interventions and increased access to school support services are needed for this vulnerable population.Systematic Review Registration:https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020179062.
Source: Frontiers in Neurology - December 13, 2021 Category: Neurology Source Type: research

Cerebrovascular Risk Profiles in a Saudi Arabian Cohort of Young Stroke Patients
Conclusion: Cerebrovascular risk profiles and stroke etiologies in our cohort of young stroke patients differ from those of previous cohorts, suggesting the need for tailored prevention strategies that take into account local epidemiological data on cerebrovascular health.
Source: Frontiers in Neurology - November 12, 2021 Category: Neurology Source Type: research

End-of-Life Care Decision-Making in Stroke
Stroke is one of the leading causes of death and long-term disability in the United States. Though advances in interventions have improved patient survival after stroke, prognostication of long-term functional outcomes remains challenging, thereby complicating discussions of treatment goals. Stroke patients who require intensive care unit care often do not have the capacity themselves to participate in decision making processes, a fact that further complicates potential end-of-life care discussions after the immediate post-stroke period. Establishing clear, consistent communication with surrogates through shared decision-m...
Source: Frontiers in Neurology - September 28, 2021 Category: Neurology Source Type: research

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