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Total 1461 results found since Jan 2013.

Influence of a Comorbid Diagnosis of Seizure on 30-Day Readmission Rates Following Hospitalization for an Index Stroke
Objective: To examine the association of a comorbid seizure diagnosis with early hospital readmission rates following an index hospitalization for stroke in the United States. Methods: Retrospective analysis of the 2014 National Readmission Database. The study population included adult patients (age>18 years old) with stroke, identified using the International Classification of Disease Ninth Revision, Clinical Modification (ICD-9-CM) codes 433.X1, 434.X1, and 436 for ischemic stroke as well as 430, 431, 432.0, 432.1, and 432.9 for hemorrhagic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - November 25, 2019 Category: Neurology Authors: Alain Lekoubou, Kinfe G Bishu, Bruce Ovbiagele Source Type: research

Educational Intervention in the Emergency Department to Address Disparities in Stroke Knowledge
In the United States, Black individuals have higher stroke incidence and mortality when compared to white individuals and are also at risk of having lower stroke knowledge and awareness. With the need to implement focused interventions to decrease stroke disparities, the objective of this study is to evaluate the feasibility and efficacy of an emergency department-based educational intervention aimed at increasing stroke awareness and preparedness among a disproportionately high-risk group.
Source: Journal of Stroke and Cerebrovascular Diseases - March 22, 2022 Category: Neurology Authors: Erin F. Shufflebarger, Lauren A. Walter, Toby I. Gropen, Tracy E. Madsen, Mark R. Harrigan, Ronald M. Lazar, Jamie Bice, Cassidy S. Baldwin, Michael J. Lyerly Source Type: research

Association of serum uric acid with risk of stroke in US adults: A cross-sectional study from NHANES 1999 –2020
Stroke is the second-most global death cause, only after ischemic heart disease, and third-most contributor to disability1, making it a major therapeutic challenge. More than 100 million individuals worldwide experience stroke every year, of which 795,000 cases are in the United States.2 Therefore, improved preventive strategies are needed; particularly, strategies targeting the modifiable risk factors of stroke, such as hypertension, hyperglycemia, and dyslipidemia, may help prevent more than approximately 90% of stroke cases.
Source: Journal of Stroke and Cerebrovascular Diseases - June 3, 2023 Category: Neurology Authors: Bei Gao, Yun Bao, Min Meng, Lijun Yu, Yali Lu, Rina Sa, Xiaoyan Liang, Jie Shi Source Type: research

Body mass index and waist circumference as predictors of recurrent vascular events after a recent ischemic stroke
Obesity is an independent contributor to ischemic stroke incidence. A meta-analysis of 13 studies revealed that a 5 kg/m2 increase in body mass index (BMI) was associated with a 22% increased risk of ischemic stroke in European/North American/Australian cohorts and a 35% increased risk of ischemic stroke among the Asian populations.1 In a meta-analysis of 7 prospective studies, persons in the highest waist circumference (WC) category had a relative risk of 1.41 (95% CI, 1.21 ⁠–1.56) for ischemic stroke compared with persons in the lowest category.
Source: Journal of Stroke and Cerebrovascular Diseases - July 11, 2023 Category: Neurology Authors: Kyusik Kang, Jong-Moo Park, Wi-Sun Ryu, Sang-Wuk Jeong, Dong-Eog Kim, Hong-Kyun Park, Yong-Jin Cho, Keun-Sik Hong, Kyung Bok Lee, Tai Hwan Park, Sang-Soon Park, Juneyoung Lee, Beom Joon Kim, Moon-Ku Han, Hee-Joon Bae Source Type: research

How Patient Demographics, Imaging, and Beliefs Influence Tissue-Type Plasminogen Activator Use: A Survey of North American Neurologists Clinical Sciences
Conclusions— Diagnostic certainty and likelihood of treatment with tissue-type plasminogen activator increase with additional clinical data, with the history being the most important factor for diagnostic and treatment decisions. Respondents had difficulty in interpreting the results of CT perfusion scans although they had little impact on treatment decisions. We did not identify treatment bias based on patient age, race, or sex.
Source: Stroke - July 24, 2016 Category: Neurology Authors: Shamy, M. C. F., Pugliese, M., Meisel, K., Rodriguez, R., Kim, A. S., Stahnisch, F. W., Smith, E. E. Tags: Computerized Tomography (CT), Ethics and Policy, Quality and Outcomes, Ischemic Stroke Clinical Sciences Source Type: research

Health Behaviors among Stroke Survivors in the United States: A Propensity Score-Matched Study
The American Heart Association/American Stroke Association has specific recommendations for secondary stroke prevention. The aim of this study was to compare health behaviors engagement between stroke survivors and propensity score-matched controls.
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2018 Category: Neurology Authors: Haytham Wali, Sawsan Kurdi, Jawad Bilal, Irbaz Bin Riaz, Sandipan Bhattacharjee Source Type: research

Patient Characteristics and Outcomes Associated with Decline in Stroke Volumes during the Early COVID-19 Pandemic
Recent studies have documented a decrease in evaluations of stroke patients during the early weeks of the coronavirus disease 2019 (COVID-19) outbreak in the United States (US).1 –4 This phenomenon raises concern that delays in emergent treatment and implementation of secondary stroke prevention measures may contribute to the morbidity and mortality of the pandemic. As a second wave of COVID-19 sweeps through the country, there is an urgent need for public health communica tion that targets populations most likely to delay evaluation for stroke-like symptoms.
Source: Journal of Stroke and Cerebrovascular Diseases - December 25, 2020 Category: Neurology Authors: Adam N. Wallace, Kaiz S. Asif, Daniel H. Sahlein, Steven J. Warach, Timothy Malisch, E. Francis LaFranchise, Scott Geraghty, K. Derek Kreitel, Marian P. Lamonte, Jefferson T. Miley, Daniel P. Gibson, Krishna Amuluru Source Type: research

Association Between Dispatch Complaint and Critical Prehospital Time Intervals in Suspected Stroke 911 Activations in the National Emergency Medical Services Information System, 2012 –2016
Stroke, one of the leading causes of death and disability in the United States (US), is a time sensitive emergency.1 Receiving timely treatment is associated with increased survival and better outcomes.2 –5 For every minute that treatment is delayed, a patient with stroke may lose an estimated 1.9 million neurons, leading to irreversible brain tissue damage long term disability, or death.6 Several studies have demonstrated that treatment with intravenous recombinant tissue-type plasminogen activat or (IV alteplase) can positively affect clinical outcomes when administered within a critical timeframe after ischemic stroke symptom onset.
Source: Journal of Stroke and Cerebrovascular Diseases - December 24, 2021 Category: Neurology Authors: Amena Y. Abbas, Erika C. Odom, Isaac Nwaise Source Type: research

Global Metabolomic Profiling Reveals Disrupted Lipid and Amino Acid Metabolism Between the Acute and Chronic Stages of Ischemic Stroke
Stroke is a major cause of serious disability in the United States. Previous studies found multiple associations of serum metabolites with acute ischemic stroke (AIS) compared to controls, but few of them evaluated metabolome in a longitudinal fashion. Therefore, we compared the metabolome of the acute and chronic stages of ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - January 29, 2022 Category: Neurology Authors: Evgeny V. Sidorov, Chao Xu, Jonathan Garcia-Ramiu, Apple Blair, Jorge Ortiz-Garcia, David Gordon, Juliane Chainakul, Dharambir K. Sanghera Source Type: research

Functional Recovery in Patients with Acute Stroke and Pre-Existing Disability: A Natural History Study
One million strokes occur in the United States every year, with as many as 1 in 3 occurring among patients with a pre-existing disability.1,2 Though they are a significant portion of the stroke population, such patients are often excluded from interventional trials.3-5 As a result, acute ischemic stroke patients with pre-morbid disability are often omitted from clinical practice treatment guidelines, such as for mechanical thrombectomy (MT). In the latest American Heart Association (AHA) guidelines, MT is only indicated for patients with no pre-stroke disability, as defined by a modified Rankin scale (mRS) score of 0-1.
Source: Journal of Stroke and Cerebrovascular Diseases - May 20, 2022 Category: Neurology Authors: Nicholas Vigilante, Scott Kamen, Ryan Shannon, Lauren Thau, Miriam Butler, Solomon Oak, Linda Zhang, Taryn Hester, Jesse M. Thon, James E. Siegler Source Type: research

Ischemic Stroke and Impact of Thyroid Profile at Presentation: A Systematic Review and Meta-analysis of Observational Studies
Stroke is the fifth leading cause of mortality in the United States and a leading cause of disability. A complex relationship between thyroid hormone levels and severity of, and outcome after, stroke has been described.
Source: Journal of Stroke and Cerebrovascular Diseases - August 15, 2017 Category: Neurology Authors: Rashmi Dhital, Dilli Ram Poudel, Niranjan Tachamo, Bishal Gyawali, Sijan Basnet, Pragya Shrestha, Paras Karmacharya Source Type: research

Racial Difference in Cerebral Microbleed Burden among Ischemic Stroke Patients
This study compared the number, associated factors, and topography of CMBs between African American and Caucasian ischemic stroke patients in the Mid-South United States.
Source: Journal of Stroke and Cerebrovascular Diseases - August 22, 2017 Category: Neurology Authors: Shima Shahjouei, Georgios Tsivgoulis, Mantinderpreet Singh, Michael McCormack, Nariman Noorbakhsh-Sabet, Nitin Goyal, Anne W. Alexandrov, Andrei V. Alexandrov, Ramin Zand Source Type: research

Increasing prevalence of vascular risk factors in patients with stroke: A call to action
Conclusions: Despite numerous guidelines and prevention initiatives, prevalence of hypertension, diabetes, dyslipidemia, smoking, and drug abuse in AIS increased across the 2004–2014 period. Proportion of patients with carotid stenosis, CRF, and multiple risk factors also increased. Enhanced risk factor modification strategies and implementation of evidence-based recommendations are needed for optimal stroke prevention.
Source: Neurology - November 6, 2017 Category: Neurology Authors: Otite, F. O., Liaw, N., Khandelwal, P., Malik, A. M., Romano, J. G., Rundek, T., Sacco, R. L., Chaturvedi, S. Tags: Stroke prevention, Embolism, Prevalence studies, Risk factors in epidemiology, Infarction ARTICLE Source Type: research

Disease Burden Following Non-Cardioembolic Minor Ischemic Stroke or High-Risk TIA: A GWTG-Stroke Study
We examined outcomes and Medicare payments following any severity IS or TIA as well as the subgroup with minor IS or high-risk TIA.
Source: Journal of Stroke and Cerebrovascular Diseases - October 23, 2020 Category: Neurology Authors: Brystana G. Kaufman, Shreyansh Shah, Anne S. Hellkamp, Barbara L. Lytle, Gregg C. Fonarow, Lee H. Schwamm, Eva Les én, Jonatan Hedberg, Amarjeet Tank, Edmond Fita, Narinder Bhalla, Nipun Atreja, Janet Prvu Bettger Source Type: research