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Design and Rationale of the Home Blood Pressure Telemonitoring Linked with Community Health Workers to Improve Blood Pressure (LINKED-BP) Program
This study is part of the American Heart Association RESTORE (AddREssing Social Determinants TO pRevent hypErtension) Network. This study aims to examine the effect of the LINKED-BP Program on BP reduction and to evaluate the reach, adoption, sustainability, and cost-effectiveness of the intervention.METHODS: Using a hybrid type I effectiveness-implementation design, 600 adults who have elevated BP or untreated stage 1 hypertension without diabetes, chronic kidney disease, history of cardiovascular disease (stroke or coronary heart disease) and age < 65 years will be recruited from 20 primary care practices including co...
Source: American Journal of Hypertension - April 16, 2023 Category: Cardiology Authors: Yvonne Commodore-Mensah Xiaoyue Liu Oluwabunmi Ogungbe Chidinma Ibe Johnitta Amihere Margaret Mensa Seth S Martin Deidra Crews Kathryn A Carson Lisa A Cooper Cheryl R Himmelfarb Source Type: research

Cardiac transplant and exercise cardiac rehabilitation
AbstractCardiac transplantation is the final therapeutic option for patients with end-stage heart failure. Most patients experience a favorable functional ability post-transplant. However, episodes of acute rejection, and multiple comorbidities such as hypertension, diabetes mellitus, chronic kidney disease and cardiac allograft vasculopathy are common. The number of transplants has increased steadily over the past two decades with 3,817 operations performed in the United States in 2021. Patients have abnormal exercise physiologic responses related to surgical cardiac denervation, diastolic dysfunction, and the legacy of r...
Source: Heart Failure Reviews - April 4, 2023 Category: Cardiology Source Type: research

ERLEADA ® (apalutamide), First-and-Only Next-Generation Androgen Receptor Inhibitor with Once-Daily, Single-Tablet Option, Now Available in the U.S.
HORSHAM, Pa., April 3, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced the availability of an additional tablet strength of ERLEADA® (apalutamide) in the United States. The introduction of the 240mg tablet provides the first-and-only option for a once-daily, single-tablet Androgen Receptor Inhibitor (ARI) approved for the treatment of patients with non-metastatic castration-resistant prostate cancer (nmCRPC) and for the treatment of patients with metastatic castration-sensitive prostate cancer (mCSPC).With two strengths available, healthcare professionals will have the flexibility to...
Source: Johnson and Johnson - April 3, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news

Stroke-related risk factors during pregnancy in women who underwent metabolic and bariatric surgery compared with women who have not undergone metabolic and bariatric surgery
Stroke during pregnancy is rare, occurring in 30 of 100,000 pregnancies and accounting for 7% of maternal deaths in the United States from 2016 to 2018. Metabolic and bariatric surgery (MBS) has been shown to reduce symptoms of chronic conditions that are risk factors for stroke, including hypertension, hypercholesterolemia, and diabetes in women. However, little is known about the impact of MBS on stroke risk during pregnancy.
Source: Surgery for Obesity and Related Diseases - March 31, 2023 Category: Surgery Authors: Kara M. Christopher, Xiaoyi Gao, Ahmed Abdelsalam, Brian Miremadi, Jordan Scott, Chike Ilorah, Pamela Xaverius, Guillermo Linares Tags: Original article Source Type: research

Stroke-related risk factors during pregnancy in women who had metabolic and bariatric surgery compared to women without metabolic and bariatric surgery.
Stroke during pregnancy is rare, occurring in 30 of 100,000 pregnancies, and accounting for 7% of maternal deaths in the United States from 2016 to 2018. Metabolic and bariatric surgery (MBS) have been shown to reduce symptoms of chronic conditions that are risk factors for stroke, including hypertension, hypercholesterolemia, and diabetes in women. However, little is known about the impact of MBS on stroke risk during pregnancy.
Source: Surgery for Obesity and Related Diseases - March 31, 2023 Category: Surgery Authors: Kara Christopher, Xiaoyi Gao, Ahmed Abdelsalam, Brian Miremadi, Jordan Scott, Chike Ilorah, Pamela Xaverius, Guillermo Linares Tags: Original articles Source Type: research

Young Americans Face Rising Rates of Obesity, High Blood Pressure, Diabetes
MONDAY, March 6, 2023 -- Young adults in the United States carry an increasing burden of heart health risk factors, making it more likely they’ll suffer a heart attack and stroke as they age, a new study warns. More adults ages 20 to 44 are...
Source: Drugs.com - Daily MedNews - March 6, 2023 Category: General Medicine Source Type: news

Janssen Data at ASCO GU Support Ambition to Transform Treatment of Prostate and Bladder Cancer Through Precision Medicine and Early Intervention
RARITAN, N.J., February 13, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced plans to present more than 20 abstracts featuring seven oncology therapies from its robust portfolio and pipeline at the annual American Society of Clinical Oncology (ASCO) Genitourinary (GU) Cancers Symposium, taking place in San Francisco on February 16-18. Building on more than a decade of leadership in the development of medicines for people diagnosed with GU cancers, Janssen will present data demonstrating its ambition to advance patient-centered treatment through precision medicine, real-world evidence a...
Source: Johnson and Johnson - February 13, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news

Self-reported physical functioning, cardiometabolic health conditions, and health care utilization patterns in Million Veteran Program enrollees with Traumatic Brain Injury Screening and Evaluation Program data
ConclusionsThe findings suggest that veterans who screen positive for TBI, regardless of whether they are ultimately diagnosed with TBI, are at greater risk for negative health outcomes, signifying that these veterans represent a vulnerable group that may benefit from increased clinical care and prevention efforts.
Source: Military Medical Research - January 3, 2023 Category: International Medicine & Public Health Source Type: research

Does bariatric surgery change the risk of acute ischemic stroke in patients with a history of transient ischemic attack? A nationwide analysis
CONCLUSIONS: After analyzing nationwide information, we conclude bariatric surgery helps decrease risk of AIS in patients with a history of TIA. However, this comparison is limited by the nature of the database; further studies are needed to better understand these results.PMID:36581552 | DOI:10.1016/j.soard.2022.11.013
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - December 29, 2022 Category: Surgery Authors: Roberto J Valera Cristina Botero-Fonnegra Vicente J Cogollo Mauricio Sarmiento-Cobos Lisandro Montorfano Carlos Rivera Liang Hong Emanuele Lo Menzo Samuel Szomstein Raul J Rosenthal Source Type: research

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