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Total 170 results found since Jan 2013.

Telmisartan use and risk of dementia in type 2 diabetes patients with hypertension: A population-based cohort study
by Chi-Hung Liu, Pi-Shan Sung, Yan-Rong Li, Wen-Kuan Huang, Tay-Wey Lee, Chin-Chang Huang, Tsong-Hai Lee, Tien-Hsing Chen, Yi-Chia Wei BackgroundAngiotensin receptor blockers (ARBs) may have protective effects against dementia occurrence in patients with hypertension (HTN). However, whether telmisartan, an ARB with peroxisome proliferator-activated receptor γ (PPAR-γ)–modulating effects, has additional benefits compared to other ARBs remains unclear. Methods and findingsBetween 1997 and 2013, 2,166,944 type 2 diabetes mellitus (T2DM) patients were identified from the National Health Insurance Research Database of Taiwa...
Source: PLoS Medicine - July 19, 2021 Category: Internal Medicine Authors: Chi-Hung Liu Source Type: research

Effects of long-term anti-seizure medication monotherapy on all-cause death in patients with post-stroke epilepsy: a nationwide population-based study in Taiwan
We aim to compare the effect of long-term anti-seizure medication (ASM) monotherapy on the risk of death and new ischemic stroke in patients with post-stroke epilepsy (PSE).
Source: BMC Neurology - June 21, 2021 Category: Neurology Authors: Chia-Yu Hsu, Chun-Yu Cheng, Jiann-Der Lee, Meng Lee and Bruce Ovbiagele Tags: Research Source Type: research

Could prokinetic agents protect long-term nasogastric tube-dependent patients from being hospitalized for pneumonia? A nationwide population-based case-crossover study
ConclusionProkinetic agent use had no negative association with pneumonia admission among long-term nasogastric tube-dependent patients in Taiwan.
Source: PLoS One - April 5, 2021 Category: Biomedical Science Authors: Kun-Siang Huang Source Type: research

Cross-Validation of the Factorial Validity of the Stroke Impact Scale 3.0 in Patients With Stroke
CONCLUSIONS AND RELEVANCE: Neither the eight- nor the four-domain structure of the Stroke Impact Scale 3.0 was supported, suggesting that scores may not provide valid assessments of HRQOL in clients with stroke. Further modification and validation of the Stroke Impact Scale 3.0 are warranted.WHAT THIS ARTICLE ADDS: Our findings suggest that the eight- and four-domain scores of the Stroke Impact Scale 3.0 may not be valid. Therefore, until more supporting evidence is developed, these scores should be interpreted cautiously in regard to clients' HRQOL; alternatively, other measures could be used.PMID:33657349 | DOI:10.5014/ajot.2021.040659
Source: The American Journal of Occupational Therapy - March 3, 2021 Category: Occupational Health Authors: Shih-Chieh Lee Gong-Hong Lin Yi-Jing Huang Sheau-Ling Huang Chia-Yeh Chou Hsin-Yu Chiang Ching-Lin Hsieh Source Type: research