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The Integration of Doppler Ultrasound With Two-Dimensional Echocardiography and the Noninvasive Cardiac Hemodynamic Revolution of the 1980s
In the 1970s, as cardiac imaging matured from M-mode to two-dimensional echocardiography, investigators in Norway showed that continuous-wave Doppler ultrasonography could be used to accurately measure the mean gradient and pressure half-time for stenotic mitral valves. In the 1980s, continuous-wave Doppler was validated for measurement of the pressure gradient across stenotic aortic valves, and pulsed-wave Doppler combined with two-dimensional echocardiographic imaging was validated for noninvasive measurement of stroke volume and cardiac output.
Source: Journal of the American Society of Echocardiography - October 16, 2018 Category: Cardiology Authors: Fletcher A. Miller Source Type: research

Clinical Importance of Temporal Bone Features for the Efficacy of Contrast-Enhanced Sonothrombolysis: a Retrospective Analysis of the NOR-SASS Trial
AbstractContrast-enhanced sonothrombolysis (CEST) seems to be a safe and promising treatment in acute ischemic stroke. It remains unknown if temporal bone features may influence the efficacy of CEST. We investigated the association between different temporal bone features on admission computed tomography (CT) scan and the outcome in acute ischemic stroke patients included in the randomized Norwegian Sonothrombolysis in Acute Stroke Study (NOR-SASS). Patients diagnosed as stroke mimics and those with infratentorial stroke or with incorrect insonation were excluded. We retrospectively assessed temporal bone heterogeneity (pr...
Source: Translational Stroke Research - November 8, 2017 Category: Neurology Source Type: research

Contrast ‐enhanced sonothrombolysis in acute ischemic stroke patients without intracranial large‐vessel occlusion
ConclusionCEST is safe in ischemic stroke patients without intracranial LVO. There were no differences in clinical outcomes between the treatment groups.
Source: Acta Neurologica Scandinavica - October 25, 2017 Category: Neurology Authors: C. E. Kvistad, A. Nacu, V. Novotny, N. Logallo, U. Waje ‐Andreassen, H. Naess, L. Thomassen Tags: ORIGINAL ARTICLE Source Type: research