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A Clinical and Physiological Prospective Observational Study on the Management of Pediatric Shock in the Post-Fluid Expansion as Supportive Therapy Trial Era*
CONCLUSIONS: Maintenance-only fluid therapy normalized clinical and myocardial perturbations in shock without compromising cardiac or hemodynamic function whereas fluid-bolus management of WHO shock resulted in high fatality. Troponin and lactate biomarkers of cardiac dysfunction could be promising outcome predictors in pediatric septic shock in resource-limited settings.
Source: Pediatric Critical Care Medicine - July 1, 2022 Category: Pediatrics Tags: Feature Articles Source Type: research

Results of PRospect trial to Elucidate the utility of EchocarDiography-based Cardiac ouTput in acute heart failure (PREDICT)
CONCLUSIONS: We demonstrated the predictive value of echocardiographic LV output indices for early WHF in ADHF patients with LV systolic dysfunction. These data support the motivation for routine use of echocardiography for initial assessment of ADHF.PMID:35307223 | DOI:10.1016/j.jjcc.2022.03.003
Source: Journal of Cardiology - March 21, 2022 Category: Cardiology Authors: Hiroyuki Iwano Hiroto Utsunomiya Kentaro Shibayama Hidekazu Tanaka Akihiro Isotani Toshinari Onishi Masaru Obokata Masaki Izumo Kenya Kusunose Atsuko Furukawa Masahiro Yamada Takeshi Kitai Tetsuari Onishi Masayoshi Yamamoto Shunsuke Sasaki Kotaro Nochioka Source Type: research