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Middle East Treatment Strategies and Clinical Outcomes in Patients with Atrial Fibrillation: One-Year Follow-up Data from Garfield-AF Study
ConclusionWe have found that rates of stroke and bleeding were lower, although mortality was higher, in the Middle East population. This paper describes the baseline characteristics, patterns of antithrombotic treatment and 1-year outcomes in Middle East AF patients.Trial Registrationhttp://www.clinicaltrials.gov. Identifier, NCT01090362.
Source: Advances in Therapy - March 27, 2021 Category: Drugs & Pharmacology Source Type: research

Colchicine: An ancient drug with multiple benefits.
Abstract The history of colchicine dates to ancient Egyptians when it was used for alleviation of swelling and pain. Although its popularity varied throughout the years, colchicine has been a mainstay for the treatment of several diseases, mainly rheumatic and cardiac ones. The mechanism of action of the drug involves several intracellular and extracellular targets, although interaction with tubulin is the most described. Based on several clinical trials and meta-analyses, colchicine is safely recommended as a monotherapy or as an add-on for the treatment and prevention of recurrent pericarditis, postpericardiotom...
Source: Current Pharmaceutical Design - October 23, 2020 Category: Drugs & Pharmacology Authors: El Hasbani G, Jawad A, Uthman I Tags: Curr Pharm Des Source Type: research