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Inflammation May Be the Culprit Behind Our Deadliest Diseases
In the early days of my medical residency, I met a man whom we’ll call Jason. He arrived to our emergency room on a holiday, nonchalant yet amiable, and complained of mild chest pain. Jason was tall and trim, with a strong South Boston accent and fingertips still faintly stained from his last home-improvement project. He was only 45 years old, but he looked much younger. He didn’t smoke, barely drank alcohol, and his cholesterol levels had always been normal. No one in his family had a history of heart disease. He asked us if we could work quickly—he wanted to be home for dinner with his daughters. [time-...
Source: TIME: Health - April 11, 2023 Category: Consumer Health News Authors: Shilpa Ravella Tags: Uncategorized freelance health Source Type: news

Finding the everyday miracles in life
Last week I was writing about what it takes for a miracle to happen and one of my commentators, the lovely Patsy Collins who joined me on the podcast not that long ago, pointed out that there are all sorts of miracles that happen, including some everyday miracles we never know about, because they happen behind the scenes. And it got me thinking about the all the little miracles that have happened in my life over the years. And, once I got thinking, I got into musing about what life would be like if they hadn’t happened. And, as it’s been a week of ups and downs on the exam front I thought I might as well start ...
Source: The Hysterectomy Association - August 22, 2020 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Happiness miracle Source Type: news

A Novel Homozygous Non-sense Mutation in the Catalytic Domain of MTHFR Causes Severe 5,10-Methylenetetrahydrofolate Reductase Deficiency
Conclusion: We identified a novel non-sense mutation in MTHFR gene in a single Egyptian family with severe MTHFR deficiency. The present investigation is clinically important, as it adds to the growing list of MTHFR mutations, which might help in genetic counseling of families of affected children and proper genotype-phenotype correlation. Background Severe 5,10-Methylenetetrahydrofolate reductase (MTHFR; OMIM 236250) deficiency is a rare inborn error of metabolism and inherited in an autosomal recessive fashion. It is a very common disorder of folate metabolism and is clinically characterized with low plasma methion...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Prevalence of Ischemic and Hemorrhagic Strokes in Qena Governorate, Egypt: Community-based Study
Conclusions: The overall prevalence rate of stroke is nearly the same as in other Egyptian governorates and is higher than other Arabic countries.
Source: Journal of Stroke and Cerebrovascular Diseases - June 23, 2014 Category: Neurology Authors: Eman M. Khedr, Gharib Fawi, Mohamed Abdela, Talal A. Mohammed, Mohamed A. Ahmed, Noha Abo El-Fetoh, Ahmed F. Zaki Tags: Original Articles Source Type: research