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Source: Atherosclerosis
Condition: Atrial Fibrillation

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Total 150 results found since Jan 2013.

Diabetes and Stroke: What Are the Connections?
J Stroke. 2023 Jan 3. doi: 10.5853/jos.2022.02306. Online ahead of print.ABSTRACTStroke is a major cause of death and long-term disability worldwide. Diabetes is associated with an increased risk of cardiovascular complications, including stroke. People with diabetes have a 1.5-2 times higher risk of stroke compared with people without diabetes, with risk increasing with diabetes duration. These risks may also differ according to sex, with a greater risk observed among women versus men. Several mechanisms associated with diabetes lead to stroke, including large artery atherosclerosis, cerebral small vessel disease, and car...
Source: Atherosclerosis - January 2, 2023 Category: Cardiology Authors: Ofri Mosenzon Alice Yy Cheng Alejandro A Rabinstein Simona Sacco Source Type: research

Left Atrial Mechanical Dysfunction and the Risk for Ischemic Stroke in People Without Prevalent Atrial Fibrillation or Stroke : A Prospective Cohort Study
Ann Intern Med. 2022 Dec 20. doi: 10.7326/M22-1638. Online ahead of print.NO ABSTRACTPMID:36534978 | DOI:10.7326/M22-1638
Source: Atherosclerosis - December 19, 2022 Category: Cardiology Authors: Ankit Maheshwari Faye L Norby Riccardo M Inciardi Wendy Wang Michael J Zhang Elsayed Z Soliman Alvaro Alonso Michelle C Johansen Rebecca F Gottesman Scott D Solomon Amil M Shah Lin Yee Chen Source Type: research

Serum circulating sirtuin 6 as a novel predictor of mortality after acute ischemic stroke
In this study, we aimed at evaluating the prognostic value of serum SIRT6 levels in patients with acute ischemic stroke (AIS). Serum levels of SIRT6, collected within 72 h from symptom-onset, were measured in 317 consecutively enrolled AIS patients from the COSMOS cohort. The primary endpoint of this analysis was 90-day mortality. The independent prognostic value of SIRT6 was assessed with multivariate logistic and Cox proportional regression models. 35 patients (11%) deceased within 90-day follow-up. After adjustment for established risk factors (age, NIHSS, heart failure, atrial fibrillation, and C reactive protein), SIR...
Source: Atherosclerosis - November 28, 2022 Category: Cardiology Authors: Luca Liberale Stefano Ministrini Markus Arnold Yustina M Puspitasari Thomas Pokorny Georgia Beer Natalie Scherrer Juliane Schweizer Mirjam Christ-Crain Fabrizio Montecucco Giovanni G Camici Mira Katan Kahles Source Type: research

Novel predictors and a predictive model of cerebrovascular atherosclerotic ischemic stroke based on clinical databases
CONCLUSION: The efficacy of the predictive model was acceptable as an aid in predicting cerebrovascular atherosclerotic ischemic stroke.PMID:36413433 | DOI:10.1080/01616412.2022.2149185
Source: Atherosclerosis - November 22, 2022 Category: Cardiology Authors: He Li Pei Liu Hong-Yu Ma Wei-Long Hua Yong-Xin Zhang Lei Zhang Yong-Wei Zhang Bo Hong Peng-Fei Yang Jian-Min Liu Source Type: research

Early diagnosis of intracranial atherosclerotic large vascular occlusion: A prediction model based on DIRECT-MT data
CONCLUSION: Our current prediction model based on clinical data of patients from the DIRECT-MT trial might be a promising tool for predicting ICAS-LVO.PMID:36408511 | PMC:PMC9670732 | DOI:10.3389/fneur.2022.1026815
Source: Atherosclerosis - November 21, 2022 Category: Cardiology Authors: He Li Hong-Yu Ma Lei Zhang Pei Liu Yong-Xin Zhang Xiao-Xi Zhang Zi-Fu Li Peng-Fei Xing Yong-Wei Zhang Qiang Li Peng-Fei Yang Jian-Min Liu Source Type: research

Aetiology of extracranial carotid free-floating thrombus in a prospective multicentre cohort
CONCLUSIONS: The majority of symptomatic carotid artery FFT are likely caused by local plaque rupture, more than half of which are associated with moderate to severe carotid stenosis requiring revascularisation. However, a significant number of FFTs are caused by non-atherosclerotic mechanisms warranting additional investigations.PMID:36368714 | DOI:10.1136/svn-2022-001639
Source: Atherosclerosis - November 11, 2022 Category: Cardiology Authors: Dar Dowlatshahi Cheemun Lum Bijoy K Menon Aditya Bharatha Prasham Dave Paulo Puac-Polanco Dylan Blacquiere Grant Stotts Michel Shamy Franco Momoli Rebecca Thornhill Ronda Lun Carlos Torres Source Type: research

Telomere length and the risk of cardiovascular diseases: A Mendelian randomization study
CONCLUSION: Our MR study suggested that longer telomeres were associated with decreased risk of several CVDs, including coronary atherosclerosis, myocardial infarction, ischemic heart disease, and stroke, as well as an increased risk of hypertension. Future studies are still warranted to validate the results and investigate the mechanisms underlying these associations.PMID:36352846 | PMC:PMC9637552 | DOI:10.3389/fcvm.2022.1012615
Source: Atherosclerosis - November 10, 2022 Category: Cardiology Authors: Yingjian Deng Qiang Li Faguang Zhou Guiyang Li Jianghai Liu Jialan Lv Linlin Li Dong Chang Source Type: research

The relationship between lipoprotein(a) and risk of cardiovascular disease: a Mendelian randomization analysis
CONCLUSION: This MR study suggested a causal relationship between Lp(a) and CHD, AA, and ISL, but not associated with AF, HF, IS, LIS, ISS, HBP, or PE. Our work further verifies the association between Lp(a) and various CVD, resulting in improved Lp(a) management and a reduction in the prevalence of CVD.PMID:36303257 | DOI:10.1186/s40001-022-00825-6
Source: Atherosclerosis - October 28, 2022 Category: Cardiology Authors: Shiyue Wang Li Zha Jian Chen Dongjie Du Danyang Liu Ming Zhong Rongfang Shang Dongxue Sun Chang Sun Enze Jin Source Type: research

Combined use of the GRACE ACS risk score and comorbidity indices to increase the effectiveness of hospital mortality risk assessment in patients with acute coronary syndrome
CONCLUSION: CCI and its own comorbidity model, but not CDS and CIRS, are associated with the risk of hospital mortality. The model for assessing comorbidity on a 9-point scale, but not CCI, CDS and CIRS, can significantly improve the predictive value of the GRACE scale.PMID:36286937 | DOI:10.26442/00403660.2022.07.201742
Source: Atherosclerosis - October 26, 2022 Category: Cardiology Authors: M V Zykov N V Dyachenko R M Velieva V V Kashtalap O L Barbarash Source Type: research

The relationship between vertebrobasilar artery calcification and intracranial atherosclerosis-related occlusion in thrombectomy
CONCLUSIONS: We demonstrated that VBAC is an independent risk factor for ICAS-O in patients who underwent thrombectomy. Patients free of atrial fibrillation with VBAC have more trend to be ICAS-O.PMID:36267885 | PMC:PMC9577291 | DOI:10.3389/fneur.2022.965362
Source: Atherosclerosis - October 21, 2022 Category: Cardiology Authors: Nannan Han Gejuan Zhang Shiyao Yang Haojun Ma Hanming Ge Xiao Zhang Shilin Li Yanfei Wang Xiaonan Fan Yanling Yin Yanjun Gao Wenzhen Shi Xiaobo Zhang Mingze Chang Ye Tian Source Type: research

Left Atrial Function and Arrhythmias in Relation to Small Vessel Disease on Brain MRI: The Multi-Ethnic Study of Atherosclerosis
Conclusions In individuals without a history of stroke or transient ischemic attack, alterations of LA structure and function, including enlargement, reduced strain, frequent premature atrial contractions, and intermittent AF, were associated with increased markers of small vessel disease. Detailed assessment of LA structure and function and extended ECG monitoring may enable early identification of individuals at greater risk of small vessel disease.PMID:36250665 | DOI:10.1161/JAHA.122.026460
Source: Atherosclerosis - October 17, 2022 Category: Cardiology Authors: Thomas R Austin Paul N Jensen Ilya M Nasrallah Mohamad Habes Tanweer Rashid Jeffrey B Ware Lin Yee Chen Philip Greenland Timothy M Hughes Wendy S Post Steven J Shea Karol E Watson Colleen M Sitlani James S Floyd Richard A Kronmal W T Longstreth Alain G Be Source Type: research

RNA modifications in aging-associated cardiovascular diseases
Aging (Albany NY). 2022 Sep 29;14(undefined). doi: 10.18632/aging.204311. Online ahead of print.ABSTRACTCardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide that bears an enormous healthcare burden and aging is a major contributing factor to CVDs. Functional gene expression network during aging is regulated by mRNAs transcriptionally and by non-coding RNAs epi-transcriptionally. RNA modifications alter the stability and function of both mRNAs and non-coding RNAs and are involved in differentiation, development, and diseases. Here we review major chemical RNA modifications on mRNAs and non-co...
Source: Atherosclerosis - September 30, 2022 Category: Cardiology Authors: Xinyu Yang Priyanka Gokulnath H Immo Lehmann Zhitao Hou Sun Yang Liangzhen You Guoxia Zhang Yanwei Xing Ji Lei Guoping Li Shuwen Guo Hongcai Shang Source Type: research