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Central nervous system varicella zoster vasculopathy in an immunocompromised patient
ConclusionThis clinical case and review of the literature highlights the challenges in the diagnosis and management of VZV CNS vasculopathy in immunocompromised patients.
Source: IDCases - December 29, 2018 Category: Infectious Diseases Source Type: research

An Unusual Presentation of Varicella Zoster Virus with Acute Cerebellitis and SIADH without a rash. (P2.315)
Conclusions:This report illustrates an unusual presentation of acute VZV cerebellitis and encephalitis, without a rash. To our understanding, this shows for the first time, severe acute onset neurological sequelae due to VZV.Disclosure: Dr. Lubomski has nothing to disclose. Dr. Markus has nothing to disclose. Dr. Brown has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Lubomski, M., Markus, R., Brown, L. Tags: HIV, HTLV-I, PML, Other Viral Infections, and CJD Source Type: research

Recurrent Strokes in Giant Cell Arteritis: Treatment Dilemma (P4.374)
Conclusions: Steroid resistant, aggressive GCA cases can lead to severe extracranial vasculopathy, dissection, recurrent strokes, and death. Thus we suggest that aggressive immunosuppression be considered early, particularly if complicated with arterial dissection and stroke. These patients may benefit from other potent immunosuppressant drugs such as disease modifying anti-rheumatic drugs, acyclovir, or monoclonal antibodies.Disclosure: Dr. Yadala has nothing to disclose. Dr. Kaur has nothing to disclose. Dr. Sahni has nothing to disclose. Dr. Lleva has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Yadala, V., Kaur, P., Sahni, R., Lleva, P. E. Tags: Cerebrovascular Case Reports Source Type: research

Anti glutamic acid decarboxylase antibody mediated encephalopathy while on etanercept in a patient with multiple autoimmune diseases
A 39 year old lady presented with an altered mental state and unsteadiness of gait. She had a history of juvenile idiopathic arthritis, autoimmune thyroiditis and alopecia, protein S deficiency with vena cava thrombosis, previous excision of ovarian mass and vasculitic rash. There was a previous history of ovarian mass and her immunomodulatory therapy for arthritis over the previous year was Etanercept. She used recreational cannabis but denied any other illicit drug usage. Her affect was variable and at times inappropriate with frequent laughter. She would spit regularly. There was anxiety and a prevailing sensation of do...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: MacDougall, N., Waddell, B., O'Riordan, J. I. Tags: Immunology (including allergy), Brain stem / cerebellum, Drugs: CNS (not psychiatric), Epilepsy and seizures, Infection (neurology), Stroke, Drugs misuse (including addiction), Connective tissue disease, Musculoskeletal syndromes Association of British Source Type: research