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Sulfur amino acids and atherosclerosis: a role for excess dietary methionine
The homocysteine theory of arteriosclerosis received credence when it was shown that after a methionine load, circulating homocysteine–cysteine concentrations were higher in cardiovascular disease patients than in healthy controls. Subsequent studies showing associations between homocysteine and coronary artery disease, stroke and cognitive impairment, relied on small increases in homocysteine concentration unlike the very high homocysteine seen in the rare genetic disorders that lead to homocystinuria and much higher homocysteine levels. Subsequent studies in cell culture, animals, and humans showed that a variety of ca...
Source: Annals of the New York Academy of Sciences - December 8, 2015 Category: Science Authors: Jacob Selhub, Aron M. Troen Tags: Original Article Source Type: research

Overview of the New Oral Anticoagulants: Opportunities and Challenges.
Abstract The non-vitamin K oral anticoagulants (NOACs) are replacing warfarin for many indications. These agents include dabigatran, which inhibits thrombin, and rivaroxaban, apixaban, and edoxaban, which inhibit factor Xa. All the 4 agents are licensed in the United States for stroke prevention in atrial fibrillation and for treatment of venous thromboembolism and rivaroxaban and apixaban are approved for thromboprophylaxis after elective hip or knee arthroplasty. The NOACs are at least as effective as warfarin, but are not only more convenient to administer because they can be given in fixed doses without routin...
Source: Arteriosclerosis, Thrombosis and Vascular Biology - March 19, 2015 Category: Cardiology Authors: Yeh CH, Hogg K, Weitz JI Tags: Arterioscler Thromb Vasc Biol Source Type: research

Why You Should Avoid Statins
At my anti-aging clinic, I continue to wage war against what I call the “medical-industrial complex.” And I do it for one reason only – I care more about my patients than I do about profits. Big Pharma clearly takes the opposite view. And now it seems these pharmaceutical behemoths won’t be happy until every man, woman and child is popping anti-cholesterol pills. Researchers at Duke University recently issued a report recommending that even children and people as young as 30 should be on statins, if they have just slightly elevated cholesterol levels.1 And why wouldn’t researchers at Duke recommen...
Source: Al Sears, MD Natural Remedies - February 3, 2015 Category: Complementary Medicine Authors: Dr. Al Sears Tags: Heart Health Source Type: news