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Proteomic analyses identify a potential mechanism by which extracellular vesicles aggravate ischemic stroke
Publication date: Available online 7 June 2019Source: Life SciencesAuthor(s): Xintong Wang, Jiaoqi Wang, Xiaohua Shi, Chengliang Pan, Hongyu Liu, Yue Dong, Rui Dong, Jing Mang, Zhongxin XuAbstractAimsExtracellular vesicles (EVs) are vital for information exchange between donor and recipient cells. When cells are stressed (e.g., by oxygen glucose deprivation, OGD), the complex information carried by the EVs is altered by the donor cells. Here, we aimed to analyze the proteomic differences between EVs derived from OGD-damaged cells and EVs derived from undamaged cells to explore the potential mechanisms by which EVs aggravat...
Source: Life Sciences - June 7, 2019 Category: Biology Source Type: research