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Post-translational Protein Modifications of Rare and Unconventional Types: Implications in Functions and Diseases.
Abstract Protein post-translational modification (PTM) occurs following their biosynthesis and is a key cellular event that defines their ultimate functional properties. It is an important control mechanism for display of biological functions of proteins often in a profound manner. It may switch on or off a protein's function. Several studies have been conducted to understand their mechanisms, physiological pathways and functional properties. PTMs have been shown to alter structural, conformational and physicochemical properties of proteins. So far a variety of protein modifications have been detected in physiolog...
Source: Current Medicinal Chemistry - January 17, 2016 Category: Chemistry Authors: Basak S, Lu C, Basak A Tags: Curr Med Chem Source Type: research