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Carotid artery disease: clinical features and management
The most common cause of ischaemic carotid territory stroke, around 50% of cases, is thromboembolism from stenoses at the origin of the extracranial internal carotid artery (ICA). Embolism is usually preceded by acute changes in plaque morphology, which predisposes towards overlying thrombus formation and embolization. The management of patients with carotid artery disease involves cardiovascular risk factor modification, antiplatelet and statin therapy in everyone. There is grade A, level I evidence that recently symptomatic patients with 50 –99% stenoses gain significant benefit from carotid endarterectomy (CEA), despi...
Source: Surgery (Medicine Publishing) - April 21, 2021 Category: Surgery Authors: Ross Naylor Tags: Vascular surgery – I Source Type: research

Carotid endarterectomy for symptomatic low-grade carotid stenosis
Conclusions: This study shows that CEA is a safe, effective, and durable treatment for patients with symptomatic low-grade carotid stenosis associated with unstable plaque. Patients had excellent protection against further ischemic events and survived long enough to justify the initial surgical risk. Plaque instability seems to play a major part in the onset of ischemic events, regardless the entity of lumen narrowing.
Source: Journal of Vascular Surgery - August 19, 2013 Category: Surgery Authors: Enzo Ballotta, Annalisa Angelini, Franco Mazzalai, Giacomo Piatto, Antonio Toniato, Claudio Baracchini Tags: Clinical research studies Source Type: research