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Fr127 PENTADECAPEPTIDE BPC 157 IN STROKE RATS COUNTERACTS STRESS GASTRIC LESIONS, THROMBOSIS AND INTRACRANIAL, PORTAL AND CAVAL HYPERTENSION, AND AORTAL HYPOTENSION
Source: Gastroenterology - May 1, 2021 Category: Gastroenterology Authors: Slaven Gojkovic, Jaksa Vukojevic, Ivan Krezic, Sanja Strbe, Hrvoje Vranes, Katarina Oroz, Luka Coric, Karol Simonji, Marijan Tepes, Eva Lovric, Anita Skrtic, Sven Seiwerth, Predrag Sikiric Tags: AGA Abstracts Source Type: research

Intestinal Ischemic Manifestations of COVID-19
We read with interest the article by Norsa et  al1 on intestinal ischemia in patients with coronavirus disease 2019 (COVID-19). They further highlight the coagulopathy known to cause vascular obstructions in patients with severe COVID-19, in whom microthrombi are typically found in the lung circulation; however, also myocardial infarction and ischemic stroke were reported, particularly in the late phase of the disease. The patients reported by Norsa et al had either small or large bowel ischemia, splenic infarct, or pulmonary thromboembolism, which were fatal in 4 of the 7 cases.
Source: Gastroenterology - December 29, 2020 Category: Gastroenterology Authors: Antonio Ponzetto, John Holton, Massimo Porta Tags: Correspondence Source Type: research

Cardiovascular Risk in Inflammatory Bowel Disease: It’s a Heartache!
Rungoe C, Basit S, Ranthe MF, et al. Risk of ischemic heart disease in patients with inflammatory bowel disease: a nationwide Danish cohort study. Gut 2013;62:689–694. Besides predisposing to venous thromboembolism, chronic systemic inflammation is an independent risk factor for atherosclerosis by promoting plaque formation, inducing endothelial dysfunction, and promoting platelet activation and aggregation (N Engl J Med 2005;352:1685–1695). Epidemiologic studies have shown that chronic inflammatory diseases such as rheumatoid arthritis and systemic lupus erythematosus are associated with premature atherosclerosis an...
Source: Gastroenterology - October 28, 2013 Category: Gastroenterology Authors: Siddharth Singh, Edward V. Loftus Tags: Selected Summaries Source Type: research