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Neurosurgery in times of a pandemic: a survey of neurosurgical services during the COVID-19 outbreak in the Veneto region in Italy.
CONCLUSIONS: This multicenter study describes the effects of a COVID-19 outbreak on neurosurgical activities in a vast region in Italy. Remodulation of neurosurgical activities has resulted in a significant reduction of elective and emergency surgeries compared to previous years. Most likely this is a combined result of cancellation of elective and postponable surgeries, increase of conservative management, increase in social restrictions, and in patients' fear of accessing hospitals. Curiously, only endovascular procedures for AIS have increased, possibly due to reduced physical activity or increased thrombosis in SARS-Co...
Source: Neurosurgical Focus - December 1, 2020 Category: Neurosurgery Authors: Raneri F, Rustemi O, Zambon G, Del Moro G, Magrini S, Ceccaroni Y, Basso E, Volpin F, Cappelletti M, Lardani J, Ferraresi S, Guida F, Chioffi F, Pinna G, Canova G, d'Avella D, Sala F, Volpin L Tags: Neurosurg Focus Source Type: research

Endovascular management of basilar artery occlusion secondary to fusiform aneurysm with intraluminal thrombus.
Abstract Acute basilar artery occlusion is one of the most devastating subtypes of ischemic stroke with an extremely high morbidity and mortality rate. The most common causes include embolism, large-artery atherosclerosis, penetrating small-artery disease, and arterial dissection. The heart and vertebral arteries are the main source of emboli in embolic basilar occlusions. The authors present an uncommon acute basilar occlusion secondary to a fusiform aneurysm with intraluminal thrombus. The patient underwent a mechanical thrombectomy with successful recanalization, but persistent intraluminal thrombus. The author...
Source: Neurosurgical Focus - January 1, 2019 Category: Neurosurgery Authors: Beer-Furlan A, Dasenbrock HH, Joshi KC, Chen M Tags: Neurosurg Focus Source Type: research

Unruptured aneurysms in the elderly: perioperative outcomes and cost analysis of endovascular coiling and surgical clipping.
CONCLUSIONS Intervention with CAC and CACo in the elderly is resource intensive and is associated with higher risk than in the nonelderly. Those deciding between intervention and conservative management should consider these risks and costs, especially the 2.2% postoperative mortality rate associated with CAC in the elderly population. Further comparative cost-effectiveness research is needed to weigh these costs and outcomes against those of conservative management. PMID: 29712518 [PubMed - in process]
Source: Neurosurgical Focus - May 1, 2018 Category: Neurosurgery Authors: Silva NA, Shao B, Sylvester MJ, Eloy JA, Gandhi CD Tags: Neurosurg Focus Source Type: research

Neuroprotective strategies and the underlying molecular basis of cerebrovascular stroke.
Abstract Stroke is a leading cause of disability in the US. Although there has been significant progress in the area of medical and surgical thrombolytic technologies, neuroprotective agents to prevent secondary cerebral injury and to minimize disability remain limited. Only limited success has been reported in preclinical and clinical trials evaluating a variety of compounds. In this review, the authors discuss the most up-to-date information regarding the underlying molecular biology of stroke as well as strategies that aim to mitigate this complex signaling cascade. Results of historical research trials involvi...
Source: Neurosurgical Focus - April 1, 2017 Category: Neurosurgery Authors: Karsy M, Brock A, Guan J, Taussky P, Kalani MY, Park MS Tags: Neurosurg Focus Source Type: research

Novel balloon-and-aspiration method for cerebral venous sinus thrombosis: dental-floss technique.
Abstract Cerebral venous sinus thrombosis is sometimes fatal. The standard treatment for sinus thrombosis is anticoagulation, but endovascular intervention must be considered when medical treatment fails. Mechanical thrombectomy is usually required when a large clot burden exits. Unfortunately, in sinus thrombosis attributable to a clot burden larger than that in an intracranial artery, the conventional technique used for intraarterial acute stroke intervention with a stent retriever and/or aspiration is not very effective. The authors describe here their endovascular approach to mechanical thrombectomy for sinus ...
Source: Neurosurgical Focus - April 1, 2017 Category: Neurosurgery Authors: Matsuda Y, Okada H, Chung J, Webster Crowley R, Lopes DK Tags: Neurosurg Focus Source Type: research

Morphometrics as a predictor of perioperative morbidity after lumbar spine surgery.
CONCLUSIONS The morphometric measurement of psoas muscle size may be a sensitive predictive tool compared with other risk factors for perioperative morbidity in male patients undergoing lumbar surgery. PMID: 26424345 [PubMed - in process]
Source: Neurosurgical Focus - October 1, 2015 Category: Neurosurgery Authors: Zakaria HM, Schultz L, Mossa-Basha F, Griffith B, Chang V Tags: Neurosurg Focus Source Type: research