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Condition: Thrombosis
Procedure: Carotid Endarterectomy

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Total 111 results found since Jan 2013.

Long-term outcomes of eversion and conventional carotid endarterectomy: A multicenter clinical trial
CONCLUSION: ECEA is beneficial over CCEA in a long term.PMID:35321600 | DOI:10.1177/17085381221084803
Source: Vascular - March 24, 2022 Category: Surgery Authors: Yuri V Belov Anton N Kazantsev Roman A Vinogradov Alexander V Korotkikh Source Type: research

Plaque Evaluation by Ultrasound and Transcriptomics Reveals BCLAF1 as a Regulator of Smooth Muscle Cell Lipid Transdifferentiation in Atherosclerosis
CONCLUSIONS: Plaque echogenicity correlated with enrichment of distinct molecular pathways and identified BCLAF1, previously not described in atherosclerosis, as the most significant gene. Functionally, BCLAF1 seems necessary for survival and transdifferentiation of SMCs into a macrophage-like phenotype. The role of BCLAF1 in plaque vulnerability should be further evaluated.PMID:35321563 | DOI:10.1161/ATVBAHA.121.317018
Source: Arteriosclerosis, Thrombosis and Vascular Biology - March 24, 2022 Category: Cardiology Authors: Urszula Rykaczewska Quanyi Zhao Peter Saliba-Gustafsson Mariette Lengquist Malin Kronqvist Otto Bergman Zhiqiang Huang Kent Lund Katarina Waden Vila Z Pons Kenneth Caidahl Josefin Skogsberg Vladana Vukojevic Jan H N Lindeman Joy Roy G öran K Hansson Ecka Source Type: research

Lipid Droplet Protein PLIN1 Regulates Inflammatory Polarity in Human Macrophages and is Involved in Atherosclerotic Plaque Development by Promoting Stable Lipid Storage
CONCLUSION: There was a relationship between macrophage polarity, cytosolic LD size, and PLIN1/PLIN2 expression levels. PLIN2 was mainly expressed in arterial plaques in symptomatic stroke patients, and associated with the inflammatory phenotype of human macrophages, while PLIN1 expression is closely associated with plaque stability and the anti-inflammatory phenotype.PMID:35662076 | DOI:10.5551/jat.63153
Source: Journal of Atherosclerosis and Thrombosis - June 6, 2022 Category: Cardiology Authors: Kyu Yong Cho Hideaki Miyoshi Akinobu Nakamura Andrew S Greenberg Tatsuya Atsumi Source Type: research