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A Systematic Review and Meta-analysis of Peri-Procedural Outcomes in Patients Undergoing Carotid Interventions Following Thrombolysis
CONCLUSION: Peri-procedural ICH and local haematoma were significantly more frequent in patients undergoing CEA after TT (vs. no TT), although there were no randomised comparisons. Peri-procedural hazards were also significantly higher for CAS after TT. The inverse relationship between timing to CEA and peri-procedural stroke/death mandates careful patient selection and suggests that it may be safer to defer CEA for six-seven days after TT.PMID:34266765 | DOI:10.1016/j.ejvs.2021.06.003
Source: PubMed: Eur J Vasc Endovasc ... - July 16, 2021 Category: Surgery Authors: Stavros K Kakkos Melina Vega de Ceniga Ross Naylor Source Type: research

Carotid Endarterectomy Following Intravenous Thrombolysis in the UK
CONCLUSION: The use of ivTT before CEA in stroke patients was not associated with an increased risk of 30 day stroke, but there was an increase in the risk of neck haematoma.PMID:34088616 | DOI:10.1016/j.ejvs.2021.03.033
Source: PubMed: Eur J Vasc Endovasc ... - June 5, 2021 Category: Surgery Authors: Amundeep S Johal A Ross Naylor Arun D Pherwani Qiuju Li Panagiota Birmpili Sam Waton Richard O'Neill Jonathan R Boyle David A Cromwell Source Type: research

Long-term Outcome After EndoVAC Hybrid Repair of Infected Vascular Reconstructions.
CONCLUSION: The EndoVAC technique is an alternative, less invasive, option for treatment of infected vascular reconstructions in selected cases, when neither traditional radical surgery, nor conservative simple negative pressure wound therapy are considered feasible or safe. The exact indications for this alternative hybrid treatment need to be established. PMID: 26944600 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - March 1, 2016 Category: Surgery Authors: Thorbjørnsen K, Djavani Gidlund K, Björck M, Kragsterman B, Wanhainen A Tags: Eur J Vasc Endovasc Surg Source Type: research

Mechanism of Procedural Stroke Following Carotid Endarterectomy or Carotid Artery Stenting Within the International Carotid Stenting Study (ICSS) Randomised Trial.
CONCLUSION: Although the mechanism of procedural stroke in both CAS and CEA is diverse, haemodynamic disturbance is an important mechanism. Careful attention to blood pressure control could lower the incidence of procedural stroke. PMID: 26160210 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - July 6, 2015 Category: Surgery Authors: Huibers A, Calvet D, Kennedy F, Czuriga-Kovács KR, Featherstone RL, Moll FL, Brown MM, Richards T, de Borst GJ Tags: Eur J Vasc Endovasc Surg Source Type: research

Identification of Patients with a Histologically Unstable Carotid Plaque Using Ultrasonic Plaque Image Analysis.
CONCLUSIONS: Computerized plaque analysis has the potential to identify patients with histologically unstable carotid plaques. This model requires validation, but offers the potential to influence patient selection for emergency interventions and the monitoring of medical therapy. PMID: 24947079 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - June 16, 2014 Category: Surgery Authors: Salem MK, Bown MJ, Sayers RD, West K, Moore D, Nicolaides A, Robinson TG, Naylor AR Tags: Eur J Vasc Endovasc Surg Source Type: research

Closing the Loop: A 21-year Audit of Strategies for Preventing Stroke and Death Following Carotid Endarterectomy.
The objective of this review was to identify causes of stroke/death after carotid endarterectomy (CEA) and to develop transferable strategies for preventing stroke/death after CEA, via an overview of a 21-year series of themed research and audit projects. Three preventive strategies were identified: (i) intra-operative transcranial Doppler (TCD) ultrasound and completion angioscopy which virtually abolished intra-operative stroke, primarily through the removal of residual luminal thrombus prior to restoration of flow; (ii) dual antiplatelet therapy with a single 75-mg dose of clopidogrel the night before surgery in additio...
Source: PubMed: Eur J Vasc Endovasc ... - June 13, 2013 Category: Surgery Authors: Naylor AR, Sayers RD, McCarthy MJ, Bown MJ, Nasim A, Dennis MJ, London NJ, Bell PR Tags: Eur J Vasc Endovasc Surg Source Type: research