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In Vitro Analysis of the Efficacy of Endovascular Thrombectomy Techniques according to the Vascular Tortuosity Using 3D Printed Models INTERVENTIONAL
CONCLUSIONS: The tortuous vascular anatomy may worsen the first-pass effect and distal emboli rates. The combined techniques failed to show improvement in outcome due to the shearing-off phenomenon of the thrombus during retrieval.
Source: American Journal of Neuroradiology - October 5, 2022 Category: Radiology Authors: Kim, J. H., Kim, B. M., Kim, D. J. Tags: INTERVENTIONAL Source Type: research

Endovascular Thrombectomy of Calcified Emboli in Acute Ischemic Stroke: A Multicenter Study INTERVENTIONAL
CONCLUSIONS: Acute ischemic stroke with large-vessel occlusion due to calcified emboli is a rare entity in patients undergoing thrombectomy, with considerably worse angiographic outcome and a higher mortality compared with patients with noncalcified thrombi. Good functional recovery at 3 months can still be achieved in about a quarter of patients.
Source: American Journal of Neuroradiology - March 16, 2020 Category: Radiology Authors: Maurer, C. J., Dobrocky, T., Joachimski, F., Neuberger, U., Demerath, T., Brehm, A., Cianfoni, A., Gory, B., Berlis, A., Gralla, J., Möhlenbruch, M. A., Blackham, K. A., Psychogios, M. N., Zickler, P., Fischer, S. Tags: INTERVENTIONAL Source Type: research

Flow Patterns in Carotid Webs: A Patient-Based Computational Fluid Dynamics Study EXTRACRANIAL VASCULAR
CONCLUSIONS: Carotid webs are associated with increased recirculation zones and regional increased wall shear stress metrics that are associated with disturbed flow. These findings suggest that a carotid web might stimulate thrombus formation, which increases the risk of acute ischemic stroke.
Source: American Journal of Neuroradiology - April 10, 2019 Category: Radiology Authors: Compagne, K. C. J., Dilba, K., Postema, E. J., van Es, A. C. G. M., Emmer, B. J., Majoie, C. B. L. M., van Zwam, W. H., Dippel, D. W. J., Wentzel, J. J., van der Lugt, A., Gijsen, F. J. H., for the MR CLEAN investigators Tags: EXTRACRANIAL VASCULAR Source Type: research

Predictors and Clinical Impact of Delayed Stent Thrombosis after Thrombectomy for Acute Stroke with Tandem Lesions INTERVENTIONAL
CONCLUSIONS: We observed a non-negligible rate of delayed stent thrombosis with significant negative impact on clinical outcome. Future studies should systematically measure and report stent patency rates.
Source: American Journal of Neuroradiology - March 13, 2019 Category: Radiology Authors: Pop, R., Zinchenko, I., Quenardelle, V., Mihoc, D., Manisor, M., Richter, J. S., Severac, F., Simu, M., Chibbaro, S., Rouyer, O., Wolff, V., Beaujeux, R. Tags: INTERVENTIONAL Source Type: research

Radiomics-Based Intracranial Thrombus Features on CT and CTA Predict Recanalization with Intravenous Alteplase in Patients with Acute Ischemic Stroke FUNCTIONAL
CONCLUSIONS: Thrombus radiomics features derived from NCCT and CTA are more predictive of recanalization with IV alteplase in patients with acute ischemic stroke with proximal occlusion than previously known thrombus imaging features such as length, volume, and permeability.
Source: American Journal of Neuroradiology - January 11, 2019 Category: Radiology Authors: Qiu, W., Kuang, H., Nair, J., Assis, Z., Najm, M., McDougall, C., McDougall, B., Chung, K., Wilson, A. T., Goyal, M., Hill, M. D., Demchuk, A. M., Menon, B. K. Tags: FUNCTIONAL Source Type: research

Feasibility of Permanent Stenting with Solitaire FR as a Rescue Treatment for the Reperfusion of Acute Intracranial Artery Occlusion INTERVENTIONAL
CONCLUSIONS: Permanent stent placement with the Solitaire FR compared with other self-expanding stents appears to be feasible and safe as a rescue tool for refractory intra-arterial therapy.
Source: American Journal of Neuroradiology - February 13, 2018 Category: Radiology Authors: Woo, H. G., Sunwoo, L., Jung, C., Kim, B. J., Han, M.- K., Bae, H.- J., Bae, Y. J., Choi, B. S., Kim, J. H. Tags: INTERVENTIONAL Source Type: research

Emergent Endovascular Management of Long-Segment and Flow-Limiting Carotid Artery Dissections in Acute Ischemic Stroke Intervention with Multiple Tandem Stents EXTRACRANIAL VASCULAR
CONCLUSIONS: Emergent stent reconstruction of long-segment and flow-limiting carotid dissections in acute ischemic stroke intervention is safe and effective, with favorable clinical outcomes, allowing successful thrombectomy, vessel salvage, restoration of cerebral perfusion, and/or prevention of recurrent thromboembolic stroke.
Source: American Journal of Neuroradiology - January 10, 2017 Category: Radiology Authors: Ansari, S. A., Kühn, A. L., Honarmand, A. R., Khan, M., Hurley, M. C., Potts, M. B., Jahromi, B. S., Shaibani, A., Gounis, M. J., Wakhloo, A. K., Puri, A. S. Tags: EXTRACRANIAL VASCULAR Source Type: research

Residual Thromboembolic Material in Cerebral Arteries after Endovascular Stroke Therapy Can Be Identified by Dual-Energy CT ADULT BRAIN
CONCLUSIONS: Dual-energy CT may be valuable in the detection of clot persistence or early re-thrombosis without the necessity of additional contrast administration. However, its relevance for the prediction of outcomes remains to be determined in further studies.
Source: American Journal of Neuroradiology - August 13, 2015 Category: Radiology Authors: Grams, A. E., Knoflach, M., Rehwald, R., Willeit, J., Sojer, M., Gizewski, E. R., Glodny, B. Tags: ADULT BRAIN Source Type: research

Endovascular Recanalization in Acute Ischemic Stroke Using the Solitaire FR Revascularization Device with Adjunctive C-Arm CT Imaging INTERVENTIONAL
SUMMARY: In this clinical report, we examined a single-center experience by using the Solitaire FR Revascularization Device in the treatment of acute ischemic stroke in which there was poor initial visualization of the occluded arterial branches by using biplanar cerebral angiography. In all cases, adjunctive C-arm CT was used during the deployment of the thrombectomy device to gain additional information regarding device placement and expansion. Outcome measures included the extent of reperfusion, posttreatment changes in NIHSS scores, posttreatment TICI scores, cerebral hemorrhage, and survival. Clot removal with success...
Source: American Journal of Neuroradiology - July 15, 2015 Category: Radiology Authors: Mitchell, B. D., Chinnadurai, P., Chintalapani, G., Morsi, H. A., Shaltoni, H., Mawad, M. E. Tags: INTERVENTIONAL Source Type: research

4D-CTA in Neurovascular Disease: A Review REVIEW ARTICLES
This article provides a description of 4D-CTA techniques and a review of the available literature on the application of 4D-CTA for the evaluation of intracranial vascular malformations and hemorrhagic and ischemic stroke. Most of the research performed to date consists of observational cohort studies or descriptive case series. These studies show that intracranial vascular malformations can be adequately depicted and classified by 4D-CTA, with DSA as the reference standard. In ischemic stroke, 4D-CTA better estimates thrombus burden and the presence of collateral vessels than conventional CTA. In intracranial hemorrhage, 4...
Source: American Journal of Neuroradiology - June 11, 2015 Category: Radiology Authors: Kortman, H. G. J., Smit, E. J., Oei, M. T. H., Manniesing, R., Prokop, M., Meijer, F. J. A. Tags: REVIEW ARTICLES Source Type: research

The Curved MCA: Influence of Vessel Anatomy on Recanalization Results of Mechanical Thrombectomy after Acute Ischemic Stroke INTERVENTIONAL
CONCLUSIONS: This retrospective analysis showed that mechanical thrombectomy in the anterior circulation was significantly less often successful in patients with large vessel angles. Therefore, vessel curvature significantly influences the results of mechanical thrombectomy with stent retrievers for treatment of acute ischemic stroke. Further work is needed to understand the underlying causality.
Source: American Journal of Neuroradiology - May 15, 2015 Category: Radiology Authors: Schwaiger, B. J., Gersing, A. S., Zimmer, C., Prothmann, S. Tags: INTERVENTIONAL Source Type: research

Collateral Score Complements Clot Location in Predicting the Outcome of Intravenous Thrombolysis BRAIN
CONCLUSIONS: A proximal occlusion in the anterior circulation is associated with poorer collateral status compared with a more distal occlusion. Both the clot location and collateral score are important and independent predictors of favorable clinical outcome of hyperacute stroke treated with intravenous thrombolysis. The location of the clot is a stronger determinant of the outcome than the collateral score.
Source: American Journal of Neuroradiology - October 8, 2014 Category: Radiology Authors: Saarinen, J. T., Rusanen, H., Sillanpaa, N. Tags: BRAIN Source Type: research

Pretreatment Advanced Imaging in Patients with Stroke Treated with IV Thrombolysis: Evaluation of a Multihospital Data Base BRAIN
CONCLUSIONS: Use of advanced imaging is increasing in patients treated with IV thrombolysis. While there were differences in outcomes among imaging groups, the clinical effect of advanced imaging remains unclear.
Source: American Journal of Neuroradiology - March 13, 2014 Category: Radiology Authors: McDonald, J. S., Fan, J., Kallmes, D. F., Cloft, H. J. Tags: BRAIN Source Type: research

Thrombus Attenuation Does Not Predict Angiographic Results of Mechanical Thrombectomy with Stent Retrievers FELLOWS' JOURNAL CLUB
CONCLUSIONS: In contrast to results of other revascularization procedures as published in a recent study, the angiographic result of mechanical thrombectomy with stent retrievers is not predicted by thrombus attenuation.
Source: American Journal of Neuroradiology - November 15, 2013 Category: Radiology Authors: Yilmaz, U., Roth, C., Reith, W., Papanagiotou, P. Tags: FELLOWS ' JOURNAL CLUB Source Type: research

4D CT Angiography More Closely Defines Intracranial Thrombus Burden Than Single-Phase CT Angiography BRAIN
CONCLUSIONS: As the result of an increased sensitivity for collateral flow, 4D-CTA temporal maximum intensity projection more closely outlines intracranial thrombi than conventional single-phase CT angiography. Our findings can be helpful when planning acute neurointervention. Further research is necessary to validate our data and assess the use of 4D-CTA in predicting response to different recanalization strategies.
Source: American Journal of Neuroradiology - October 8, 2013 Category: Radiology Authors: Frolich, A. M. J., Schrader, D., Klotz, E., Schramm, R., Wasser, K., Knauth, M., Schramm, P. Tags: BRAIN Source Type: research

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