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Specialty: Neurology
Condition: Thrombosis

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Total 3681 results found since Jan 2013.

Determinants of early case‐fatality among stroke patients in Maputo, Mozambique and impact of in‐hospital complications
The burden of stroke is increasing in developing countries that struggle to manage it efficiently. We identified determinants of early case‐fatality among stroke patients in Maputo, Mozambique, to assess the impact of in‐hospital complications. Patients admitted to any hospital in Maputo with a new stroke event were prospectively registered (n = 651) according to the World Health Organization's STEPwise approach, in 2005–2006. We assessed the determinants of in‐hospital and 28‐day fatality, independently of age, gender and education, and computed population attributable fractions. In‐hospital mortality was ...
Source: International Journal of Stroke - January 1, 2013 Category: Neurology Authors: Joana Gomes, Albertino Damasceno, Carla Carrilho, Vitória Lobo, Hélder Lopes, Tavares Madede, Pius Pravinrai, Carla Silva‐Matos, Domingos Diogo, Ana Azevedo, Nuno Lunet Tags: Panorama Source Type: research

Dehydration Is Associated with More Severe Hemispatial Neglect after Stroke (S02.004)
CONCLUSIONS: Patients who are dehydrated at the time of presentation with stroke have more severe stroke symptoms, independent of stroke severity. This represents an opportunity to evaluate our hydration practices in patients with varying degrees of cardiac dysfunction during the acute stroke period in order to prescribe more precise fluid resuscitation algorithms. Future clinical trials designed to evaluate fluid resuscitation practices at the time of ischemic stroke are needed.Disclosure: Dr. Bahouth has nothing to disclose. Dr. Bahrainwala has nothing to disclose. Dr. Hillis has received personal compensation in an edit...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Bahouth, M., Bahrainwala, Z., Hillis, A., Gottesman, R. Tags: S02 Acute Stroke Therapy Source Type: research

Totaled Health Risks in Vascular Events Score Predicts Clinical Outcomes in Patients With Cardioembolic and Other Subtypes of Ischemic Stroke Clinical Sciences
Conclusions— The THRIVE score is a simple tool that helps clinicians estimate good outcome and death after ischemic stroke.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Lei, C., Wu, B., Liu, M., Chen, Y., Yang, H., Wang, D., Lin, S., Hao, Z. Tags: Acute Cerebral Infarction Clinical Sciences Source Type: research

Stroke and Major Bleeding Risk in Elderly Patients Aged >=75 Years With Atrial Fibrillation: The Loire Valley Atrial Fibrillation Project Clinical Sciences
Conclusions— Elderly patients with AF have a higher risk of stroke and bleeding, but the benefits of VKA therapy for stroke/thromboembolism or mortality were present regardless of increasing age.
Source: Stroke - December 22, 2014 Category: Neurology Authors: Lip, G. Y. H., Clementy, N., Pericart, L., Banerjee, A., Fauchier, L. Tags: Health policy and outcome research Clinical Sciences Source Type: research

Functional Recovery at 3 Months in Stroke Patients Not Receiving Thrombolytic Therapy: The Comparison Between Patients Arriving Earlier and Later Than 4.5 Hours
Conclusion: Stroke patients arriving at the hospital within and after 4.5 hours of the onset who did not receive the rtPA did not have significant differences in the functional outcomes and quality of life at 3 months. However, the eligibility for rtPA is not known before arriving at the hospital so that the necessity of seeking medical treatment as quickly as possible is still warranted. Increasing effective public awareness regarding stroke risk factors and care should be implemented.
Source: Journal of Stroke and Cerebrovascular Diseases - November 30, 2012 Category: Neurology Authors: Sujittra Duangjit, Weerasak Muangpaisan, Wattanachai Chotinaiwattarakul, Pornpatr Dharmasaroja Tags: Original Articles Source Type: research

Thrombolytic Therapy Is an Only Determinant Factor for Stroke Evolution in Large Anterior Choroidal Artery Infarcts
Conclusions: Thrombolytic therapy is an only determinant factor for stroke evolution in large AChA infarcts, which reduced the risk of stroke evolution and improved functional outcome.
Source: Journal of Stroke and Cerebrovascular Diseases - October 16, 2013 Category: Neurology Authors: Meng-Chen Wu, Li-Kai Tsai, Chung-Chu Wu, Shin-Joe Yeh, Sung-Chun Tang, Yun-Ju Chen, Chien-Lin Chen, Jiann-Shing Jeng Tags: Original Articles Source Type: research

Stroke in Patients With Aortic Stenosis: The Simvastatin and Ezetimibe in Aortic Stenosis Study Clinical Sciences
Conclusions— In patients with aortic stenosis not prescribed oral anticoagulation, atrial fibrillation, AVR with concomitant coronary artery bypass grafting, and CHA2DS2-VASc score were the major predictors of stroke. Incident stroke was strongly associated with mortality. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00092677.
Source: Stroke - June 23, 2014 Category: Neurology Authors: Greve, A. M., Dalsgaard, M., Bang, C. N., Egstrup, K., Ray, S., Boman, K., Rossebo, A. B., Gohlke-Baerwolf, C., Devereux, R. B., Kober, L., Wachtell, K. Tags: Thrombosis risk factors, CV surgery: valvular disease, Acute Cerebral Infarction Clinical Sciences Source Type: research

Heart rate variability and baroreceptor sensitivity in acute stroke: a systematic review
BackgroundAutonomic nervous system dysfunction is common after acute stroke and is associated with elevated risk of cardiac arrhythmia and mortality. Heart rate variability and baroreceptor sensitivity have been investigated as parameters of autonomic nervous system dysfunction for the prediction of stroke outcome. SummaryWe performed a systematic literature review on heart rate variability and baroreceptor sensitivity as parameters for autonomic nervous function in acute stroke. Twenty‐two studies were included. Associations between heart rate variability or baroreceptor sensitivity and stroke severity, early and late c...
Source: International Journal of Stroke - July 23, 2015 Category: Neurology Authors: Laetitia Yperzeele, Robbert‐Jan van Hooff, Guy Nagels, Ann De Smedt, Jacques De Keyser, Raf Brouns Tags: Systematic review Source Type: research

Clinical Predictors of Hemorrhagic Transformation in Non Lacunar Ischemic Stroke (P6.041)
Conclusions: predictors for HT in our cohort were also related with severe vascular disease. Identification of these high risk patients is crucial in clinical decision making regarding thrombolytic treatment and optimal timing for antithrombotic therapy initiation.Disclosure: Dr. Zurru has nothing to disclose. Dr. Colla Machado has nothing to disclose. Dr. Alonzo has nothing to disclose. Dr. Brescacin has nothing to disclose. Dr. Pigretti has nothing to disclose. Dr. Luzzi has nothing to disclose. Dr. Balian has nothing to disclose. Dr. Waisman has nothing to disclose. Dr. Cristiano has received personal compensation for a...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Zurru, M., Colla Machado, P., Alonzo, C., Brescacin, L., Pigretti, S., Luzzi, A., Balian, N., Waisman, G., Cristiano, E. Tags: In-Hospital Stroke and Stroke Complications Source Type: research

Multiple Myeloma Stage I, II and Renal Insufficiency Are Associated with Increased Stroke Risk (S31.003)
Conclusion: In multiple myeloma,patient’s renal insufficiency and MM Stage I and II were independent predictors of increased stroke risk. Besides these hypercoagulability, atrial fibrillation, watershed strokes and small vessel disease played important role.Disclosure: Dr. Limaye has nothing to disclose. Dr. Ravilla has nothing to disclose. Dr. Appalnaidu has nothing to disclose. Dr. Papanikolaou has nothing to disclose. Dr. Waheed has nothing to disclose. Dr. Hinduja has nothing to disclose.
Source: Neurology - February 7, 2016 Category: Neurology Authors: Limaye, K., Ravilla, R., Sasapu, A., Papanikolaou, X., Waheed, S., Hinduja, A. Tags: Stroke Risk, Outcomes, and Complications Source Type: research

Biomarker Application for Precision Medicine in Stroke
AbstractStroke remains one of the leading causes of long-term disability and mortality despite recent advances in acute thrombolytic therapies. In fact, the global lifetime risk of stroke in adults over the age of 25 is approximately 25%, with 24.9 million cases of ischemic stroke and 18.7 million cases of hemorrhagic stroke reported in 2015. One of the main challenges in developing effective new acute therapeutics and enhanced long-term interventions for stroke recovery is the heterogeneity of stroke, including etiology, comorbidities, and lifestyle factors that uniquely affect each individual stroke survivor. In this com...
Source: Translational Stroke Research - December 17, 2019 Category: Neurology Source Type: research

Postthrombolysis outcomes in acute ischemic stroke patients of Asian race‐ethnicity
ConclusionsOur data indicate that Asian patients derive benefit from thrombolytic therapy.
Source: International Journal of Stroke - March 12, 2013 Category: Neurology Authors: Nishant K. Mishra, Bernard P. L. Chan, Hock‐Luen Teoh, Chang‐Hui Meng, Kennedy R. Lees, Christopher Chen, Vijay K. Sharma, Tags: Research Source Type: research

Thrombolysis Despite Recent Stroke: A Case Series Brief Reports
Conclusions— In our center, we thrombolysed 6 patients despite recent stroke. Three patients had asymptomatic petechial hemorrhagic transformation within the area of subacute infarct, without apparent neurological worsening. Prospective studies are needed to explore the possible safety of tissue-type plasminogen activator in the context of previous subacute stroke in otherwise eligible patients.
Source: Stroke - May 24, 2013 Category: Neurology Authors: Alhazzaa, M., Sharma, M., Blacquiere, D., Stotts, G., Hogan, M., Dowlatshahi, D. Tags: Acute Cerebral Infarction, Thrombolysis Brief Reports Source Type: research

Body mass index and acute ischemic stroke outcomes
ConclusionsBeing overweight or obese is associated with a better functional outcome and reduced mortality in patients of acute ischemic stroke. However, the definition of an ‘optimal’ body mass index, in relation to stroke outcomes, may be affected by age, gender, and use of thrombolytic therapy.
Source: International Journal of Stroke - October 22, 2013 Category: Neurology Authors: M. Saini, M. Saqqur, A. Shuaib, Tags: Research Source Type: research

Unchanged Utilization of Endovascular Treatment in Acute Ischemic Stroke Patients in the post IMS-III era (P4.295)
Conclusion: Contrary to expectations, there has been no reduction in the utilization of endovascular treatment among acute ischemic stroke patients after IMS-III, MR RESCUE and SYNTHESIS EXPANSION results were published.Disclosure: Dr. Hassan has nothing to disclose. Dr. Bezzina has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Jones-Fullingim has nothing to disclose. Dr. Sanchez has nothing to disclose. Dr. Tekle has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Hassan, A., Bezzina, C., Malik, A., Jones-Fullingim, L., Sanchez, C., Tekle, W., Qureshi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Ischemic Stroke Treatment Source Type: research