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Source: Journal of the Neurological Sciences
Condition: Thrombosis
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Total 32 results found since Jan 2013.
Saving the brain initiative – Developing an effective hub-and-spoke model to improve the acute stroke management pathways in urban India
We aimed to develop and evaluate a hub-and-spoke model in the East Delhi by assessing knowledge and creating awareness through sensitization programs in target communities and among general physicians (GPs) along with implementation of a standard stroke management protocol (SMP) at our institute in order to extend the benefit of thrombolytic therapy.
Source: Journal of the Neurological Sciences - August 9, 2018 Category: Neurology Authors: Suman Kushwaha, Puneet Talwar, Niketa Chandel, Aldrin Anthony, Siddharth Maheshwari, Sarbjeet Khurana Source Type: research
Stroke risk associated with carotid and aortic atherosclerosis in patients with atrial fibrillation: A systematic review
This review aimed to summarize the evidence on the risk of thromboembolism associated with carotid and aortic atherosclerosis in patients with AF, and the potential impact of their inclusion in current stroke risk stratification scores.
Source: Journal of the Neurological Sciences - April 10, 2021 Category: Neurology Authors: Jean Jacques Noubiap, Joseph Kamtchum-Tatuene, John L. Fitzgerald, Prashanthan Sanders Tags: Review Article Source Type: research
Re: Semerano A, Mamadou Z, Desilles JP, Sabben C, Bacigaluppi M, Piotin M, et al. Carotid webs in large vessel occlusion stroke: Clinical, radiological and thrombus histopathological findings. Journal of the neurological sciences. 2021;427:117550
We read with interest the manuscript entitled “Carotid webs in large vessel occlusion stroke: Clinical, radiological and thrombus histopathological findings“by Semerano et al., which adds to the body of literature related to the treatment of carotid webs [1].
Source: Journal of the Neurological Sciences - August 20, 2021 Category: Neurology Authors: Diogo C. Haussen, Alhamza R. Al-Bayati, Nirav Bhatt, Raul G. Nogueira Tags: Letter to the Editor Source Type: research
Acute ischemic stroke and vaccine-induced immune thrombotic thrombocytopenia post COVID-19 vaccination; a systematic review
One of the rare but potentially serious side effects of COVID-19 vaccination is arterial and venous thrombosis. Acute ischemic stroke (AIS) cases have been reported post COVID-19 vaccination. Herein, we systematically reviewed the reported cases of AIS after COVID-19 vaccination.
Source: Journal of the Neurological Sciences - June 20, 2022 Category: Neurology Authors: Zahra Kolahchi, MohammadHossein Khanmirzaei, Ashkan Mowla Tags: Review Article Source Type: research
The ratio of d-dimer to brain natriuretic peptide may help to differentiate between cerebral infarction with and without acute aortic dissection
Conclusion: We found that the d-dimer:BNP ratio may be helpful in distinguishing between cerebral infarction with and without AAD.Highlights:
Source: Journal of the Neurological Sciences - March 20, 2014 Category: Neurology Authors: Toshiyuki Okazaki, Yoko Yamamoto, Keishi Yoda, Shinji Nagahiro Tags: Original Articles Source Type: research
A novel embolic middle cerebral artery occlusion model induced by thrombus formed in common carotid artery in rat
Stroke is a major cause of death and disability in the worldwide. However, treatment options to date are very limited. To meet the need for validating the novel therapeutic approaches and understanding the physiopathology of the ischemic brain injury, experimental stroke models were critical for preclinical research. However, commonly used embolic stroke models are reluctant to mimic the clinical situation and not suitable for thrombolytic timing studies. In this paper, we established a standard method for producing a rat embolic stroke model with autologous thrombus formed within common carotid artery (CCA) by constant galvanic stimulation.
Source: Journal of the Neurological Sciences - October 2, 2015 Category: Neurology Authors: Yin-Zhong Ma, Li Li, Jun-Ke Song, Zi-Ran Niu, Hai-Feng Liu, Xiang-Shan Zhou, Fu-Sheng Xie, Guan-Hua Du Source Type: research
Cerebral venous sinus thrombosis associated with SARS-CoV-2; a multinational case series
We present a series of CVST cases with SARS-CoV-2 infection.Methods In a multinational retrospective study, we collected all cases of CVST in SARS-CoV-2 infected patients admitted to nine tertiary stroke centers from the beginning of the pandemic to June 30th, 2020. We compared the demographics, clinical and radiological characteristics, risk factors, and outcome of these patients with a control group of non-SARS-CoV-2 infected CVST patients in the same seasonal period of the years 2012 –2016 from the country where the majority of cases were recruited.
Source: Journal of the Neurological Sciences - October 14, 2020 Category: Neurology Authors: Ashkan Mowla, Banafsheh Shakibajahromi, Shima Shahjouei, Afshin Borhani-Haghighi, Nasrin Rahimian, Humain Baharvahdat, Soheil Naderi, Fariborz Khorvash, Davar Altafi, Seyed Amir Ebrahimzadeh, Ghasem Farahmand, Alaleh Vaghefi Far, Vijay K. Sharma, Saeideh Source Type: research
Whipple's endocarditis diagnosed by thrombus analysis retrieved by successful mechanical thrombectomy
We report a case of Whipple Endocarditis leading to a proximal embolic stroke successfully treated by mechanical thrombectomy.
Source: Journal of the Neurological Sciences - March 13, 2019 Category: Neurology Authors: Ong Elodie, Paul-Emile Labeyrie, Matthieu Aubry, Delahaye Cecile, Sandrine Roux, Tristan Ferry, Norbert Nighoghossian Tags: Letter to the Editor Source Type: research
Impact of thrombus migration on clinical outcomes in patients with internal carotid artery occlusions and patent middle cerebral artery
Patency of the middle cerebral artery (MCA) in acute ischemic stroke with internal carotid artery (ICA) occlusions is associated with less severe stroke and favorable outcomes. However, thrombus migration to distal intracranial vessels may lead to unfavorable outcomes. We investigated the influence of thrombus migration on clinical outcomes in patients with ICA occlusions and patent MCA.
Source: Journal of the Neurological Sciences - February 14, 2020 Category: Neurology Authors: Junpei Koge, Shoji Matsumoto, Ichiro Nakahara, Akira Ishii, Taketo Hatano, Yujiro Tanaka, Daisuke Kondo, Jun-ichi Kira, Izumi Nagata Source Type: research
Acute recanalization and hyperperfusion in MCA territory due to sole t-PA bolus. A case report
Tissue plasminogen activator (t-PA) is the only approved thrombolytic therapy for the treatment of stroke patients. However, there is discussion whether the current dosing of t-PA (0.9mg/kg) is the optimal choice for all patients [1]. It is also unknown whether the duration of administration (1h) is being optimal. Moreover, there is no information available about the effectiveness of a sole t-PA bolus. The following case demonstrates effectiveness and importance of the bolus of t-PA.
Source: Journal of the Neurological Sciences - September 24, 2014 Category: Neurology Authors: Carsten M. Klingner, Stefan Brodoehl, Christian Hohenstein, Otto W. Witte, Albrecht Günther Tags: Letter to the editor Source Type: research
Post-thrombolysis haemostasis changes after rt-PA treatment in acute cerebral infarct. Correlations with cardioembolic etiology and outcome
: Little is known, in man, in the post-thrombolytic molecular dynamics of haemostasis, particularly the effect of rt-PA on antifibrinolytic components such as alpha2 anti-plasmin and Factor XIII. Aims and hypothesis: The purpose of this study was to systematically determine changes in coagulation and fibrinolytic parameters after thrombolysis with rt-PA during 24hours. We also aimed to correlate these parameters with different acute ischemic stroke subtypes and global outcome. Methods: Eighty consecutive patients with cerebral infarcts treated with rt-PA had their plasma levels of fibrinogen, plasminogen, alpha2-antiplasmi...
Source: Journal of the Neurological Sciences - December 29, 2014 Category: Neurology Authors: Xuhong Sun, Julien Berthiller, Laurent Derex, Paul Trouillas, Laho Diallo, Michel Hanss Source Type: research
Chronic kidney disease and intravenous thrombolysis in acute stroke: A systematic review and meta-analysis
The association between chronic kidney disease (CKD) and hemorrhagic complications or clinical outcomes in patients treated with intravenous (IV) thrombolytic agents is controversial.
Source: Journal of the Neurological Sciences - September 17, 2015 Category: Neurology Authors: Jin-Man Jung, Hyun Jung Kim, Hyeongsik Ahn, Il Min Ahn, Youngrok Do, Jeong-Yoon Choi, Woo-Keun Seo, Kyungmi Oh, Kyung-Hee Cho, Sungwook Yu Source Type: research
Stroke revealing Neuro-Beh çet's disease with parenchymal and extensive vascular involvement
The frequency of neurologic manifestations in Beh çet's disease (BD) ranges between 5% and 15% [1]. Central nervous system manifestations are represented by parenchymal involvement, which includes brainstem involvement, hemispheric manifestations, spinal cord lesions, and meningo-encephalitic presentations and non parenchymal involvement, includin g dural sinus thrombosis, arterial occlusion, and/or aneurysms. The association of parenchymal and vascular manifestations is extremely rare [2]. Among the neuro-vasculo-Behçet's disease patients, venous thrombosis is well-known while arterial involvement has rarely been report...
Source: Journal of the Neurological Sciences - January 26, 2019 Category: Neurology Authors: Nouha Hamza, Samia Ben Sassi, Fatma Nabli, Sonia Nagi, Maha Mahmoud, Ines Ben Abdelaziz, Fay çal Hentati Tags: Letter to the Editor Source Type: research
Elevated fasting blood glucose is predictive of the severity and poor outcome in nondiabetic patients with cerebral venous thrombosis
Although elevated fasting blood glucose (FBG) at admission is associated with poor outcome in patients with ischemic and hemorrhagic stroke, it has not been investigated in patients with cerebral venous thrombosis (CVT). We aimed to determine the correlation between elevated FBG and severity and outcome among CVT patients.
Source: Journal of the Neurological Sciences - July 15, 2020 Category: Neurology Authors: Yating Wu, Lixin Zhou, Ming Yao, Yicheng Zhu, Jun Ni, Liying Cui, Bin Peng Source Type: research
Cerebral thrombi of cardioembolic etiology have an increased content of neutrophil extracellular traps
Inflammation is emerging as an essential trigger for thrombosis. In the interplay between innate immunity and coagulation cascade, neutrophils and neutrophil extracellular traps (NETs) can promote thrombus formation and stabilization. In ischemic stroke, it is uncertain whether the involvement of the inflammatory component may differ in thrombi of diverse etiology. We here aimed to evaluate the presence of neutrophils and NETs in thrombi of diverse etiology retrieved by endovascular thrombectomy (EVT).
Source: Journal of the Neurological Sciences - February 21, 2021 Category: Neurology Authors: Angela Genchi, Aurora Semerano, Giorgia Serena Gullotta, Davide Strambo, Ghil Schwarz, Andrea Bergamaschi, Pietro Panni, Franco Simionato, Francesco Scomazzoni, Caterina Michelozzi, Mattia Pozzato, Norma Maugeri, Giancarlo Comi, Andrea Falini, Luisa Rover Source Type: research
