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Periprocedural Safety and Feasibility of the New LVIS EVO Device for Stent-Assisted Coiling of Intracranial Aneurysms: An Observational Multicenter Study INTERVENTIONAL
CONCLUSIONS: The LVIS EVO stent is a safe, feasible device for the treatment of intracranial aneurysms.
Source: American Journal of Neuroradiology - February 9, 2021 Category: Radiology Authors: Vollherbst, D. F., Berlis, A., Maurer, C., Behrens, L., Sirakov, S., Sirakov, A., Fischer, S., Maus, V., Holtmannspötter, M., Rautio, R., Sinisalo, M., Poncyljusz, W., Janssen, H., Wodarg, F., Kabbasch, C., Trenkler, J., Herweh, C., Bendszus, M., Tags: INTERVENTIONAL Source Type: research

Clot Burden Score and Collateral Status and Their Impact on Functional Outcome in Acute Ischemic Stroke ADULT BRAIN
CONCLUSIONS: The association between the clot burden score and functional outcome varied for different collateral scores. The FLAIR vascular hyperintensity score might be a valuable prognostic factor, especially when contrast-based vascular imaging is not available.
Source: American Journal of Neuroradiology - January 11, 2021 Category: Radiology Authors: Derraz, I., Pou, M., Labreuche, J., Legrand, L., Soize, S., Tisserand, M., Rosso, C., Piotin, M., Boulouis, G., Oppenheim, C., Naggara, O., Bracard, S., Clarencon, F., Lapergue, B., Bourcier,, R., on behalf of the ASTER and the THRACE Trials Investigators Tags: ADULT BRAIN Source Type: research

Characteristics of Large-Vessel Occlusion Associated with COVID-19 and Ischemic Stroke INTERVENTIONAL
SUMMARY: The mechanisms and phenotype of ischemic stroke associated with coronavirus disease 2019 (COVID-19) remain uncertain. A retrospective study was conducted in patients with COVID-19 presenting with ischemic stroke from March 1 to May 25, 2020, and cases with large-vessel occlusion were identified. To provide baseline institutional stroke data within and outside the COVID-19 pandemic, all consecutive ischemic stroke and TIA admissions (COVID and non-COVID) to the hospital during a 10-week period from March 1 to May 10, 2020, were collected and compared with data from the same time period in 2019. Among 20 patients wi...
Source: American Journal of Neuroradiology - December 11, 2020 Category: Radiology Authors: John, S., Kesav, P., Mifsud, V. A., Piechowski-Jozwiak, B., Dibu, J., Bayrlee, A., Elkambergy, H., Roser, F., Elhammady, M. S., Zahra, K., Hussain, S. I. Tags: INTERVENTIONAL Source Type: research

Perinatal Arterial Ischemic Stroke in Fetal Vascular Malperfusion: A Case Series and Literature Review PEDIATRICS
SUMMARY: Fetal vascular malperfusion includes a continuum of placental histologic abnormalities increasingly associated with perinatal brain injury, namely arterial ischemic stroke. Here, we describe the clinical-neuroimaging features of 5 neonates with arterial ischemic stroke and histologically proved fetal vascular malperfusion. All infarcts involved the anterior territories and were multiple in 2 patients. In 2 neonates, there were additional signs of marked dural sinus congestion, thrombosis, or both. A mixed pattern of chronic hypoxic-ischemic encephalopathy and acute infarcts was noted in 1 patient at birth. Systemi...
Source: American Journal of Neuroradiology - December 11, 2020 Category: Radiology Authors: Geraldo, A. F., Parodi, A., Bertamino, M., Buffelli, F., Uccella, S., Tortora, D., Moretti, P., Ramenghi, L., Fulcheri, E., Rossi, A., Severino, M. Tags: PEDIATRICS Source Type: research

COVID-19-Associated Carotid Atherothrombosis and Stroke EXTRACRANIAL VASCULAR
We present a radiology-pathology case series of 3 patients with coronavirus disease 2019 (COVID-19) with acute ischemic stroke due to fulminant carotid thrombosis overlying mild atherosclerotic plaque and propose a novel stroke mechanism: COVID-associated carotid atherothrombosis.
Source: American Journal of Neuroradiology - November 11, 2020 Category: Radiology Authors: Esenwa, C., Cheng, N. T., Lipsitz, E., Hsu, K., Zampolin, R., Gersten, A., Antoniello, D., Soetanto, A., Kirchoff, K., Liberman, A., Mabie, P., Nisar, T., Rahimian, D., Brook, A., Lee, S.- K., Haranhalli, N., Altschul, D., Labovitz, D. Tags: EXTRACRANIAL VASCULAR Source Type: research

Intraluminal Carotid Artery Thrombus in COVID-19: Another Danger of Cytokine Storm? EXTRACRANIAL VASCULAR
We report a series of 6 patients with COVID-19 with acute ischemic stroke due to intraluminal carotid artery thrombus presenting during an 8-day period. Six patients were included (5 men) with a mean age of 65.8 years (range, 55–78 years). COVID-19 was diagnosed by detection of Severe Acute Respiratory Syndrome coronavirus 2 in 5 patients and was presumed due to typical clinical and imaging findings in 1 patient. All patients had vascular risk factors including diabetes (83%), hyperlipidemia (100%), and smoking (17%). Four patients presented with large infarcts with initial NIHSS scores of 24–30. During their h...
Source: American Journal of Neuroradiology - September 8, 2020 Category: Radiology Authors: Mohamud, A. Y., Griffith, B., Rehman, M., Miller, D., Chebl, A., Patel, S. C., Howell, B., Kole, M., Marin, H. Tags: EXTRACRANIAL VASCULAR Source Type: research

White Matter Disease and Outcomes of Mechanical Thrombectomy for Acute Ischemic Stroke INTERVENTIONAL
CONCLUSIONS: Moderate-to-severe white matter disease is associated with worse outcomes in patients undergoing endovascular treatment without a significant increase in hemorrhagic complications. Studies comparing patients with and without endovascular treatment are necessary to determine whether the benefit of endovascular treatment is attenuated with greater white matter disease.
Source: American Journal of Neuroradiology - April 8, 2020 Category: Radiology Authors: Mistry, E. A., Mistry, A. M., Mehta, T., Arora, N., Starosciak, A. K., La Rosa, F. D. L. R., Siegler, J. E., Kasner, S. E., Chitale, R., Fusco, M., Froehler, M., Yaghi, S., Schrag, M., Khatri, P., on behalf of BEST Collaborators Tags: INTERVENTIONAL Source Type: research

Is Histologic Thrombus Composition in Acute Stroke Linked to Stroke Etiology or to Interventional Parameters? INTERVENTIONAL
CONCLUSIONS: We interpreted the higher macrophage and platelet content in cardioembolic thrombi compared with large-artery atherosclerotic stenosis or embolic stroke of undetermined source thrombi as an indication that the latter type might be derived from an atherosclerotic plaque rather than from an undetermined cardiac source. The extent of thrombus fragmentation was associated with a more challenging mechanical thrombectomy and a higher lymphocyte content of the thrombi. Thus, thrombus fragmentation not only might be caused by the recanalization procedure but also might be a feature of a lymphocyte-rich, difficult-to-r...
Source: American Journal of Neuroradiology - April 8, 2020 Category: Radiology Authors: Goebel, J., Gaida, B.- J., Wanke, I., Kleinschnitz, C., Koehrmann, M., Forsting, M., Moenninghoff, C., Radbruch, A., Junker, A. Tags: INTERVENTIONAL Source Type: research

Endovascular Thrombectomy of Calcified Emboli in Acute Ischemic Stroke: A Multicenter Study INTERVENTIONAL
CONCLUSIONS: Acute ischemic stroke with large-vessel occlusion due to calcified emboli is a rare entity in patients undergoing thrombectomy, with considerably worse angiographic outcome and a higher mortality compared with patients with noncalcified thrombi. Good functional recovery at 3 months can still be achieved in about a quarter of patients.
Source: American Journal of Neuroradiology - March 16, 2020 Category: Radiology Authors: Maurer, C. J., Dobrocky, T., Joachimski, F., Neuberger, U., Demerath, T., Brehm, A., Cianfoni, A., Gory, B., Berlis, A., Gralla, J., Möhlenbruch, M. A., Blackham, K. A., Psychogios, M. N., Zickler, P., Fischer, S. Tags: INTERVENTIONAL Source Type: research

Flow Patterns in Carotid Webs: A Patient-Based Computational Fluid Dynamics Study EXTRACRANIAL VASCULAR
CONCLUSIONS: Carotid webs are associated with increased recirculation zones and regional increased wall shear stress metrics that are associated with disturbed flow. These findings suggest that a carotid web might stimulate thrombus formation, which increases the risk of acute ischemic stroke.
Source: American Journal of Neuroradiology - April 10, 2019 Category: Radiology Authors: Compagne, K. C. J., Dilba, K., Postema, E. J., van Es, A. C. G. M., Emmer, B. J., Majoie, C. B. L. M., van Zwam, W. H., Dippel, D. W. J., Wentzel, J. J., van der Lugt, A., Gijsen, F. J. H., for the MR CLEAN investigators Tags: EXTRACRANIAL VASCULAR Source Type: research

Predictors and Clinical Impact of Delayed Stent Thrombosis after Thrombectomy for Acute Stroke with Tandem Lesions INTERVENTIONAL
CONCLUSIONS: We observed a non-negligible rate of delayed stent thrombosis with significant negative impact on clinical outcome. Future studies should systematically measure and report stent patency rates.
Source: American Journal of Neuroradiology - March 13, 2019 Category: Radiology Authors: Pop, R., Zinchenko, I., Quenardelle, V., Mihoc, D., Manisor, M., Richter, J. S., Severac, F., Simu, M., Chibbaro, S., Rouyer, O., Wolff, V., Beaujeux, R. Tags: INTERVENTIONAL Source Type: research

Radiomics-Based Intracranial Thrombus Features on CT and CTA Predict Recanalization with Intravenous Alteplase in Patients with Acute Ischemic Stroke FUNCTIONAL
CONCLUSIONS: Thrombus radiomics features derived from NCCT and CTA are more predictive of recanalization with IV alteplase in patients with acute ischemic stroke with proximal occlusion than previously known thrombus imaging features such as length, volume, and permeability.
Source: American Journal of Neuroradiology - January 11, 2019 Category: Radiology Authors: Qiu, W., Kuang, H., Nair, J., Assis, Z., Najm, M., McDougall, C., McDougall, B., Chung, K., Wilson, A. T., Goyal, M., Hill, M. D., Demchuk, A. M., Menon, B. K. Tags: FUNCTIONAL Source Type: research

MRI Quantitative T2* Mapping to Predict Dominant Composition of In Vitro Thrombus ADULT BRAIN
CONCLUSIONS: MR imaging quantitative T2* mapping can reliably identify the thrombus red blood cell content in vitro. This fast, easy-to-use sequence could be implemented in routine practice to predict stroke etiology and adapt devices or techniques for endovascular treatment of acute ischemic stroke.
Source: American Journal of Neuroradiology - January 11, 2019 Category: Radiology Authors: Bourcier, R., Pautre, R., Mirza, M., Castets, C., Darcourt, J., Labreuche, J., Detraz, L., Desal, H., Serfaty, J.- M., Toquet, C. Tags: ADULT BRAIN Source Type: research

Thrombus Permeability on Dynamic CTA Predicts Good Outcome after Reperfusion Therapy INTERVENTIONAL
CONCLUSIONS: Thrombus permeability assessed on dynamic CTA could be a better predictor of outcome after reperfusion therapy than that assessed on conventional single-phase CTA.
Source: American Journal of Neuroradiology - October 8, 2018 Category: Radiology Authors: Chen, Z., Shi, F., Gong, X., Zhang, R., Zhong, W., Zhang, R., Zhou, Y., Lou, M. Tags: INTERVENTIONAL Source Type: research

Mobile Stroke Unit Reduces Time to Image Acquisition and Reporting INTERVENTIONAL
SUMMARY: Timely administration of thrombolytic therapy is critical to maximizing the likelihood of favorable outcomes in patients with acute ischemic stroke. Although emergency medical service activation overall improves the timeliness of acute stroke treatment, the time from emergency medical service dispatch to hospital arrival unavoidably decreases the timeliness of thrombolytic administration. Our mobile stroke unit, a new-generation ambulance with on-board CT scanning capability, reduces key imaging time metrics and facilitates in-the-field delivery of IV thrombolytic therapy.
Source: American Journal of Neuroradiology - July 9, 2018 Category: Radiology Authors: Nyberg, E. M., Cox, J. R., Kowalski, R. G., Vela-Duarte, D., Schimpf, B., Jones, W. J. Tags: INTERVENTIONAL Source Type: research

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