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Source: American Journal of Neuroradiology
Condition: Thrombosis

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Total 63 results found since Jan 2013.

Whole-Brain Susceptibility-Weighted Thrombus Imaging in Stroke: Fragmented Thrombi Predict Worse Outcome ADULT BRAIN
CONCLUSIONS: Patients with multiple intracranial thrombus fragments constitute a small subgroup of patients with stroke with a worse outcome than patients with single thrombi.
Source: American Journal of Neuroradiology - July 15, 2015 Category: Radiology Authors: Gratz, P. P., Schroth, G., Gralla, J., Mattle, H. P., Fischer, U., Jung, S., Mordasini, P., Hsieh, K., Verma, R. K., Weisstanner, C., El-Koussy, M. Tags: ADULT BRAIN Source Type: research

Endovascular Recanalization in Acute Ischemic Stroke Using the Solitaire FR Revascularization Device with Adjunctive C-Arm CT Imaging INTERVENTIONAL
SUMMARY: In this clinical report, we examined a single-center experience by using the Solitaire FR Revascularization Device in the treatment of acute ischemic stroke in which there was poor initial visualization of the occluded arterial branches by using biplanar cerebral angiography. In all cases, adjunctive C-arm CT was used during the deployment of the thrombectomy device to gain additional information regarding device placement and expansion. Outcome measures included the extent of reperfusion, posttreatment changes in NIHSS scores, posttreatment TICI scores, cerebral hemorrhage, and survival. Clot removal with success...
Source: American Journal of Neuroradiology - July 15, 2015 Category: Radiology Authors: Mitchell, B. D., Chinnadurai, P., Chintalapani, G., Morsi, H. A., Shaltoni, H., Mawad, M. E. Tags: INTERVENTIONAL Source Type: research

4D-CTA in Neurovascular Disease: A Review REVIEW ARTICLES
This article provides a description of 4D-CTA techniques and a review of the available literature on the application of 4D-CTA for the evaluation of intracranial vascular malformations and hemorrhagic and ischemic stroke. Most of the research performed to date consists of observational cohort studies or descriptive case series. These studies show that intracranial vascular malformations can be adequately depicted and classified by 4D-CTA, with DSA as the reference standard. In ischemic stroke, 4D-CTA better estimates thrombus burden and the presence of collateral vessels than conventional CTA. In intracranial hemorrhage, 4...
Source: American Journal of Neuroradiology - June 11, 2015 Category: Radiology Authors: Kortman, H. G. J., Smit, E. J., Oei, M. T. H., Manniesing, R., Prokop, M., Meijer, F. J. A. Tags: REVIEW ARTICLES Source Type: research

Predictors of Reperfusion in Patients with Acute Ischemic Stroke BRAIN
CONCLUSIONS: Recanalization and reperfusion are strongly associated but not always equivalent in ischemic stroke. A smaller total ischemic area is the only independent predictor of complete reperfusion.
Source: American Journal of Neuroradiology - June 11, 2015 Category: Radiology Authors: Horsch, A. D., Dankbaar, J. W., Niesten, J. M., van Seeters, T., van der Schaaf, I. C., van der Graaf, Y., Mali, W. P. T. M., Velthuis, B. K., on behalf of the Dutch Acute Stroke Study Investigators Tags: BRAIN Source Type: research

The Curved MCA: Influence of Vessel Anatomy on Recanalization Results of Mechanical Thrombectomy after Acute Ischemic Stroke INTERVENTIONAL
CONCLUSIONS: This retrospective analysis showed that mechanical thrombectomy in the anterior circulation was significantly less often successful in patients with large vessel angles. Therefore, vessel curvature significantly influences the results of mechanical thrombectomy with stent retrievers for treatment of acute ischemic stroke. Further work is needed to understand the underlying causality.
Source: American Journal of Neuroradiology - May 15, 2015 Category: Radiology Authors: Schwaiger, B. J., Gersing, A. S., Zimmer, C., Prothmann, S. Tags: INTERVENTIONAL Source Type: research

Rescue Treatment of Thromboembolic Complications during Endovascular Treatment of Cerebral Aneurysms: A Meta-Analysis FELLOWS' JOURNAL CLUB
CONCLUSIONS: Rescue therapy with thrombolytic agents resulted in significantly more morbidity than rescue therapy with glycoprotein IIb/IIIa inhibitors. Tirofiban/eptifibatide resulted in significantly higher recanalization rates compared with abciximab.
Source: American Journal of Neuroradiology - January 13, 2015 Category: Radiology Authors: Brinjikji, W., Morales-Valero, S. F., Murad, M. H., Cloft, H. J., Kallmes, D. F. Tags: FELLOWS ' JOURNAL CLUB Source Type: research

Susceptibility-Diffusion Mismatch Predicts Thrombolytic Outcomes: A Retrospective Cohort Study FELLOWS' JOURNAL CLUB
CONCLUSIONS: The presence of SWI-DWI mismatch may identify patients with ischemia who would benefit from early reperfusion therapy.
Source: American Journal of Neuroradiology - November 14, 2014 Category: Radiology Authors: Lou, M., Chen, Z., Wan, J., Hu, H., Cai, X., Shi, Z., Sun, J. Tags: FELLOWS ' JOURNAL CLUB Source Type: research

Collateral Score Complements Clot Location in Predicting the Outcome of Intravenous Thrombolysis BRAIN
CONCLUSIONS: A proximal occlusion in the anterior circulation is associated with poorer collateral status compared with a more distal occlusion. Both the clot location and collateral score are important and independent predictors of favorable clinical outcome of hyperacute stroke treated with intravenous thrombolysis. The location of the clot is a stronger determinant of the outcome than the collateral score.
Source: American Journal of Neuroradiology - October 8, 2014 Category: Radiology Authors: Saarinen, J. T., Rusanen, H., Sillanpaa, N. Tags: BRAIN Source Type: research

Imaging and Treatment of Patients with Acute Stroke: An Evidence-Based Review REVIEW ARTICLES
SUMMARY: Evidence-based medicine has emerged as a valuable tool to guide clinical decision-making, by summarizing the best possible evidence for both diagnostic and treatment strategies. Imaging plays a critical role in the evaluation and treatment of patients with acute ischemic stroke, especially those who are being considered for thrombolytic or endovascular therapy. Time from stroke-symptom onset to treatment is a strong predictor of long-term functional outcome after stroke. Therefore, imaging and treatment decisions must occur rapidly in this setting, while minimizing unnecessary delays in treatment. The aim of this ...
Source: American Journal of Neuroradiology - June 11, 2014 Category: Radiology Authors: Sanelli, P. C., Sykes, J. B., Ford, A. L., Lee, J.- M., Vo, K. D., Hallam, D. K. Tags: REVIEW ARTICLES Source Type: research

Pretreatment Advanced Imaging in Patients with Stroke Treated with IV Thrombolysis: Evaluation of a Multihospital Data Base BRAIN
CONCLUSIONS: Use of advanced imaging is increasing in patients treated with IV thrombolysis. While there were differences in outcomes among imaging groups, the clinical effect of advanced imaging remains unclear.
Source: American Journal of Neuroradiology - March 13, 2014 Category: Radiology Authors: McDonald, J. S., Fan, J., Kallmes, D. F., Cloft, H. J. Tags: BRAIN Source Type: research

Potential for the Use of the Solitaire Stent for Recanalization of Middle Cerebral Artery Occlusion without a Susceptibility Vessel Sign INTERVENTIONAL
CONCLUSIONS: The Solitaire stent is a feasible tool as the first-line device for multimodal endovascular recanalization therapy in acute ischemic stroke with a negative MCA susceptibility vessel sign. It has a good rate of successful and complete recanalization and is a fast yet safe procedure.
Source: American Journal of Neuroradiology - January 13, 2014 Category: Radiology Authors: Bae, Y. J., Jung, C., Kim, J. H., Choi, B. S., Kim, E., Han, M.- K., Bae, H.- J., Han, M. H. Tags: INTERVENTIONAL Source Type: research

CTA for Screening of Complicated Atherosclerotic Carotid Plaque--American Heart Association Type VI Lesions as Defined by MRI EXTRACRANIAL VASCULAR
CONCLUSIONS: Maximum soft plaque component thickness as measured by carotid CTA is a reliable indicator of a complicated plaque, with a threshold of 2.2 mm representing little to no probability of a complicated American Heart Association lesion type VI plaque.
Source: American Journal of Neuroradiology - December 13, 2013 Category: Radiology Authors: Trelles, M., Eberhardt, K. M., Buchholz, M., Schindler, A., Bayer-Karpinska, A., Dichgans, M., Reiser, M. F., Nikolaou, K., Saam, T. Tags: EXTRACRANIAL VASCULAR Source Type: research

Thrombus Attenuation Does Not Predict Angiographic Results of Mechanical Thrombectomy with Stent Retrievers FELLOWS' JOURNAL CLUB
CONCLUSIONS: In contrast to results of other revascularization procedures as published in a recent study, the angiographic result of mechanical thrombectomy with stent retrievers is not predicted by thrombus attenuation.
Source: American Journal of Neuroradiology - November 15, 2013 Category: Radiology Authors: Yilmaz, U., Roth, C., Reith, W., Papanagiotou, P. Tags: FELLOWS ' JOURNAL CLUB Source Type: research

Histopathologic Evaluation of Arterial Wall Response to 5 Neurovascular Mechanical Thrombectomy Devices in a Swine Model INTERVENTIONAL
CONCLUSIONS: All devices caused vascular injuries extending into the medial layer. The aspiration device was associated with more intimal and medial layer edema, compared with the wall-contact devices except for the Catch thromboembolectomy system.
Source: American Journal of Neuroradiology - November 15, 2013 Category: Radiology Authors: Gory, B., Bresson, D., Kessler, I., Perrin, M. L., Guillaudeau, A., Durand, K., Ponsonnard, S., Couquet, C., Yardin, C., Mounayer, C. Tags: INTERVENTIONAL Source Type: research

4D CT Angiography More Closely Defines Intracranial Thrombus Burden Than Single-Phase CT Angiography BRAIN
CONCLUSIONS: As the result of an increased sensitivity for collateral flow, 4D-CTA temporal maximum intensity projection more closely outlines intracranial thrombi than conventional single-phase CT angiography. Our findings can be helpful when planning acute neurointervention. Further research is necessary to validate our data and assess the use of 4D-CTA in predicting response to different recanalization strategies.
Source: American Journal of Neuroradiology - October 8, 2013 Category: Radiology Authors: Frolich, A. M. J., Schrader, D., Klotz, E., Schramm, R., Wasser, K., Knauth, M., Schramm, P. Tags: BRAIN Source Type: research