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Pneumonia, thrombosis and vascular disease
SummaryAn enhanced risk of cardiovascular mortality has been observed after pneumonia. Epidemiological studies have shown that respiratory tract infections are associated with an increased risk of thrombotic‐related vascular disease such as myocardial infarction, ischemic stroke and venous thrombosis. Myocardial infarction and stroke have been detected essentially in the early phase of the disease (i.e. within 48 h from hospital admission), with an incidence ranging from as low as 1% to as high as 11%. Age, previous cardiovascular events and high pneumonia severity index were independent predictors of myocardial infarct...
Source: Journal of Thrombosis and Haemostasis - July 23, 2014 Category: Hematology Authors: F. Violi, R. Cangemi, C. Calvieri Tags: Review Article Source Type: research

Pneumonia, thrombosis and vascular disease.
This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - June 1, 2014 Category: Hematology Authors: Francesco Violi, Roberto Cangemi, Camilla Calvieri Tags: Review Article Source Type: research

Increased platelet activation in early symptomatic vs. asymptomatic carotid stenosis and relationship with microembolic status: results from the Platelets and Carotid Stenosis Study
DiscussionRecently, symptomatic carotid stenosis patients have had higher platelet counts (potentially reflecting increased platelet production, mobilization or reduced clearance) and platelet activation status than asymptomatic patients. MES were more frequently detected in early symptomatic than asymptomatic patients, but the differences between late symptomatic and asymptomatic groups were not significant. Increased lymphocyte‐platelet complex formation in recently symptomatic vs. asymptomatic MES‐negative patients indicates enhanced platelet activation in this early symptomatic subgroup. Platelet biomarkers, in com...
Source: Journal of Thrombosis and Haemostasis - July 15, 2013 Category: Hematology Authors: J. A. Kinsella, W. O. Tobin, S. Tierney, T. M. Feeley, B. Egan, D. R. Collins, T. Coughlan, D. O'Neill, J. Harbison, P. Madhavan, D. J. Moore, S. M. O'Neill, M. P. Colgan, C. P. Doherty, R. P. Murphy, M. Saqqur, N. Moran, G. Hamilton, D. J. H McCabe Tags: Original Article Source Type: research

Increased platelet activation in early symptomatic versus asymptomatic carotid stenosis and relationship with microembolic status: Results from the Platelets And Carotid Stenosis (PACS) Study
This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - April 26, 2013 Category: Hematology Authors: JA Kinsella, WO Tobin, S Tierney, TM Feeley, B Egan, DR Collins, T Coughlan, D O'Neill, J Harbison, P Madhavan, DJ Moore, SM O'Neill, MP Colgan, CP Doherty, RP Murphy, M Saqqur, N Moran, G Hamilton, DJH McCabe Tags: Original Article ‐ Platelets Source Type: research

Cardiovascular mortality due to pulmonary embolism in subjects with renal impairment: patients’ comorbidities are crucial
Abstract we read with great interest the paper by Ocak et al. (1). The authors found that the age‐ and sex‐standardized mortality rate (SMR) for pulmonary embolism (PE) was 12.2 (95% CI 10.2‐14.6) times higher in dialysis patients than in the general population. Such SMR was even higher than that of myocardial infarction (MI) (11.0, 95% CI 10.6‐11.4), stroke (8.4 (95% CI 8.0‐8.8), and other cardiovascular disease (8.3, 95% CI 8.0‐8.5) On the one hand, the association between the different grade of impaired renal function and MI received important confirmation (2), and also a recent study from our group conducte...
Source: Journal of Thrombosis and Haemostasis - April 4, 2013 Category: Hematology Authors: Fabio Fabbian, Francesco Dentali, Walter Ageno, Roberto Manfredini Tags: Letter Rebuttal Source Type: research