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Condition: Thrombosis
Countries: Taiwan Health
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Total 317 results found since Jan 2013.
Monogenic Causes in Familial Stroke Across Intracerebral Hemorrhage and Ischemic Stroke Subtypes Identified by Whole-Exome Sequencing
Cell Mol Neurobiol. 2022 Dec 29. doi: 10.1007/s10571-022-01315-3. Online ahead of print.ABSTRACTWhole exome sequencing (WES) has been used to detect rare causative variants in neurological diseases. However, the efficacy of WES in genetic diagnosis of clinically heterogeneous familial stroke remains inconclusive. We prospectively searched for disease-causing variants in unrelated probands with defined familial stroke by candidate gene/hotspot screening and/or WES, depending on stroke subtypes and neuroimaging features at a referral center. The clinical significance of each variant was determined according to the American C...
Source: Cellular and Molecular Neurobiology - December 29, 2022 Category: Cytology Authors: Li-Hsin Chang Nai-Fang Chi Chun-Yu Chen Yung-Shuan Lin Shao-Lun Hsu Jui-Yao Tsai Hui-Chi Huang Chun-Jen Lin Chih-Ping Chung Chien-Yi Tung Chung-Jiuan Jeng Yi-Chung Lee Yo-Tsen Liu I-Hui Lee Source Type: research
Update of Intravenous Thrombolytic Therapy in Acute Ischemic Stroke
Acta Neurol Taiwan. 2021 Jun 30;30(2):44-53.ABSTRACTUpon acute ischemic stroke, rapid recanalization of the occluded cerebral vessel via intravenous thrombolytic therapy (IVT) is crucial to achieve good functional outcome. The time window of IVT with recombinant tissue plasminogen activator (rt-PA) has been extended from post-stroke 3 to 4.5 hours. In patients with cerebral penumbra identified using cerebral perfusion imaging, IVT is still beneficial within 4.5 to 9 hours after onset of stroke. For those without clear stroke onset time, DWI-FLAIR mismatch by brain MRI indicates hyperacute infarct and IVT is indicative. For...
Source: Acta Neurologica Taiwanica - September 22, 2021 Category: Neurology Authors: Li-Kai Tsai Jiann-Shing Jeng Source Type: research
