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Anticoagulation use in perioperative atrial fibrillation after noncardiac surgery: a systematic review and meta-analysis
CONCLUSION: Anticoagulation is associated with a reduced risk of stroke and death but an increased risk of bleeding. The quality of the evidence is very poor. Randomised trials are needed to better determine the effects of anticoagulation use in this population.PMID:37080190 | DOI:10.57187/smw.2023.40056
Source: Swiss Medical Weekly - April 20, 2023 Category: General Medicine Authors: Michael Ke Wang Rachel Heo Pascal B Meyre Steffen Blum Louis Park Lauren Birchenough Kiven Vuong William F McIntyre Jeff S Healey Philip J Devereaux Michael McMullen Marko Mrkobrada Natalia Pinilla-Echeverri Kim Styles David Conen Source Type: research

Cardiovascular disease after childhood acute lymphoblastic leukaemia: a cohort study.
CONCLUSIONS: Despite attempts to reduce cardiotoxicity in childhood cancer treatment, CVD risks in ALL survivors treated more recently do not seem to have declined. PMID: 30852834 [PubMed - in process]
Source: Swiss Medical Weekly - February 24, 2019 Category: General Medicine Authors: Hau EM, Caccia JN, Kasteler R, Spycher B, Suter T, Ammann RA, von der Weid NX, Kuehni CE Tags: Swiss Med Wkly Source Type: research

Direct oral anticoagulants in the elderly: systematic review and meta-analysis of evidence, current and future directions.
CONCLUSION: DOACs show the same or greater efficacy than vitamin K antagonists in elderly patients with atrial fibrillation and VTE. Individual differences between DOACs in terms of safety profile cannot be excluded on the basis of current evidence. Direct head-to-head comparisons are needed to investigate possible divergence in pharmacological profiles between DOACs. Additionally, further studies conducted in real-word settings and in the frail elderly are ongoing and it would be interesting to target this particular patient group. PMID: 27683276 [PubMed - as supplied by publisher]
Source: Swiss Medical Weekly - October 1, 2016 Category: Journals (General) Authors: Sadlon AH, Tsakiris DA Tags: Swiss Med Wkly Source Type: research