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Patent Foramen Ovale, Subclinical Cerebrovascular Disease, and Ischemic Stroke in a Population-Based Cohort
Conclusions: In this community-based cohort, PFO was not associated with an increased risk of clinical stroke or subclinical cerebrovascular disease.
Source: Journal of the American College of Cardiology - May 3, 2013 Category: Cardiology Authors: Marco R. Di Tullio, Zhezhen Jin, Cesare Russo, Mitchell S.V. Elkind, Tatjana Rundek, Mitsuhiro Yoshita, Charles DeCarli, Clinton B. Wright, Shunichi Homma, Ralph L. Sacco Tags: Patent Foramen Ovale and Stroke Source Type: research

Carotid Artery Free-Floating Thrombus Caused by Paradoxical Embolization From Greater Saphenous Vein Ascending Thrombophlebitis
We report a case of a young woman without cardiovascular risk factors who was admitted to our emergency department with listlessness and altered mental status. The clinical examination revealed right lower limb swelling. Magnetic resonance imaging and contrast-enhanced computed tomographic scans revealed a free floating thrombus of the left internal carotid artery (ICA) with a large bilateral frontal ischemic lesion. The diagnosis of a medium-sized PFO with moderate right-to-left contrast shunting was made after transesophageal echocardiography. No other cardiac sources for embolization were detected, while an ascending th...
Source: Annals of Vascular Surgery - April 28, 2013 Category: Surgery Authors: Luigi Irace, Roberto Gabrielli, Maria Sofia Rosati, Maria Fabrizia Giannoni, Anna Castiglione, Antonella Laurito, Bruno Gossetti Tags: Case Report Abstracts Source Type: research

Neuroimaging Findings in Cryptogenic Stroke Patients With and Without Patent Foramen Ovale Clinical Sciences
Conclusions— This is the largest study to report the radiological characteristics of patients with cryptogenic stroke and known PFO status. Strokes that were large, radiologically apparent, superficially located, or unassociated with prior radiological infarcts were more likely to be PFO-associated than were unapparent, smaller, or deep strokes, and those accompanied by chronic infarcts. There was no association between PFO and multiple acute strokes nor between specific echocardiographic PFO features with neuroimaging findings.
Source: Stroke - February 25, 2013 Category: Neurology Authors: Thaler, D. E., Ruthazer, R., Di Angelantonio, E., Di Tullio, M. R., Donovan, J. S., Elkind, M. S. V., Griffith, J., Homma, S., Jaigobin, C., Mas, J.-L., Mattle, H. P., Michel, P., Mono, M.-L., Nedeltchev, K., Papetti, F., Serena, J., Weimar, C., Kent, D. Tags: Cerebrovascular disease/stroke, Pediatric and congenital heart disease, including cardiovascular surgery, Computerized tomography and Magnetic Resonance Imaging, Risk Factors for Stroke Clinical Sciences Source Type: research

Systemic thrombolysis for stroke in pregnancy
Pregnancy is an exclusion criterion for all clinical trials that validate alteplase in acute stroke, so our knowledge about its use in this condition is relative only to case reports and case series. Herein, we report the successful use of intravenous recombinant tissue-type plasminogen activator (rt-PA) in pregnant women with acute stroke. The patient was a 28-year-old who was 16 weeks pregnant. She presented to our hospital 1 hour after a sudden onset of mothor aphasia, hemiparesis, and hypoesthesia on the right side due to incipient ischemia in the left cerebral hemisphere resulting from ipsilateral middle cerebral arte...
Source: The American Journal of Emergency Medicine - August 6, 2012 Category: Emergency Medicine Authors: Rossana Tassi, Maurizio Acampa, Giovanna Marotta, Samuele Cioni, Francesca Guideri, Simone Rossi, Alfonso Cerase, Giuseppe Martini Tags: Case Reports Source Type: research

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