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Source: Journal of Stroke and Cerebrovascular Diseases
Condition: Patent Foramen Ovale
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Total 46 results found since Jan 2013.
Risk Factor and Etiology Analysis of Ischemic Stroke in Young Adult Patients
Conclusions: Traditional vascular risk factors are also very common in young adults with ischemic stroke, but such factors increase the susceptibility to stroke dependent to other causes as atherosclerosis and small-artery occlusion represent less than 20% of cases. Prognosis quoadvitam is good, being characterized by low mortality and recurrence rate.
Source: Journal of Stroke and Cerebrovascular Diseases - January 13, 2014 Category: Neurology Authors: Rosaria Renna, Fabio Pilato, Paolo Profice, Giacomo Della Marca, Aldobrando Broccolini, Roberta Morosetti, Giovanni Frisullo, Elena Rossi, Valerio De Stefano, Vincenzo Di Lazzaro Tags: Original Articles Source Type: research
Migraine Improves after Ischemic Stroke
Objective: To assess if migraine frequency spontaneously changes after stroke.Background: Patent foramen ovale (PFO) closure has been reported to decrease migraine attacks. Because many closures are carried out after an ischemic stroke, it is possible that migraine spontaneously improves after stroke.Methods: We have prospectively collected all patients with ischemic stroke and active migraine admitted to our stroke unit and have compared their migraine frequency before and 6, 12, and 24 months after stroke.Results: We studied 43 patients. Mean follow-up was 1.3 ± .5 years. The mean number of migraine attacks per month de...
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2013 Category: Neurology Authors: Bruno Censori, Tania Partziguian, Marco Poloni Tags: Original Articles Source Type: research
Differential Lesion Patterns on T2-weighted Magnetic Resonance Imaging and Fluid-attenuated Inversion Recovery Sequences in Cryptogenic Stroke Patients with Patent Foramen Ovale
Background: The present study aimed to determine lesion patterns and the stroke mechanisms in cryptogenic ischemic stroke patients with patent foramen ovale (PFO) on T2-weighted magnetic resonance imaging (T2WI) and fluid-attenuated inversion recovery (FLAIR) sequences combined.Methods: In this retrospective study, 38 patients with cryptogenic stroke and an isolated PFO compared with 51 cryptogenic stroke patients without PFO were evaluated and their characteristics of lesion patterns on T2WI and FLAIR sequences combined were investigated. The number, distribution of small ischemic lesions, and the frequency of multiple sm...
Source: Journal of Stroke and Cerebrovascular Diseases - April 15, 2014 Category: Neurology Authors: Yang-Yang Huang, Bei Shao, Xian-Da Ni, Jian-Ce Li Tags: Original Articles Source Type: research
Synthetic Cannabis and Acute Ischemic Stroke
We describe 2 cases that introduce a previously unreported association between synthetic cannabis use and ischemic stroke in young adults. A 22-year-old woman presented with dysarthria, left hemiplegia, and left hemianesthesia within hours of first use of synthetic cannabis. She was healthy and without identified stroke risk factors other than oral contraceptive use and a patent foramen ovale without venous thromboses. A 26-year-old woman presented with nonfluent aphasia, left facial droop, and left hemianesthesia approximately 12 hours after first use of synthetic cannabis. Her other stroke risk factors included migraine ...
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2013 Category: Neurology Authors: Miya E. Bernson-Leung, Lester Y. Leung, Sandeep Kumar Tags: Case Reports Source Type: research
Ischemic Stroke and Patent Foramen Ovale: Risk Factors and Genetic Profile
Conclusions: We found that F2, which previously has been described as being a possible link between PFO and ICVD, was significantly associated with ICVD and PFO. There was also a trend toward an association between 2 other polymorphisms in the APO-CIII gene and PFO and ICVD.
Source: Journal of Stroke and Cerebrovascular Diseases - July 12, 2012 Category: Neurology Authors: Maria Lantz, Christina Sjöstrand, Konstantinos Kostulas Tags: Original Articles Source Type: research
Patent Foramen Ovale and Infarct Volume in Cryptogenic Stroke
Background: The causal relationship between patent foramen ovale (PFO) and stroke is controversial. We hypothesized that if PFO is a pathway of embolic source, there might be a correlation between PFO characteristics (ie, size or extent of shunt) and ischemic lesion burden (ie, infarct volume and number).Methods: From ischemic stroke patients admitted to Asan Medical Center between January 2000 and October 2007, we identified those who had (1) acute ischemic lesion on diffusion-weighted imaging within 5 days of symptom onset and (2) cryptogenic stroke and only PFO detected by transesophageal echocardiography. PFO characte...
Source: Journal of Stroke and Cerebrovascular Diseases - June 7, 2013 Category: Neurology Authors: Jin-Man Jung, Jong-Young Lee, Hye-Jin Kim, Youngrok Do, Sun U. Kwon, Jong S. Kim, Jae-Kwan Song, Dong-Wha Kang Tags: Original Articles Source Type: research
Patent Foramen Ovale Closure in the Setting of Cryptogenic Stroke: A Meta-Analysis of Five Randomized Trials
The clinical benefit of patent foramen ovale (PFO) closure after cryptogenic stroke has been a topic of debate for decades. Recently, 3 randomized controlled trials of PFO closure in patients with cryptogenic stroke demonstrated a significantly reduced risk of recurrent stroke compared with standard medical therapy alone. This meta-analysis was performed to clarify the efficacy of PFO closure for future stroke prevention in this population.
Source: Journal of Stroke and Cerebrovascular Diseases - May 24, 2018 Category: Neurology Authors: Lohit Garg, Affan Haleem, Shweta Varade, Keithan Sivakumar, Mahek Shah, Brijesh Patel, Manyoo Agarwal, Sahil Agrawal, Megan Leary, Bryan Kluck Source Type: research
Cost-Effectiveness Analysis of Percutaneous Patent Foramen Ovale Closure Preventing Secondary Ischemic Stroke in Japan
Cryptogenic ischemic stroke is a type of ischemic stroke for which the mechanism of onset and etiology cannot be explained or specified by any known mechanisms/factors. The possible involvement of patent foramen ovale (PFO) in the etiology of cryptogenic ischemic stroke has been reported.1 It was previously reported that occult atrial fibrillation and PFO were embolic sources that caused cryptogenic ischemic stroke.2 PFO is an opening formed during the course of fetal atrial septum development. Usually, it closes spontaneously after birth; however, PFO remains patent after maturation to adulthood.
Source: Journal of Stroke and Cerebrovascular Diseases - June 18, 2021 Category: Neurology Authors: Sachie Inoue, Ataru Igarashi, Yasuyuki Iguchi, Teiji Akagi Source Type: research
Risk of Stroke in Patients with Patent Foramen Ovale: An Updated Meta-analysis of Observational Studies
Background: Although patent foramen ovale (PFO) is considered to be associated with cryptogenic stroke (CS), there remains an ongoing disputation on this issue because of unstable results from randomized controlled trials. The aim of this study was to reassess the PFO effect on stroke through observational data.Methods: An electronic search of PubMed, Web of Science, and China National Knowledge Infrastructure (CNKI) were finished. Only case–control studies and cohort studies in Chinese or English were included in the analysis. Then random-effected meta-analysis models were performed to assess the association between PFO...
Source: Journal of Stroke and Cerebrovascular Diseases - February 3, 2014 Category: Neurology Authors: Bing Ma, Guangcong Liu, Xin Chen, Jianming Zhang, Yiting Liu, Jingpu Shi Tags: Original Articles Source Type: research
The Fragility Index in Randomized Controlled Trials for Patent Foramen Ovale Closure in Cryptogenic Stroke
Background and Purpose: The routine use of percutaneous transcatheter patent foramen ovale closure (PPFOC) to prevent recurrent stroke in patients with cryptogenic stroke is still a matter of debate after completion major randomized controlled trials (RCTs). Methods: The fragility index of RCTs evaluating effect of PPFOC against medial therapy alone in stroke prevention was calculated to assess the robustness of statistically significant findings. Results: Literature search with PubMed identifies 6 RCTs on PPFOC.
Source: Journal of Stroke and Cerebrovascular Diseases - March 15, 2019 Category: Neurology Authors: Mehmet Akif Topcuoglu, Ethem Murat Arsava Source Type: research
Diagnostic and Therapeutic Value of Echocardiography during the Acute Phase of Ischemic Stroke
Conclusions: Echocardiography, as currently practiced in our stroke unit, allows detection of CSE in one patient in five, and leads to change in therapy in half of these cases. Our results suggest that TTE should be used for all patients admitted for IS, and to limit the use of TEE to younger patients.
Source: Journal of Stroke and Cerebrovascular Diseases - August 8, 2014 Category: Neurology Authors: Marie Gaudron, Isabelle Bonnaud, Aaurélia Ros, Frédéric Patat, Bertrand de Toffol, Bruno Giraudeau, Séverine Debiais Tags: Original Articles Source Type: research
Closure versus Medical Therapy for Patent Foramen Ovale in Patients with Cryptogenic Stroke: An Updated Meta-Analysis of Randomized Controlled Trials
Debate continues about whether percutaneous closure of patent foramen ovale (PFO) is a better strategy for the treatment of patients with cryptogenic stroke in comparison with medical therapy alone. We performed an updated meta-analysis of 6 randomized controlled trials (RCTs) to assess the effectiveness and safety of percutaneous closure of PFO as secondary prevention for patients with previous cryptogenic stroke compared to medical therapy.
Source: Journal of Stroke and Cerebrovascular Diseases - September 2, 2018 Category: Neurology Authors: Baoshan Qiu, Ying Cai, Dilong Wang, Jing Lin, Yuhua Fan Source Type: research
Residual Shunt after Patent Foramen Ovale Device Closure in Patients With Cryptogenic Stroke: Serial Bubble Contrast Transesophageal Echocardiography Data
Percutaneous closure of patent foramen ovale (PFO) is an alternative option to medical treatment for secondary prevention for cryptogenic stroke (CS). Despite technical success of procedure, residual shunt (RS) which is a presumable cause for recurrent stroke is observed in some patients. We evaluated the RS with serial follow-up bubble contrast transesophageal echocardiography (BCTEE) after PFO closure.
Source: Journal of Stroke and Cerebrovascular Diseases - November 3, 2018 Category: Neurology Authors: Jeonggeun Moon, Minsu Kim, Pyung Chun Oh, Dong Hoon Shin, Hyeon-MI Park, Youn Yi Jo, Ji Sung Lee, Woong Chol Kang Source Type: research
Comparison of Antiplatelet Therapies for Prevention of Patent Foramen Ovale-Associated Stroke
The REDUCE study demonstrated a reduction in the risk of recurrent stroke with patent foramen ovale closure and antiplatelet therapy compared to antiplatelet therapy alone. The clinicians were allowed to choose among aspirin, clopidogrel, or aspirin/dipyridamole with the expectation that all antiplatelet therapies would have similar efficacy in this population. We tested that presumption by comparing recurrent stroke rates among antiplatelet agents within the control arm of the trial.
Source: Journal of Stroke and Cerebrovascular Diseases - February 6, 2020 Category: Neurology Authors: Scott E. Kasner, Bryan Randall, Grethe Andersen, Helle K. Iversen, Risto Roine, Christina Sjostrand, John F. Rhodes, Lars S øndergaard, The Gore REDUCE Study Investigators Source Type: research
Patent Foramen Ovale Closure in hospitalized stroke patients in the United: Is there a racial disparity?
Racial disparity in stroke is well documented. Whether such disparity exists in the frequency of Patent Foramen Ovale (PFO) closure among patients with ischemic stroke (IS) is unclear.
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2020 Category: Neurology Authors: Alain Lekoubou Tags: Poster 09 Source Type: research
