• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Stroke in the Young: Etiologies and Risk Factors (P7.124)
CONCLUSIONS: Stroke in the young shares many of the same common modifiable risk factors as stroke in the elderly including hypertension, hyperlipidemia, diabetes, and tobacco abuse. Other unique disease processes also contribute to stroke in this age group, often less modifiable. Given the devastating morbidity and mortality of stroke in this age group, a larger public health effort for primary and secondary prevention of stroke in the young should be aggressively pursued.Disclosure: Dr. Govind has nothing to disclose. Dr. Ahad has nothing to disclose. Dr. Iftekhar has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Govind, P., Ahad, R., Iftekhar, A. Tags: Cerebrovascular Disease and Interventional Neurology: Stroke in Young Source Type: research

Body Mass Index and Stroke Subtype in a Young Adult Stroke Population (P7.126)
CONCLUSIONS: In our group of young adult stroke patients, we found the highest BMI in the group with intracranial atherosclerosis. Although this group represented a small number of patients, this young adult population is at increased risk for future strokes. It is important to educate them on lifestyle modifications such as weight loss and exercise in addition to the treatment of hypertension, diabetes mellitus and hyperlipidemia.Disclosure: Dr. Youn has nothing to disclose. Dr. Aung has nothing to disclose. Dr. Afrasiabi has nothing to disclose. Dr. Clark has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Youn, J., Aung, T., Afrasiabi, M., Clark, J. Tags: Cerebrovascular Disease and Interventional Neurology: Stroke in Young Source Type: research

An index to identify stroke-related vs incidental patent foramen ovale in cryptogenic stroke
Conclusion: Clinical characteristics identify CS patients who vary markedly in PFO prevalence, reflecting clinically important variation in the probability that a discovered PFO is likely to be stroke-related vs incidental. Patients in strata more likely to have stroke-related PFOs have lower recurrence risk.
Source: Neurology - August 12, 2013 Category: Neurology Authors: Kent, D. M., Ruthazer, R., Weimar, C., Mas, J.-L., Serena, J., Homma, S., Di Angelantonio, E., Di Tullio, M. R., Lutz, J. S., Elkind, M. S. V., Griffith, J., Jaigobin, C., Mattle, H. P., Michel, P., Mono, M.-L., Nedeltchev, K., Papetti, F., Thaler, D. E. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Risk factors in epidemiology ARTICLE Source Type: research

Paroxysmal Atrial Fibrillation Detection Rates In Cryptogenic Stroke Patients Selected By Stroke Specialists For Prolonged Cardiac Monitoring (P1.053)
CONCLUSION: Long term cardiac monitoring with ICM has a very high yield of detecting PAF in cryptogenic stroke patients when selected by a stroke expert.Disclosure: Dr. Salahuddin has nothing to disclose. Dr. Zaidi has nothing to disclose. Dr. Tietjen holds stock and/or stock options in Johnson & Johnson and Stryker. Dr. Cummings has nothing to disclose. Dr. Jumaa has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Salahuddin, H., Zaidi, S., Tietjen, G., Cummings, J., Jumaa, M. Tags: Cerebrovascular Disease and Interventional Neurology: Atrial Fibrillation and Cardio-embolic Stroke Source Type: research

Recurrent stroke predictors differ in medically treated patients with pathogenic vs other PFOs
Conclusion: Predictors of recurrence differ when PFO relatedness is classified by the RoPE score, suggesting that patients with CS and PFO form a heterogeneous group with different stroke mechanisms. Echocardiographic features were only associated with recurrence in the high RoPE score group.
Source: Neurology - July 14, 2014 Category: Neurology Authors: Thaler, D. E., Ruthazer, R., Weimar, C., Mas, J.-L., Serena, J., Di Angelantonio, E., Papetti, F., Homma, S., Mattle, H. P., Nedeltchev, K., Mono, M.-L., Jaigobin, C., Michel, P., Elkind, M. S. V., Di Tullio, M. R., Lutz, J. S., Griffith, J., Kent, D. M. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Risk factors in epidemiology ARTICLE Source Type: research

Routine troponin measurements are unnecessary in acute ischemic stroke evaluations (P4.285)
CONCLUSIONS: Troponin elevation in patients with ischemic stroke is not caused by acute myocardial ischemia unless iatrogenic in the setting of vasopressor administration. Serum troponins should be measured based on clinical context rather than routinely in all acute ischemic stroke patients.Disclosure: Dr. Ali has nothing to disclose. Dr. Young has nothing to disclose. Dr. Rabinstein has received royalty payments from Elsevier and Oxford University Press. Dr. Rabinstein has received research support from DJO Global. Dr. Flemming has nothing to disclose. Dr. Fugate has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Ali, F., Young, J., Rabinstein, A., Flemming, K., Fugate, J. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Ischemic Stroke Care Source Type: research

Potential new uses of non-vitamin K antagonist oral anticoagulants to treat and prevent stroke
Conclusion: There may be a role for NOACs in stroke prevention and treatment beyond atrial fibrillation. Randomized controlled trials are needed to compare NOACs to current stroke prevention and treatment strategies in certain subgroups of patients with cerebrovascular disease.
Source: Neurology - September 21, 2015 Category: Neurology Authors: Yaghi, S., Kamel, H., Elkind, M. S. V. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Infarction, Cerebral venous thrombosis VIEWS & amp;amp; REVIEWS Source Type: research

Prothrombotic States and Ischemic Stroke in the Young (P3.231)
Conclusions: There is no association between prothrombotic risk factors (analyzed individually or as a group) and idiopathic ischemic stroke in the young, even in those with a PFO or with migraine.Disclosure: Dr. Boudjani has nothing to disclose. Dr. Lanthier has received compensation for activities with Bristol-Myers-Squibb, Sanofi-Aventis, Boehringer-Ingelheim, and Astra-Zeneca as a speaker.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Boudjani, H., Lanthier, S. Tags: Stroke in the Young Source Type: research

Practice advisory: Recurrent stroke with patent foramen ovale (update of practice parameter): Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology
Conclusions: Percutaneous PFO closure with the STARFlex device possibly does not provide a benefit in preventing stroke vs medical therapy alone (risk difference [RD] 0.13%, 95% confidence interval [CI] –2.2% to 2.0%). Percutaneous PFO closure with the AMPLATZER PFO Occluder possibly decreases the risk of recurrent stroke (RD –1.68%, 95% CI –3.18% to –0.19%), possibly increases the risk of new-onset atrial fibrillation (AF) (RD 1.64%, 95% CI 0.07%–3.2%), and is highly likely to be associated with a procedural complication risk of 3.4% (95% CI 2.3%–5%). There is insufficient evidence to d...
Source: Neurology - August 21, 2016 Category: Neurology Authors: Messe, S. R., Gronseth, G., Kent, D. M., Kizer, J. R., Homma, S., Rosterman, L., Kasner, S. E. Tags: All Cerebrovascular disease/Stroke SPECIAL ARTICLE Source Type: research

Incidence of atrial fibrillation detected by implantable loop recorders in unexplained stroke
Conclusion: In patients with unexplained stroke, AF was detected by ILR in 25.5%. Predictors of AF were identified, which may help to target investigations. ILRs may have a central role in the future in the investigation of patients with unexplained stroke.
Source: Neurology - April 22, 2013 Category: Neurology Authors: Cotter, P. E., Martin, P. J., Ring, L., Warburton, E. A., Belham, M., Pugh, P. J. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Cardiac; see Cerebrovascular Disease/Cardiac ARTICLE Source Type: research

Toward a better understanding of PFO and stroke risk
A patent foramen ovale (PFO) is a remnant of the fetal circulation and may be found in approximately 25% of adults.1 Multiple case-control studies have demonstrated an association between PFO and cryptogenic ischemic stroke, particularly in younger patients.2 The mechanism for the association is presumed to be venous thromboembolism through the PFO and into the cerebral circulation (i.e., paradoxical embolization).3 Randomized studies of percutaneous PFO closure devices for secondary stroke prevention have been in progress for years with slow enrollment because of off-label use of atrial septal defect closure devices.4,5 T...
Source: Neurology - August 12, 2013 Category: Neurology Authors: Messe, S. R., Kernan, W. N. Tags: Stroke in young adults, Stroke prevention, Prognosis, Embolism EDITORIALS Source Type: research

Determinants of antithrombotic choice for patent foramen ovale in cryptogenic stroke
Conclusion: Both antithrombotic regimens are widely used for secondary stroke prevention in patients with CS and PFO. Radiologic and echocardiographic features were strongly associated with treatment choice, whereas conventional vascular risk factors were not. Prior observational studies are likely to be biased by confounding by indication.
Source: Neurology - November 17, 2014 Category: Neurology Authors: Thaler, D. E., Ruthazer, R., Weimar, C., Serena, J., Mattle, H. P., Nedeltchev, K., Mono, M.-L., Di Angelantonio, E., Elkind, M. S. V., Di Tullio, M. R., Homma, S., Michel, P., Meier, B., Furlan, A. J., Lutz, J. S., Kent, D. M. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Risk factors in epidemiology ARTICLE Source Type: research

Migraine makes the stroke grow faster?
Long associated with increased incidence of stroke,1,2 migraine has been linked with mechanisms involving the vasculature (vasospasm, arterial dissection, endothelial dysfunction, venous thrombosis), heart (patent foramen ovale), and blood (hypercoagulability).3 Since cerebral ischemia can induce cortical spreading depression, the physiologic process underlying aura, migraine with aura may theoretically represent a TIA equivalent in a subset of people. In addition to the heightened occurrence of stroke in migraineurs, a growing body of evidence suggests more dire consequences when stroke occurs, with experiments in mice wi...
Source: Neurology - November 30, 2015 Category: Neurology Authors: Tietjen, G. E., Sacco, S. Tags: Migraine, All Cerebrovascular disease/Stroke EDITORIALS Source Type: research

Predictors for atrial fibrillation detection after cryptogenic stroke: Results from CRYSTAL AF
Conclusion: Increasing age and a prolonged PR interval at enrollment were independently associated with an increased AF incidence in CS patients. However, they offered only moderate predictive ability in determining which CS patients had AF detected by the ICM.
Source: Neurology - January 18, 2016 Category: Neurology Authors: Thijs, V. N., Brachmann, J., Morillo, C. A., Passman, R. S., Sanna, T., Bernstein, R. A., Diener, H.-C., Di Lazzaro, V., Rymer, M. M., Hogge, L., Rogers, T. B., Ziegler, P. D., Assar, M. D. Tags: Stroke prevention, Prognosis, All Cerebrovascular disease/Stroke, Clinical trials Randomized controlled (CONSORT agreement), Risk factors in epidemiology ARTICLE Source Type: research

Ischemic stroke after pellet embolization
A 9-year-old boy was shot with a pellet shotgun and developed a visual field deficit. Head CT revealed a pellet in the left ambien cistern, in the left posterior cerebral artery on catheter angiography (figure). Chest fluoroscopy revealed multiple thoracic pellets, including a mobile cardiac pellet (video on the Neurology® Web site at Neurology.org). There was no clear cardiac injury, patent foramen ovale, or skull penetration. Arterial embolization of a pellet from the chest to the intracranial vasculature likely caused a stroke.1,2 We considered arteriotomy, endovascular retrieval, and medical therapy. The establishe...
Source: Neurology - June 8, 2015 Category: Neurology Authors: Aghaebrahim, A., Giurgiutiu, D.-V., Jankowitz, B. T., Jovin, T., Jadhav, A. P. Tags: All Cerebrovascular disease/Stroke, Embolism VIDEO NEUROIMAGES Source Type: research

Pages: 1  2  3