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A brief report on incidence, radiographic feature and prognostic significance of brain MRI changes after anti-PD-1/PD-L1 therapy in advanced non-small cell lung cancer
ConclusionsBrain MRI aberrations developed after ICI treatment are not uncommon, and their manifestations vary a lot. Patients developing brain MRI aberrations tended to have better prognosis, which needed to be further investigated.
Source: Cancer Immunology, Immunotherapy - October 6, 2021 Category: Cancer & Oncology Source Type: research

Recurrent Stroke in Giant Cell Arteritis Despite Immunotherapy
Conclusions: This case highlights several important features of strokes in GCA: the predilection for the dural entry point of cerebral blood vessels, the progression of disease despite steroids, and the need to quickly escalate treatment in these cases. As seen in our patient, however, this disease carries high morbidity and mortality and patients often have poor outcomes despite aggressive immunosuppression.
Source: The Neurologist - June 28, 2019 Category: Neurology Tags: Case Report/Case Series Source Type: research

Vasculitic neuropathy following exposure to minocycline
Conclusions: Our findings suggest that the typical neuropathy associated with minocycline use is painful single or multiple mononeuropathy due to peripheral nerve vasculitis, which may also be accompanied by presumed CNS vasculitis (presenting as stroke).
Source: Neurology Neuroimmunology and Neuroinflammation - November 12, 2015 Category: Neurology Authors: Baratta, J. M., Dyck, P. J. B., Brand, P., Thaisetthawatkul, P., Dyck, P. J., Engelstad, J. K., Goodman, B., Karam, C. Tags: All Cerebrovascular disease/Stroke, Other cerebrovascular disease/ Stroke, All Immunology, Autoimmune diseases, Vasculitis Article Source Type: research