• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

A Novel Triple-Cell Two-Dimensional Model to Study Immune-Vascular Interplay in Atherosclerosis
Conclusions We have developed a co-culture model for the study of the immune-vascular interplay in atherosclerosis consisting of ECs, SMCs and an inflammatory compartment. In order to validate this model, we have demonstrated that the triple-cell 2D culture of ECs, SMCs, and THP-1 macrophage-like cells significantly alters the phenotype of ECs and SMCs within this culture in comparison with EC/SMC, EC/THP-1, or SMC/THP-1 double-cell cultures. Our results are indicative of the multi-directional communication between highly plastic vascular stromal cells and the immune system, which is now well recognized in the field, and ...
Source: Frontiers in Immunology - April 23, 2019 Category: Allergy & Immunology Source Type: research

Stroke and syphilis: A retrospective study of 53 patients.
CONCLUSION: A diagnosis of syphilitic stroke should be suspected in young patients as a manifestation of syphilis, and tests for neurosyphilis should be routine in neurology departments to make a prompt diagnosis, thereby preventing psychological sequelae. PMID: 29631855 [PubMed - as supplied by publisher]
Source: Revue Neurologique - April 12, 2018 Category: Neurology Tags: Rev Neurol (Paris) Source Type: research

Meningovascular Neurosyphilis Presenting as Ischemic Stroke in an HIV Positive Patient (P2.297)
CONCLUSIONS: MVNS should be considered in AIS patients without known risk factors, especially in patients who are HIV positive. Prompt treatment can halt progression of and possibly improve symptomatology. Diagnosis and improvement can be monitored with intracranial arterial wall imaging using contrast-enhanced MRI.Disclosure: Dr. Tipirneni has nothing to disclose. Dr. Gordon-Perue has nothing to disclose. Dr. DeSousa has nothing to disclose. Dr. Koch has nothing to disclose. Dr. Romano has received personal compensation for activities with NovaVision. Dr. Malik has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Tipirneni, A., Gordon-Perue, G., DeSousa, K., Koch, S., Romano, J., Malik, A. Tags: Cerebrovascular Disease and Interventional Neurology: Inflammation and Immunology Source Type: research