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Noninvasive spinal neuromodulation to map and augment lower urinary tract function in rhesus macaques.
Abstract Dysfunction of the lower urinary tract (LUT) is prevalent in neurological disorders, including multiple sclerosis, stroke, spinal cord injury and neurodegenerative conditions. Common symptoms include urgency, incontinence, and urinary retention. Recent advances in neuromodulation have resulted in improved treatments for overactive bladder symptoms of urgency, frequency, and nocturia. However, there are presently no treatments available for the induction of voiding to overcome urinary retention. We demonstrate that transcutaneous spinal cord stimulation (TSCS), a non-invasive intervention, applied over the...
Source: Experimental Neurology - August 6, 2019 Category: Neurology Authors: Havton LA, Christe KL, Edgerton VR, Gad PN Tags: Exp Neurol Source Type: research