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Tetracycline-, Doxycycline-, Minocycline-Induced Pseudotumor Cerebri and Esophageal Perforation
AbstractTetracyclines are a class of broad-spectrum bacteriostatic antibiotics used to treat many infections, including methicillin-resistantStaphylococcus aureus (MRSA), acne, pelvic inflammatory disease, chlamydial infections, and a host of zoonotic infections. These drugs work by inhibiting protein synthesis in bacterial ribosomes, specifically by disallowing aminoacyl-tRNA molecules from binding to the ribosomal acceptor sites. While rare, tetracycline antibiotics, particularly minocycline and doxycycline, are associated with an increased risk of developing esophageal perforation and pseudotumor cerebri (PTC, or idiopa...
Source: Advances in Therapy - February 10, 2023 Category: Drugs & Pharmacology Source Type: research

Decompressive craniectomy index: Does the size of decompressive craniectomy matter in malignant middle cerebral artery infarction?
CONCLUSION: In our series, the relation between bone flap size and theoretical maximum supratentorial hemicranium area (DCI) in patients with malignant MCA infarction was associated with prognosis. Further studies are necessary to confirm these findings.PMID:36600778 | PMC:PMC9805638 | DOI:10.25259/SNI_895_2022
Source: Surgical Neurology International - January 5, 2023 Category: Neurosurgery Authors: Thiago Pereira Rodrigues Mariana Athaniel Silva Rodrigues Leonardo Favi Bocca Feres Eduardo Chaddad-Neto Sergio Cavalheiro Edson Amaro Junior Gisele Sampaio Silva Italo Capraro Suriano Ricardo Silva Centeno Source Type: research

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