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Specialty: Drugs & Pharmacology
Condition: Subarachnoid Hemorrhage
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Total 112 results found since Jan 2013.
Subfatin, asprosin, alamandine and maresin-1 in cerebral ischemia, intracranial and subarachnoid hemorrhages
CONCLUSIONS: Decreased MaR-1, SUB, ALA and increased ASP compared to the control values may play a role in the physiopathology of these diseases. MaR-1, SUB, ALA, and ASP differences between SAH, CI and ICH patients may also guide clinicians along with SBP, DBP and glucose values.PMID:37259728 | DOI:10.26355/eurrev_202305_32453
Source: European Review for Medical and Pharmacological Sciences - June 1, 2023 Category: Drugs & Pharmacology Authors: S Albayrak M A Aydin K Ugur O Hanbeyoglu S Aydin E Erol A Kilinc V Acar I Sahin S Aydin Source Type: research
Cytochrome P450-derived eicosanoids in brain: From basic discovery to clinical translation
Adv Pharmacol. 2023;97:283-326. doi: 10.1016/bs.apha.2022.11.002. Epub 2023 Jan 11.ABSTRACTCytochrome P450 metabolism of arachidonic acid produces epoxyeicosatrienoates (EETs) and hydroxyeicosatetraenoates (HETEs). Both classes of eicosanoids play important and opposing roles in brain function and disease. EETs promote vasodilation and exhibit antiinflammatory and cytoprotective properties; their biological action is blunted by metabolism to less active diols by the enzyme soluble epoxide hydrolase (sEH). EETs levels are dysregulated in disease states, primarily due to increased activity of sEH. Inhibition of sEH is a prom...
Source: Advances in Pharmacology - May 26, 2023 Category: Drugs & Pharmacology Authors: Catherine M Davis Aseel H Ibrahim Nabil J Alkayed Source Type: research
