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Periprocedural cerebrovascular complications and 30-day outcomes of endovascular treatment for intracranial vertebral artery dissecting aneurysms
CONCLUSIONS: Hyperlipidemia, IS history, and SAH were independent predictors for overall periprocedural cerebrovascular complications of endovascular treatment for IVADAs, but aneurysmal height was an independent protective factor. SAH and preprocedural mRS score > 2 were independent risk factors for perforator occlusion stroke. Preprocedural mRS score > 2 and periprocedural complications were independent risk factors for 30-day unfavorable clinical outcomes.PMID:36401540 | DOI:10.3171/2022.10.JNS221953
Source: Journal of Neurosurgery - November 19, 2022 Category: Neurosurgery Authors: Jiangli Han Fei Liu Jigang Chen Xin Tong Mingyang Han Fei Peng Hao Niu Lang Liu Aihua Liu Source Type: research

Activation of the NLRP3/IL-1 β/MMP-9 pathway and intracranial aneurysm rupture associated with the depletion of ERα and Sirt1 in oophorectomized rats
CONCLUSIONS: To the authors' knowledge, this work represents the first demonstration that, in an aneurysm model under estrogen-deficient conditions, the depletion of ERα and Sirt1 may contribute to activation of the NLRP3/IL-1β/MMP-9 pathway, facilitating the rupture of IAs in the estrogen-deficient rat IA rupture model.PMID:35594890 | DOI:10.3171/2022.4.JNS212945
Source: Journal of Neurosurgery - May 20, 2022 Category: Neurosurgery Authors: Tadashi Yamaguchi Takeshi Miyamoto Eiji Shikata Izumi Yamaguchi Kenji Shimada Kenji Yagi Yoshiteru Tada Masaaki Korai Keiko T Kitazato Yasuhisa Kanematsu Yasushi Takagi Source Type: research

An altered posterior question-mark incision is associated with a reduced infection rate of cranioplasty after decompressive hemicraniectomy.
CONCLUSIONS: The primary goal of this retrospective cohort analysis was to identify adjustable risk factors to prevent post-CP complications. In this analysis, a posterior question-mark incision proved beneficial regarding infection and CP failure. The authors believe that these findings are caused by the better vascularized skin flap due to preservation of the superficial temporal artery and partial preservation of the occipital artery. In this trial, the posterior question-mark incision was identified as an easily and costless adaptable technique to reduce CP failure rates. PMID: 32330877 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - April 23, 2020 Category: Neurosurgery Authors: Veldeman M, Daleiden L, Hamou H, Höllig A, Clusmann H Tags: J Neurosurg Source Type: research

Effects of case volume and comprehensive stroke center capabilities on patient outcomes of clipping and coiling for subarachnoid hemorrhage.
CONCLUSIONS: The effects of case volume and CSC capabilities on in-hospital mortality and short-term functional outcomes in SAH patients differed between patients undergoing clipping and those undergoing coiling. In the modern endovascular era, better outcomes of clipping may be achieved in facilities with high CSC capabilities. PMID: 32168489 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - March 12, 2020 Category: Neurosurgery Authors: Kurogi R, Kada A, Ogasawara K, Kitazono T, Sakai N, Hashimoto Y, Shiokawa Y, Miyachi S, Matsumaru Y, Iwama T, Tominaga T, Onozuka D, Nishimura A, Arimura K, Kurogi A, Ren N, Hagihara A, Nakaoku Y, Arai H, Miyamoto S, Nishimura K, Iihara K Tags: J Neurosurg Source Type: research

Soluble receptor for advanced glycation end products as a biomarker of symptomatic vasospasm in subarachnoid hemorrhage.
CONCLUSIONS: Plasma sRAGE levels can be used as a potential biomarker for predicting SVS after SAH. PMID: 31675694 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - October 31, 2019 Category: Neurosurgery Authors: Aida Y, Kamide T, Ishii H, Kitao Y, Uchiyama N, Nakada M, Hori O Tags: J Neurosurg Source Type: research

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