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Source: Stroke
Condition: Subarachnoid Hemorrhage
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Total 216 results found since Jan 2013.
High Serum Level of Matrix Metalloproteinase-7 Is Associated With Increased Risk of Spontaneous Subarachnoid Hemorrhage Clinical Sciences
Conclusions—High serum level of MMP-7 was associated with increased risk of incident spontaneous SAH, independently of the main risk factors for SAH. High serum levels of MMP-2 and MMP-9 did not predict SAH risk.
Source: Stroke - June 25, 2018 Category: Neurology Authors: Martin Soderholm, Gunilla Nordin Fredrikson, Jan Nilsson, Gunnar Engstrom Tags: Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage Original Contributions Source Type: research
Baroreflex Impairment After Subarachnoid Hemorrhage Is Associated With Unfavorable Outcome Clinical Sciences
Conclusions—In SAH, early BRS was associated with 3-month outcome. This conclusion requires confirmation on a larger number of patients in a multicentre study.
Source: Stroke - June 25, 2018 Category: Neurology Authors: Nathalie Nasr, Rita Gaio, Marek Czosnyka, Karol Budohoski, Xiuyun Liu, Joseph Donnelly, Marek Sykora, Peter Kirkpatrick, Anne Pavy-Le Traon, Christina Haubrich, Vincent Larrue, Peter Smielewski Tags: Autonomic Nervous System, Pathophysiology, Cerebrovascular Disease/Stroke Original Contributions Source Type: research
Neurologic Outcome Predictors in Pediatric Intracerebral Hemorrhage Brief Report
Background and Purpose—Intracerebral hemorrhage is a considerable source of morbidity and mortality. This 3-center study describes outcomes of pediatric intracerebral hemorrhage and identifies 2-year neurological outcome predictors.Methods—Children 29 days to 18 years of age presenting with intracerebral hemorrhage from March 2007 to May 2015 were enrolled prospectively. Exclusion criteria included trauma; intracranial tumor; hemorrhagic transformation of arterial ischemic stroke or cerebral sinovenous thrombosis; isolated subdural, epidural, or subarachnoid hemorrhage; and abnormal baseline neurological function. Intr...
Source: Stroke - June 25, 2018 Category: Neurology Authors: Giulia S. Porcari, Lauren A. Beslow, Rebecca N. Ichord, Daniel J. Licht, Jonathan T. Kleinman, Lori C. Jordan Tags: Pediatrics, Prognosis, Mortality/Survival, Intracranial Hemorrhage Brief Reports Source Type: research
Relation of RhoA in Peripheral Blood Mononuclear Cells With Severity of Aneurysmal Subarachnoid Hemorrhage and Vasospasm Brief Report
Conclusions—Our preliminary results indicate that RhoA expression and activity in peripheral blood mononuclear cells might be related with aSAH severity and cerebral vasospasm. RhoA is a potential biomarker of the risks associated with aSAH.
Source: Stroke - May 25, 2018 Category: Neurology Authors: Maria del Carmen Gonzalez–Montelongo, Juan Jose Egea–Guerrero, Francisco Murillo–Cabezas, Rafaela Gonzalez–Montelongo, Zaida Ruiz de Azua–Lopez, Ana Rodriguez–Rodriguez, Angel Vilches–Arenas, Antonio Castellano, J Tags: Basic Science Research, Biomarkers Brief Reports Source Type: research
Long-Term Risk of Hemorrhagic Stroke in Young Patients With Congenital Heart Disease Clinical Sciences
Conclusions—The relative risk of hemorrhagic stroke among children and young adults with CHD was almost 8× higher than that of matched controls from the general population, although the absolute risk was low. The highest risk of ICH and SAH occurred in patients with severe nonconotruncal defects and coarctation of the aorta.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Kok Wai Giang, Zacharias Mandalenakis, Mikael Dellborg, Georgios Lappas, Peter Eriksson, Per-Olof Hansson, Annika Rosengren Tags: Epidemiology, Cerebrovascular Disease/Stroke, Cerebrovascular Malformations, Intracranial Hemorrhage Original Contributions Source Type: research
Risk Factors for and Clinical Consequences of Multiple Intracranial Aneurysms Clinical Sciences
Conclusions—Female sex, higher age, arterial hypertension, smoking, and familial IA are major risk factors for MIA. In addition, MIA patients are at risk for enhanced IA formation. Further studies are needed to evaluate rupture risk and the role of ethnicity, especially in the context of increased MIA identification with improved neurovascular imaging.
Source: Stroke - March 26, 2018 Category: Neurology Authors: Ramazan Jabbarli, Thiemo Florin Dinger, Marvin Darkwah Oppong, Daniela Pierscianek, Philipp Dammann, Karsten H. Wrede, Klaus Kaier, Martin Kohrmann, Michael Forsting, Christoph Kleinschnitz, Ulrich Sure Tags: Risk Factors, Cerebral Aneurysm, Cerebrovascular Disease/Stroke, Aneurysm Original Contributions Source Type: research
Microvasospasms After Experimental Subarachnoid Hemorrhage Do Not Depend on Endothelin A Receptors Basic Sciences
Conclusions—Our results indicate that ETA receptors, which mediate large artery spasms after SAH, do not seem to play a role in the development of microarterial spasms, suggesting that posthemorrhagic spasms are mediated by distinct mechanisms in large and small cerebral vessels. Given that cerebral microvessel dysfunction is a key factor for outcome after SAH, further research into the mechanisms that underlie posthemorrhagic microvasospasms is urgently needed.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Hanhan Liu, Ari Dienel, Karsten Scholler, Susanne M. Schwarzmaier, Kathrin Nehrkorn, Nikolaus Plesnila, Nicole A. Terpolilli Tags: Basic Science Research, Mechanisms, Pathophysiology, Translational Studies, Cerebrovascular Disease/Stroke Original Contributions Source Type: research
Size of Ruptured Intracranial Aneurysms Is Decreasing Brief Report
Background and Purpose—Decrease in the incidence of subarachnoid hemorrhage over the past decades has been related to decreased smoking rates, especially among
Source: Stroke - February 26, 2018 Category: Neurology Authors: Miikka Korja, Riku Kivisaari, Behnam Rezai Jahromi, Hanna Lehto Tags: Epidemiology, Cerebral Aneurysm, Cerebrovascular Disease/Stroke Brief Reports Source Type: research
Correction to: Predictors of In-Hospital Death After Aneurysmal Subarachnoid Hemorrhage: Analysis of a Nationwide Database (Swiss SOS Swiss Study on Aneurysmal Subarachnoid Hemorrhage) Correction
Source: Stroke - February 26, 2018 Category: Neurology Tags: Corrections Source Type: research
Stroke Incidence and Outcomes in Northeastern Greece Clinical Sciences
Conclusions—This is the largest to date population-based study in Greece documenting one of the highest stroke incidences ever reported in South Europe, highlighting the need for efficient stroke prevention and treatment strategies in Northeastern Greece.
Source: Stroke - January 22, 2018 Category: Neurology Authors: Georgios Tsivgoulis, Athanasia Patousi, Maria Pikilidou, Theodosis Birbilis, Aristeidis H. Katsanos, Michalis Mantatzis, Aristeidis Asimis, Nikolaos Papanas, Panagiotis Skendros, Aikaterini Terzoudi, Aikaterini Karamanli, Ioannis Kouroumichakis, Pantelis Tags: Epidemiology, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research
Predictors of In-Hospital Death After Aneurysmal Subarachnoid Hemorrhage Clinical Sciences
Background and Purpose—To identify predictors of in-hospital mortality in patients with aneurysmal subarachnoid hemorrhage and to estimate their impact.Methods—Retrospective analysis of prospective data from a nationwide multicenter registry on all aneurysmal subarachnoid hemorrhage cases admitted to a tertiary neurosurgical department in Switzerland (Swiss SOS [Swiss Study on Aneurysmal Subarachnoid Hemorrhage]; 2009–2015). Both clinical and radiological independent predictors of in-hospital mortality were identified, and their effect size was determined by calculating adjusted odds ratios (aORs) using multivariate ...
Source: Stroke - January 22, 2018 Category: Neurology Authors: Martin Nikolaus Stienen, Menno Germans, Jan–Karl Burkhardt, Marian C. Neidert, Christian Fung, David Bervini, Daniel Zumofen, Michel Rothlisberger, Serge Marbacher, Rodolfo Maduri, Thomas Robert, Martin A. Seule, Philippe Biȷlenga, Karl Schal Tags: Mortality/Survival, Cerebral Aneurysm, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage Original Contributions Source Type: research
Stroke Incidence by Major Pathological Type and Ischemic Subtypes in the Auckland Regional Community Stroke Studies Clinical Sciences
Conclusions—A lack of change in IS and ICH incidence may reflect a trend toward increased incidence of younger strokes. Increased rates of large-artery atherosclerosis and small-vessel occlusion are associated with increased smoking and high blood pressure. Ethnic differences in the proportional distribution of pathological stroke subtypes suggest differential exposure and susceptibility to risk factors.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Rita V. Krishnamurthi, Suzanne Barker-Collo, Varsha Parag, Priyakumari Parmar, Emma Witt, Amy Jones, Susan Mahon, Craig S. Anderson, P. Alan Barber, Valery L. Feigin Tags: Epidemiology, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research
Antihyperglycemic Agents Are Inversely Associated With Intracranial Aneurysm Rupture Clinical Sciences
Conclusions—Antihyperglycemic agent use rather than hyperglycemia is associated with decreased risk of aneurysmal subarachnoid hemorrhage, suggesting a possible protective effect of glucose-lowering agents in the pathogenesis of aneurysm rupture.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Anil Can, Victor M. Castro, Sheng Yu, Dmitriy Dligach, Sean Finan, Vivian S. Gainer, Nancy A. Shadick, Guergana Savova, Shawn Murphy, Tianxi Cai, Scott T. Weiss, Rose Du Tags: Risk Factors, Cerebral Aneurysm Original Contributions Source Type: research
Induced Hypertension for Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage Clinical Sciences
Conclusions—Before this trial, the effectiveness of induced hypertension for DCI in aneurysmal subarachnoid hemorrhage patients was unknown because current literature consists only of uncontrolled case series. The results from our premature halted trial do not add any evidence to support induced hypertension and show that this treatment can lead to serious adverse events.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT01613235.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Celine S. Gathier, Walter M. van den Bergh, Mathieu van der Jagt, Bon H. Verweiȷ, Jan Willem Dankbaar, Marcella C. Muller, Annemarie W. Oldenbeuving, Gabriel J.E. Rinkel, Arȷen J.C. Slooter, for the HIMALAIA Study Group* Tags: Treatment, Quality and Outcomes, Cerebrovascular Disease/Stroke Original Contributions Source Type: research
Transoceanic Management and Treatment of Aneurysmal Subarachnoid Hemorrhage Clinical Sciences
Conclusions—Our treatment strategy for aneurysmal subarachnoid hemorrhage resulted in a 30-day case fatality rate similar to those observed elsewhere, despite an 8-hour flight and a median treatment delay of 32 hours. This strategy therefore seems to be safe and reliable for isolated regions with small populations.
Source: Stroke - December 22, 2017 Category: Neurology Authors: Mehdi Mejdoubi, Mathieu Schertz, Sylvia Zanolla, Hossein Mehdaoui, Michel Piotin Tags: Cerebral Aneurysm, Intracranial Hemorrhage Original Contributions Source Type: research
