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Effect of apparent temperature on hospitalization from a spectrum of cardiovascular diseases in rural residents in Fujian, China
Environ Pollut. 2022 Mar 3:119101. doi: 10.1016/j.envpol.2022.119101. Online ahead of print.ABSTRACTCardiovascular disease (CVD) is a leading threat to global public health. Although associations between temperature and CVD hospitalization have been suggested for developed countries, limited evidence is available for developing countries or rural residents. Moreover, the effect of apparent temperature (AT) on the spectrum of cause-specific CVDs remains unknown. Based on 2,024,147 CVD hospitalizations for rural residents from eight regions in Fujian Province, China, during 2010-2016, a quasi-Poisson regression with distribu...
Source: Environmental Pollution - March 6, 2022 Category: Environmental Health Authors: Zhi-Ying Zhan Xue Zhong Jun Yang Zan Ding Xiao-Xu Xie Zhen-Quan Zheng Zhi-Jian Hu Source Type: research

Efficacies of minimally invasive puncture and small bone window craniotomy for hypertensive intracerebral hemorrhage, evaluation of motor-evoked potentials and comparison of postoperative rehemorrhage between the two methods.
Authors: Luan L, Li M, Sui H, Li G, Pan W Abstract Application value of the minimally invasive puncture and small bone window craniotomy in hypertensive intracerebral hemorrhage was investigated to explore the effects of the above treatment methods on motor-evoked potentials (MEPs) and postoperative rehemorrhage. Patients with hypertensive intracerebral hemorrhage who were admitted to Chengyang People's Hospital from March 2016 to December 2017 were selected and randomly divided into the minimally invasive group (n=40) and the craniotomy group (n=40). The minimally invasive group was treated with minimally invasive...
Source: Experimental and Therapeutic Medicine - January 28, 2019 Category: General Medicine Tags: Exp Ther Med Source Type: research

6-Bromoindirubin-3 ′-Oxime (6BIO) Suppresses the mTOR Pathway, Promotes Autophagy, and Exerts Anti-aging Effects in Rodent Liver
In this study, we aimed to investigate the anti-aging effect, and molecular mechanism, of the novel anti-aging drug 6BIO on naturally aged mouse liver. Rapamycin, a well-known promising anti-aging drug that delays aging through mTOR-dependent autophagy (Zhou and Ye, 2018), was used as the positive control in the study. To our knowledge, this is the first study to demonstrate the effects of 6BIO treatment in models of natural aging. Our results indicated that 6BIO ameliorates the decline of liver function with age, including lipid metabolism disorder, and attenuates hepatocyte senescence in aged mice, as revealed by altera...
Source: Frontiers in Pharmacology - April 9, 2019 Category: Drugs & Pharmacology Source Type: research

Jidong Restless Legs Syndrome Cohort Study: Objectives, Design, and Baseline Screening
This study will contribute to the scientific evidence on the association between RLS and cardiovascular risks and also provide an unprecedented opportunity for early detection and prevention of CVD.
Source: Frontiers in Neurology - October 13, 2021 Category: Neurology Source Type: research

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