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Condition: Ischemic Stroke
Drug: Proton Pump Inhibitors PPIs
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Total 156 results found since Jan 2013.
CYP2C19 Loss-of-Function Variants Associated with Long-term Ischemic Stroke Events During Clopidogrel Treatment in the Chinese Population
This study aims to determine whether CYP2C19 loss-of-function (LoF) variants were associated with long-term ischemic stroke risk in Chinese primary care patients treated with clopidogrel. Patients treated with clopidogrel were ascertained from a Chinese Electronic Medical Record linked with biobank for a retrospective cohort study. Their medical information was examined for the period from January 2018 to December 2021. Two CYP2C19 major loss of function variants (*2:rs4244285, *3: rs4986893) were genotyped. The clinical outcome was ischemic stroke event. Cox regression analysis was used to evaluate the association between...
Source: Clinical Pharmacology and Therapeutics - August 22, 2023 Category: Drugs & Pharmacology Authors: Peng Wu Ziqing Liu Zijian Tian Benrui Wu Jian Shao Qian Li Zhaoxu Geng Ying Pan Ke Lu Qiang Wang Tao Xu Kaixin Zhou Source Type: research
Antidepressants and the Risk of Ischemic Stroke in Older Adults According to the Degree of Serotonin Reuptake Inhibition: A Retrospective Cohort Study
CONCLUSION: The use of strong and intermediate SRIs should be considered carefully in older adult patients, especially when high-dose antidepressants are prescribed even for a short duration.PMID:37562992 | DOI:10.1016/j.jagp.2023.07.013
Source: The American Journal of Geriatric Psychiatry - August 10, 2023 Category: Psychiatry Authors: Kyoung-Eun Kwon Bo Ram Yang Mi-Sook Kim Byung-Joo Park Joongyub Lee Sun-Young Jung Source Type: research
Does proton pump inhibitor reduce the antiaggregant efficacy of aspirin in ischemic stroke?
Acta Neurol Taiwan. 2023 Mar 30;32(1):9-15.NO ABSTRACTPMID:36474449
Source: Acta Neurologica Taiwanica - December 7, 2022 Category: Neurology Authors: Tu ğba Özel Ali Ünal Sebahat Özdem Babur Dora Source Type: research
