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Artificial intelligence-based preventive, personalized and precision medicine for cardiovascular disease/stroke risk assessment in rheumatoid arthritis patients: a narrative review
Rheumatol Int. 2023 Aug 30. doi: 10.1007/s00296-023-05415-1. Online ahead of print.ABSTRACTThe challenges associated with diagnosing and treating cardiovascular disease (CVD)/Stroke in Rheumatoid arthritis (RA) arise from the delayed onset of symptoms. Existing clinical risk scores are inadequate in predicting cardiac events, and conventional risk factors alone do not accurately classify many individuals at risk. Several CVD biomarkers consider the multiple pathways involved in the development of atherosclerosis, which is the primary cause of CVD/Stroke in RA. To enhance the accuracy of CVD/Stroke risk assessment in the RA...
Source: Atherosclerosis - August 30, 2023 Category: Cardiology Authors: Mustafa Al-Maini Mahesh Maindarkar George D Kitas Narendra N Khanna Durga Prasanna Misra Amer M Johri Laura Mantella Vikas Agarwal Aman Sharma Inder M Singh George Tsoulfas John R Laird Gavino Faa Jagjit Teji Monika Turk Klaudija Viskovic Zoltan Ruzsa Sop Source Type: research

Development and validation of a nomogram for predicting stroke risk in rheumatoid arthritis patients
In conclusion, the nomogram can be used for individualized preoperative prediction of stroke risk in RA patients.PMID:34081620 | DOI:10.18632/aging.203071
Source: Aging - June 3, 2021 Category: Biomedical Science Authors: Fangran Xin Lingyu Fu Bowen Yang Haina Liu Tingting Wei Cunlu Zou Bingqing Bai Source Type: research

Hacking The Nervous System
(Photo: © Job Boot) One nerve connects your vital organs, sensing and shaping your health. If we learn to control it, the future of medicine will be electric.When Maria Vrind, a former gymnast from Volendam in the Netherlands, found that the only way she could put her socks on in the morning was to lie on her back with her feet in the air, she had to accept that things had reached a crisis point. “I had become so stiff I couldn’t stand up,” she says. “It was a great shock because I’m such an active person.”It was 1993. Vrind was in her late 40s and working two jobs, athletics coach and a carer for disabled ...
Source: Science - The Huffington Post - May 30, 2015 Category: Science Source Type: news

Vascular adhesion protein-1 (VAP-1) in vascular inflammatory diseases
Vasa. 2022 Oct 6. doi: 10.1024/0301-1526/a001031. Online ahead of print.ABSTRACT Vascular adhesion protein-1 (VAP-1) also known as amino oxidase copper containing 3 (AOC3) is a pro-inflammatory and versatile molecule with adhesive and enzymatic properties. VAP-1 is a primary amine oxidase belonging to the semicarbazide-sensitive amine oxidase (SSAO) family, which catalyzes the oxidation of primary amines leading to the production of ammonium, formaldehyde, methylglyoxal, and hydrogen peroxide. VAP-1 is mainly expressed by endothelial cells, smooth muscle cells, adipocytes and pericytes. It is involved in a repertoire of bi...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - October 6, 2022 Category: Surgery Authors: Marianna Danielli Roisin Clare Thomas Lauren Marie Quinn Bee Kang Tan Source Type: research

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