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Source: Neurology
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Total 65 results found since Jan 2013.

Oral antidiabetic drugs and dementia risk: Does treatment matter?
As the population ages, dementia grows as a public health problem. The rising life expectancy and the aging of the so-called baby boomer cohort translate to a substantial number of people reaching ages of high risk for age-related conditions like dementia. As a major cause of disability and dependency in elderly people, dementia puts social and economic burden on patients and their families and affects health care systems worldwide. In the absence of a cure, primary prevention will have the largest effect on the reduction of dementia occurrence.1 Thus, public health research should focus on the identification of modifiable...
Source: Neurology - October 30, 2017 Category: Neurology Authors: Fink, A., Haenisch, B. Tags: All Cognitive Disorders/Dementia, All epidemiology EDITORIALS Source Type: research

Adolescent weight gain confers long-term increased stroke risk: Weighty matters
Adult obesity has been consistently associated with risk of total, ischemic, and hemorrhagic stroke1–3; however, the degree to which change in weight and body mass index (BMI) during late childhood and adolescence affects adult risk of stroke has remained uncertain. Understanding this relationship is of particular importance given the rising obesity epidemic during childhood and adolescence.
Source: Neurology - July 24, 2017 Category: Neurology Authors: Rexrode, K. M., Kimm, S. Y. S. Tags: All Pediatric, Adolescence, Cohort studies, Infarction, Intracerebral hemorrhage EDITORIALS Source Type: research

Insulin resistance among obese middle-aged is associated with decreased cerebrovascular reactivity
Conclusions: IR is associated with impaired CVR; the relationship appears to be driven by the degree of IR and not by obesity. These rarely reported results suggest that early forms of cerebrovascular dysfunction exist among obese middle-aged individuals with significant IR but without type 2 diabetes mellitus. These functional vascular abnormalities may help explain the associations among IR, diabetes, and dementia, and suggest that interventions aiming to improve IR or CVR may help prevent cognitive decline later in life.
Source: Neurology - July 17, 2017 Category: Neurology Authors: Frosch, O. H., Yau, P. L., Osorio, R. S., Rusinek, H., Storey, P., Convit, A. Tags: MRI, All Cerebrovascular disease/Stroke ARTICLE Source Type: research

Rapid transitions in the epidemiology of stroke and its risk factors in China from 2002 to 2013
Conclusions: In 2002–2013, the incidence of stroke in China increased rapidly. Combined with a high prevalence, a trend toward a younger age, and stable mortality, this finding suggests that additional clinical and behavioral interventions for metabolic and lifestyle risk factors are necessary to prevent stroke, particularly in certain populations.
Source: Neurology - July 3, 2017 Category: Neurology Authors: Guan, T., Ma, J., Li, M., Xue, T., Lan, Z., Guo, J., Shen, Y., Chao, B., Tian, G., Zhang, Q., Wang, L., Liu, Y. Tags: All Cerebrovascular disease/Stroke, Prevalence studies, Incidence studies, Risk factors in epidemiology ARTICLE Source Type: research

Body mass index and outcome after revascularization for symptomatic carotid artery stenosis
Conclusions: BMI is not associated with periprocedural risk of stroke or death; however, BMI 25–<30 is associated with lower postprocedural risk than BMI 20–<25. These observations were similar for CAS and CEA.
Source: Neurology - May 22, 2017 Category: Neurology Authors: Volkers, E. J., Greving, J. P., Hendrikse, J., Algra, A., Kappelle, L. J., Becquemin, J.-P., Bonati, L. H., Brott, T. G., Bulbulia, R., Calvet, D., Eckstein, H.-H., Fraedrich, G., Gregson, J., Halliday, A., Howard, G., Jansen, O., Roubin, G. S., Brown, M. Tags: Stroke prevention, Clinical trials Systematic review/meta analysis, Risk factors in epidemiology, Infarction ARTICLE Source Type: research

Physical activity, but not body mass index, predicts less disability before and after stroke
Conclusions: Physical inactivity predicts a higher risk of being dependent both before and after stroke.
Source: Neurology - May 1, 2017 Category: Neurology Authors: Rist, P. M., Capistrant, B. D., Mayeda, E. R., Liu, S. Y., Glymour, M. M. Tags: All Cerebrovascular disease/Stroke, Cohort studies, Risk factors in epidemiology ARTICLE Source Type: research

Stroke system of care in Louisiana (P6.261)
Conclusions:After LERN’s recognition of stroke facility designations, implementation of education for stroke providers and quality improvement process, the proportion of patients treated with IV tPA has doubled in the state of Louisiana over a 5-year period. LERN’s Statewide stroke system of care has been instrumental in facilitating this progress.Disclosure: Dr. Navalkele has nothing to disclose. Dr. Hargrove has nothing to disclose. Dr. Chernyshev has nothing to disclose. Dr. Acosta has nothing to disclose. Dr. DeAlvare has nothing to disclose. Dr. Hidalgo has nothing to disclose. Dr. El Khoury has nothing to...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Navalkele, D., Hargrove, P., Chernyshev, O., Acosta, J., DeAlvare, L., Hidalgo, G., El Khoury, R., Martin-Schild, S. Tags: Cerebrovascular Disease Systems of Care and Health Policy Source Type: research

Obstructive Sleep Apnea is Associated with Improved Ischemic Stroke Outcomes (P4.312)
Conclusions:Among inpatients diagnosed with IS, OSA was associated with lower odds of death and poor discharge status. Consistent with animal studies, ischemic preconditioning could be a mechanism by which OSA leads to better outcomes after stroke in humans.Disclosure: Dr. Low has nothing to disclose. Dr. Elkind has received personal compensation in an editorial capacity for Neurology.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Low, D., Elkind, M. Tags: Neuroepidemiology: Cerebrovascular Disease II Source Type: research

Achieving better detection of vascular risk factors for stroke prevention (P4.062)
Conclusions:The concept of vital station is a useful means of detecting vascular risk factor before appearance of noticeable symptoms and thus offers the benefit of being able to treat the disease much earlier which can lead to reduction of disease burden & economic losses and thus offers better health outcome.Disclosure: Dr. Mehndiratta has nothing to disclose. Dr. Wadhai has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Mehndiratta, M. M., Wadhai, S. Tags: General Neurology: Vascular Neurology Source Type: research

Elevated Serum Creatinine Predicts Higher Mortality in Stroke Patients (P3.254)
Conclusions:Abnormal renal function at the time of stroke admission was noted in older male patients with hypertension and reduced pre-stroke eGFR. High stroke admission Cr level was a significant predictor of mortality. High risk patients needs to be identified and aggressively treated to reduce mortality risks.Disclosure: Dr. Ibrahim has nothing to disclose. Dr. Rayyis has nothing to disclose. Dr. Almekhlafi has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Ibrahim, B., Rayyis, L., Almekhlafi, M. Tags: Cerebrovascular Disease Epidemiology Source Type: research

Does Body Mass Index Impact the Outcome of Stroke Patients Who Received Intravenous Thrombolysis (P3.080)
Conclusions:BMI was not associated with functional outcome and rate of sICH in AIS patients treated with IVT.Disclosure: Dr. Zambrano Espinoza has nothing to disclose. Dr. Vaughn has nothing to disclose. Dr. Crumlish has nothing to disclose. Dr. Deline has nothing to disclose. Dr. Ching has nothing to disclose. Dr. Sawyer has nothing to disclose. Dr. Mowla has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Espinoza, M. Z., Vaughn, C., Crumlish, A., Deline, C., Ching, M., Sawyer, R. N., Mowla, A. Tags: Cerebrovascular Disease and Interventional Neurology ePoster Session Source Type: research

Body mass index and stroke in UK women: "Obesity paradox" revisited
Obesity is a major risk factor for stroke. However, several studies have reported a protective effect of obesity on stroke, particularly after a prior cardiovascular event, a phenomenon described as the "obesity paradox" or "reverse epidemiology."1 No convincing biological evidence explains this paradox. The evidence that increased body mass index (BMI) increases risk for ischemic stroke in Western and Asian populations is strong, but the relationship with hemorrhagic stroke remains less established.
Source: Neurology - October 2, 2016 Category: Neurology Authors: Rexrode, K., Rundek, T. Tags: All Cerebrovascular disease/Stroke, Cohort studies, Risk factors in epidemiology, Intracerebral hemorrhage, Subarachnoid hemorrhage EDITORIALS Source Type: research

Women Had Worse Stroke Outcome (P1.217)
Conclusion: in our cohort women have worst post-stroke outcome, even though they have higher burden of vascular risk factors they have lower prevalence of vascular disease in other vascular beds previous to stroke. This difference persists after adjusting by age, raising the possibility of specific gender risk factors influencing on ischemic stroke outcomes.Disclosure: Dr. Zurru has nothing to disclose. Dr. Colla Machado has nothing to disclose. Dr. Alonzo has nothing to disclose. Dr. Brescacin has nothing to disclose. Dr. Luzzi has nothing to disclose. Dr. Pigretti has nothing to disclose. Dr. Balian has nothing to disclo...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Zurru, M., Colla Machado, P., Alonzo, C., Brescacin, L., Luzzi, A., Pigretti, S., Balian, N., Waisman, G., Cristiano, E. Tags: Re-admission and Stroke Outcomes Source Type: research

Disparity in Decreased Age and Increased Incidence of Stroke in a Low-Income Chinese Population (P1.108)
Conclusions:Two disparities, which including decreased mean age of stroke onset and increased incidence, and decreased mean age of stroke onset and increased life expectancy were found in a low-income Chinese population, especially in men. These findings imply that stroke burden will continue to increase in China if the risk factors remain unchecked. Disclosure: Dr. Wang has nothing to disclose. Dr. Yang has nothing to disclose. Dr. An has nothing to disclose. Dr. Li has nothing to disclose. Dr. Zhao has nothing to disclose. Dr. Gu has nothing to disclose. Dr. Zhan has nothing to disclose. Dr. Bai has nothing to disclo...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Wang, J., Yang, L., An, Z., Li, B., Zhao, W., Gu, H., Zhan, C., Bai, L., Tu, J., Ning, X. Tags: Neuroepidemiology: Cerebrovascular Disease Source Type: research

Why Delay the Control of Modifiable Vascular Risk Factors (MVRF) Until the Occurrence of an Ischemic Stroke (iStroke)? (P1.180)
Conclusions: We found that the management of MVRF increases after the first ischemic event and this improves the early prognosis of iStroke (Rankin-based disability). It is important to improve the management of these factors in the setting of primary prevention.Disclosure: Dr. Pagano Ajolfi has nothing to disclose. Dr. Sanz has nothing to disclose. Dr. Alfonso has nothing to disclose. Dr. Seijas has nothing to disclose. Dr. Arrébola has nothing to disclose. Dr. Giannaula has received personal compensation for activities with Boehringer Ingelheim.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Pagano Ajolfi, S., Sanz, P., Alfonso, A., Seijas, M., Arrebola, M., Giannaula, R. Tags: Cerebrovascular Disease: Risk Factors and Prevention Source Type: research