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Differences in Ischaemic and Haemorrhagic Strokes in Sri Lanka: 7-year data from the Ragama Stroke Registry (P1.092)
CONCLUSIONS:Clinical and risk factor profiles were different between ICH and IS patients. Stroke severity and functional disability were higher among ICH patients. Study Supported by:Ragama Stroke Registry has been partly supported by research grants from the University of Kelaniya and Research Institute, International Medical Centre of Japan.Disclosure: Dr. Ranawaka has nothing to disclose. Dr. Peiris has nothing to disclose. Dr. Thirumavalavan has nothing to disclose. Dr. Premawansa has nothing to disclose. Dr. Kasthuriratne has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Ranawaka, U., Peiris, A., Thirumavalavan, K., Premawansa, G., Kasthuriratne, A. Tags: Neuroepidemiology: Cerebrovascular Disease, Critical Care, Epilepsy, Child Neurology, and Sleep Source Type: research

Predictors Of Early Mortality And Bad Outcome In Ischemic Stroke (P3.072)
Conclusion: identifying predictors of early mortality or post-stroke disability is mandatory in order to recognize opportunities of improvement and develop strategies for clinical care in this specific subgroup of patients. A multidisciplinary approach is essential to reduce clinical complications and to improve follow up after the hospitalization period.Disclosure: Dr. Luzzi has nothing to disclose. Dr. Zurru has nothing to disclose. Dr. Alonzo has nothing to disclose. Dr. Brescacin has nothing to disclose. Dr. Pigretti has nothing to disclose. Dr. Camera has nothing to disclose. Dr. Colla Machado has nothing to disclose....
Source: Neurology - April 8, 2015 Category: Neurology Authors: Luzzi, A., Zurru, M., Alonzo, C., Brescacin, L., Pigretti, S., Camera, L., Colla Machado, P., Waisman, G., Cristiano, E. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Outcome Source Type: research

Functional and cognitive prognosis in Young Stroke. (P5.169)
CONCLUSIONS: The first assessment of stroke young patients has high prognostic value in the functional and cognitive aspects.Disclosure: Dr. Martinez has nothing to disclose. Dr. Calderon has nothing to disclose. Dr. Amaya has nothing to disclose. Dr. Guerrero has nothing to disclose. Dr. Carrera has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Martinez, M., Calderon, A., Amaya, L., Guerrero, J., Carrera, R. Tags: Cerebrovascular Disease and Interventional Neurology: Recovery and Rehabilitation Source Type: research

Body Weight and Survival after Stroke: Exploring the "Obesity Paradox" in the Framingham Study (S5.005)
CONCLUSIONS: In the Framingham sample, obesity did not impact overall risk of mortality after stroke, controlling for age and sex. However, obesity or overweight in men or overweight under age 70 did appear to have a borderline protective effect on survival. These findings merit further validation and exploration.Disclosure: Dr. Aparicio has nothing to disclose. Dr. Himali has nothing to disclose. Dr. Beiser has nothing to disclose. Dr. Kase has nothing to disclose. Dr. Wolf has nothing to disclose. Dr. Seshadri has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Aparicio, H. J., Himali, J., Beiser, A., Kase, C., Wolf, P., Seshadri, S. Tags: Cerebrovascular Disease and Interventional Neurology: Recovery and Outcome Source Type: research

Effect of weight loss surgery on cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke in overweight and obese post-menopausal women (P1.071)
Conclusions: We did not observe any significant effect of weight loss surgery on reduction of cardiovascular endpoint of death, nonfatal myocardial infarction, or nonfatal stroke.Disclosure: Dr. Saeed has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Saeed, O., Malik, A., Qureshi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Epidemiology Source Type: research

Body Mass Index and Stroke Subtype in a Young Adult Stroke Population (P7.126)
CONCLUSIONS: In our group of young adult stroke patients, we found the highest BMI in the group with intracranial atherosclerosis. Although this group represented a small number of patients, this young adult population is at increased risk for future strokes. It is important to educate them on lifestyle modifications such as weight loss and exercise in addition to the treatment of hypertension, diabetes mellitus and hyperlipidemia.Disclosure: Dr. Youn has nothing to disclose. Dr. Aung has nothing to disclose. Dr. Afrasiabi has nothing to disclose. Dr. Clark has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Youn, J., Aung, T., Afrasiabi, M., Clark, J. Tags: Cerebrovascular Disease and Interventional Neurology: Stroke in Young Source Type: research

Quality Assessment of Vascular Disease Prevention Practices in High Risk Urban Women (P7.139)
CONCLUSIONS: Despite their proven value for secondary prevention, antiplatelet therapy and statins were underutilized in women with prior stroke or TIA. Strategies to intensify vascular disease prevention in high risk urban women and particularly women under 70 are needed. Study Supported by:Pfizer Disclosure: Dr. Chaturvedi has received personal compensation for activities with Genentech, Inc., Abbott Vascular, Boehringer-Ingelheim, WL Gore, and Merck. Dr. Chaturvedi has received personal compensation in an editorial capacity for NEJM Journal Watch Neurology. Dr. Pieper has nothing to disclose. Dr. Levine ha...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Chaturvedi, S., Pieper, D., Levine, D., Thati, N., Madhavan, R., Mateo, M., Cardozo, L., Lepczyk, M. Tags: Cerebrovascular Disease and Interventional Neurology: Race, Ethnicity, and Stroke Source Type: research

Comparison of major modifiable stroke risk factors associated with lacunar strokes in anterior and posterior circulation in multiethnic cohort (P7.143)
CONCLUSIONS: Hypertriglyceridemia may be associated with posterior circulation SVD. In the setting of the obesity epidemic, hypertriglyceridemia prevalence is increasing; therefore, we might expect a concomitant increase in the incidence of posterior circulation strokes.Disclosure: Dr. Bulic has nothing to disclose. Dr. Valle has nothing to disclose. Dr. Towfighi has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Bulic, S., Valle, N., Towfighi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Race, Ethnicity, and Stroke Source Type: research

Are there Different Rates of Acute Stroke Risk Factors in the South Texas Mexican American population? (P7.146)
CONCLUSION: In the South Texas Mexican American AIS population, there is greater then a three-fold higher prevalence of hypertension, diabetes and CHF compared with Hispanics/Latinos in the US. AFIB and CHF are significant predictors of poor outcome in this unique population.Disclosure: Dr. Tekle has nothing to disclose. Dr. Hassan has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Jones-Fullingim has nothing to disclose. Dr. Sanchez has nothing to disclose. Dr. Jani has nothing to disclose. Dr. Sanchez has nothing to disclose. Dr. Abantao has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Tekle, W., Hassan, A., Malik, A., Jones-Fullingim, L., Sanchez, C., Jani, V., Sanchez, O., Abantao, E., Qureshi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Race, Ethnicity, and Stroke Source Type: research

Increasing stroke incidence and prevalence of risk factors in a low-income Chinese population
Conclusions: The incidence of stroke in rural China increased rapidly, particularly among middle-aged adults, along with a concurrent increase in risk factor prevalence. These findings suggest that without controlling these risk factors, stroke incidence will continue to increase over future decades in China.
Source: Neurology - January 26, 2015 Category: Neurology Authors: Wang, J., An, Z., Li, B., Yang, L., Tu, J., Gu, H., Zhan, C., Liu, B., Su, T.-C., Ning, X. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Incidence studies, Risk factors in epidemiology ARTICLE Source Type: research

Adult stroke risk after growth hormone treatment in childhood: First do no harm
This report has been much anticipated by the endocrinology community because it extends and clarifies findings in a 2012 study showing increased mortality in adults treated in childhood with GH from the prospective European cohort study—the Safety and Appropriateness of Growth Hormone Treatments in Europe (SAGhE).3
Source: Neurology - August 25, 2014 Category: Neurology Authors: Ichord, R. N. Tags: Stroke in young adults, All Cerebrovascular disease/Stroke, Patient safety, Cohort studies EDITORIALS Source Type: research

Interleukin-6 and C-reactive protein as predictors of cognitive decline in late midlife
Conclusions: Elevated IL-6 but not CRP in midlife predicts cognitive decline; the combined cross-sectional and longitudinal effects over the 10-year observation period corresponded to an age effect of 3.9 years.
Source: Neurology - August 4, 2014 Category: Neurology Authors: Singh-Manoux, A., Dugravot, A., Brunner, E., Kumari, M., Shipley, M., Elbaz, A., Kivimaki, M. Tags: All Cognitive Disorders/Dementia, Cognitive aging, Risk factors in epidemiology ARTICLE Source Type: research

Comment: Intracerebral hemorrhage incidence declines, but it is still highly fatal
Overall stroke mortality has declined over the last decades—a welcome trend.1 However, recent trends in intracerebral hemorrhage (ICH) incidence are not as clear. On the one hand, there has been increasingly good population control of hypertension; on the other hand, there is increasing use of anticoagulants and antithrombotic drugs, an epidemic of obesity and diabetes, and changing racial and ethnic demographics.
Source: Neurology - June 16, 2014 Category: Neurology Authors: Smith, E. E. Tags: Cohort studies, Incidence studies, Natural history studies (prognosis), Intracerebral hemorrhage ARTICLE Source Type: research

Multimorbidity and the risk of restless legs syndrome in 2 prospective cohort studies
Conclusions: Multimorbidity was a strong risk factor for RLS in these 2 population-based cohort studies. The results support the hypothesis that cumulative disease burden is more important than the presence of a specific single disease in the pathophysiology of RLS.
Source: Neurology - June 2, 2014 Category: Neurology Authors: Szentkiralyi, A., Volzke, H., Hoffmann, W., Trenkwalder, C., Berger, K. Tags: Restless legs syndrome, Cohort studies, Risk factors in epidemiology ARTICLE Source Type: research

Stroke Risk Factors, Subtypes, and 30-Day Case Fatality in Abuja, Nigeria (P1.121)
CONCLUSIONS: Although hypertension, obesity, diabetes mellitus, and atrial fibrillation were important stroke risk factors, in many patients, these were detected only after a stroke. While the commonest stroke subtype was cerebral infarction, observed in almost two-third of patients, SAH was associated with the highest case-fatality rate at 30 days of 44.4%. Larger population-based studies are planned.Study Supported by: nilDisclosure: Dr. Bwala has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Bwala, S. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Subtype Source Type: research

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