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Improvement of peripheral artery disease with Sildenafil and Bosentan combined therapy in a patient with limited cutaneous systemic sclerosis: A case report
We report a case of a 48-year-old Black woman, who developed severe left limb claudication and walking limitation following a left femoropopliteal bypass occlusion in 2014. She was a heavy smoker and had a history of right middle cerebral artery ischemic stroke and bilateral Raynaud phenomenon. Diagnoses: According to the American College of Rheumatology/European League Against Rheumatism-2013 criteria, diagnosis of limited cutaneous SSc was retained with macrovascular lesions. She was referred for investigation of left limb claudication on treadmill using transcutaneous oxygen pressure measurement during exercise to argu...
Source: Medicine - June 1, 2017 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Lessons From the Heart Troponin Elevations in Patients With Established Peripheral Artery Disease ∗
The prevalence of peripheral artery disease (PAD) is estimated to be approximately 4.3% among U.S. adults older than 40 years of age and close to 15% in those 75 years and older (1). Patients with established PAD have a high probability of atherosclerosis in other vascular beds (2) and are at increased risk for myocardial infarction, stroke, and death, as well as limb ischemic events that lead to peripheral revascularization procedures and amputations (3). Data from the international REACH (REduction of Atherothrombosis for Continued Health) registry indicate that the annual risk of cardiovascular death, myocardial infarct...
Source: Journal of the American College of Cardiology: Cardiovascular Imaging - April 14, 2014 Category: Radiology Source Type: research