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Condition: Brain Tumor
Nutrition: Chloride

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Total 2 results found since Jan 2013.

Orexin-A alleviates astrocytic apoptosis and inflammation via Inhibiting OX1R-mediated NF- κB and MAPK signaling pathways in cerebral ischemia/reperfusion injury
Biochim Biophys Acta Mol Basis Dis. 2021 Aug 3:166230. doi: 10.1016/j.bbadis.2021.166230. Online ahead of print.ABSTRACTOrexin-A (OXA) is a neuropeptide with neuroprotective effect by reducing cerebral ischemia/reperfusion injury (CIRI). Inflammation and apoptosis mediated by astrocyte activation are the key pathological mechanisms for CIRI. We thus attempted to confirm neuroprotective effects of OXA on astrocytic inflammation and apoptosis in CIRI and clarify the relative mechanisms. A middle cerebral artery occlusion and reperfusion (MCAO/R) rat model and U251 glioma cells model subjected to oxygen glucose deprivation an...
Source: Biochimica et Biophysica Acta - August 6, 2021 Category: Biochemistry Authors: Dandan Xu Tingting Kong Ziqi Shao Minghui Liu Rumin Zhang Shengnan Zhang Qingxia Kong Jing Chen Baohua Cheng Chunmei Wang Source Type: research