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Steroid refractory giant cell arteritis with bilateral vertebral artery occlusion and middle cerebellar peduncle infarction.
We describe a 72-year-old male who developed bilateral vertebral artery occlusion and middle cerebellar peduncle infarction secondary to giant cell arteritis in spite of high-dose steroids. PMID: 31188339 [PubMed - in process]
Source: Journal of the Royal College of Physicians of Edinburgh - June 13, 2019 Category: General Medicine Tags: J R Coll Physicians Edinb Source Type: research

The tos study control data: how well do neurology in-patients recall being examined and does it matter?
Conclusions Although recall bias is a potential problem for the TOS score, this control data indicates that it should not be seen as a significant issue and does not negate the findings of our previous data collection that large numbers of in–patients with neurological problems are not been appropriately examined. TOS scores provide a method of quantifying the thoroughness of neurological examination and we are at present in the process of organising a multicentre study in six countries using TOS scores to establish how widespread this problem is globally.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Mulla, A., Appleton, J., Nicholl, D. Tags: Headache (including migraine), Stroke Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research

The medical research council neuromuscular centre for translational research mitochondrial disease patient cohort study uk: from conceptualisation to utilisation
Conclusion For the first time in the UK it is possible to access a large cohort of well–characterised patients with mitochondrial disease. The cohort provides objective data on mitochondrial disease progression, in children and adults, allowing evidence–based guidelines to be developed, and prognostic advice to be provided to patients and families. There is a vast amount of data still to be analysed that will provide systematic evidence and allow the development of disease prevention strategies.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Nesbitt, V., Pitceathly, R., Cockell, S., Poulton, J., Rahman, S., Hanna, M., Taylor, R., Chinnery, P., Turnbull, D., McFarland, R. Tags: Genetics, Epilepsy and seizures, Headache (including migraine), Muscle disease, Neuromuscular disease, Stroke, Musculoskeletal syndromes Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 Oc Source Type: research

Sensitivity of transcranial doppler and transoesophageal echocardiography for the detection of patent foramen ovale in cryptogenic stroke
Conclusions TCD with bubble test is sensitive and specific for the detection of right–to–left shunts due to PFO confirmed at right heart catheterisation. In this population, TOE had low sensitivity for RLS. There was no difference in physical PFO size between TOE positive and negative patients.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Morhij, D., Dani, K., Stewart Hillis, W., Muir, K. Tags: Headache (including migraine), Neuroimaging, Stroke, Hypertension, Ischaemic heart disease, Radiology, Radiology (diagnostics) Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research

Spontaneous intracranial hypotension: clinical features in eight cases
Conclusions SIH is an under–recognised but fairly common disorder. Clinical examination is usually normal, and confirmation of the diagnosis requires investigations and treatment not used routinely in the management of headache. Investigations, including contrast–enhanced neuroimaging, are often normal in the acute or chronic phase. Clinical history taking skills are therefore paramount in recognising this disorder. Characteristic features include a new daily persistent headache in a cranio–cervical distribution, with often bizarre sounding additional symptoms. Our results challenge the prevailing notions...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Anderson, J., Corkill, R. Tags: Headache (including migraine), Pain (neurology), Stroke, Ear, nose and throat/otolaryngology Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research

Staring you in the face! sturge-weber syndrome is a spectrum disorder and late presentation is possible
A 52 year old man with a four year history of migraine with aura presented to hospital with a severe right sided headache and prolonged episode of left sided sensory and motor disturbance. Examination revealed left homonymous hemianopia, sensory inattention and hemiparesis (3/5). Reflexes were symmetrical and plantars downing. He had a facial port wine stain in a V1 distribution on the right. Unenhanced CT scan was normal. Migrainous infarction was the working diagnosis and he was commenced on aspirin. Two days later he experienced intermittent episodes of left face and arm twitching consistent with focal motor seizures, t...
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Cosgrove, J., Hassan, A. Tags: Genetics, Drugs: CNS (not psychiatric), Epilepsy and seizures, Headache (including migraine), Pain (neurology), Stroke, Radiology, Radiology (diagnostics) Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP) Source Type: research

Stroke risk after a first late-onset migraine-like transient neurological attack (tna): oxford vascular study tna cohort
Conclusions The short and long–term risks of stroke in patients with a first migraine–like TNA are significantly lower than after a definite TIA. The trend towards a higher stroke risk than the underlying population rate is similar to that seen in studies of individuals with clinically–definite migraine with aura.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Tuna, M. A., Mehta, Z., Rothwell, P. M. Tags: Headache (including migraine), Stroke Association of British Neurologists (ABN) joint meeting with the Royal College of Physicians (RCP), London, 23-24 October 2013 Source Type: research