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Source: Brain and Language
Condition: Aphasia

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Total 57 results found since Jan 2013.

'Moderate global aphasia': A generalized decline of language processing caused by glioma surgery but not stroke
Brain Lang. 2021 Dec 6;224:105057. doi: 10.1016/j.bandl.2021.105057. Online ahead of print.ABSTRACTUnlike stroke, neurosurgical removal of left-hemisphere gliomas acts upon a reorganized language network and involves brain areas rarely damaged by stroke. We addressed whether this causes the profiles of neurosurgery- and stroke-induced language impairments to be distinct. K-means clustering of language assessment data (neurosurgery cohort: N = 88, stroke cohort: N = 95) identified similar profiles in both cohorts. But critically, a cluster of individuals with specific phonological deficits was only evident in the stroke but...
Source: Brain and Language - December 9, 2021 Category: Neurology Authors: Andrey Zyryanov Ekaterina Stupina Elizaveta Gordeyeva Olga Buivolova Evdokiia Novozhilova Yulia Akinina Oleg Bronov Natalia Gronskaya Galina Gunenko Ekaterina Iskra Elena Ivanova Anton Kalinovskiy Evgenii Kliuev Dmitry Kopachev Elena Kremneva Oksana Kryuc Source Type: research

Cohesive and coherent connected speech deficits in mild stroke.
This study aims to investigate (1) whether stroke patients without aphasia exhibit impairments in cohesion and coherence in connected speech, and (2) the role of attention and executive functions in the production of connected speech. Eighteen stroke patients (8 right hemisphere stroke [RHS]; 6 left [LHS]) and 21 healthy controls completed two self-generated narrative tasks to elicit connected speech. A multi-level analysis of within and between-sentence processing ability was conducted. Cohesion and coherence impairments were found in the stroke group, particularly RHS patients, relative to controls. In the whole stroke g...
Source: Brain and Language - January 19, 2017 Category: Neurology Authors: Barker MS, Young B, Robinson GA Tags: Brain Lang Source Type: research

The neuroanatomy of pure apraxia of speech in stroke.
Abstract The left insula or Broca's area have been proposed as the neuroanatomical correlate for apraxia of speech (AOS) based on studies of patients with both AOS and aphasia due to stroke. Studies of neurodegenerative AOS suggest the premotor area and the supplementary motor areas as the anatomical correlates. The study objective was to determine the common infarction area in patients with pure AOS due to stroke. Patients with AOS and no or equivocal aphasia due to ischemic stroke were identified through a pre-existing database. Seven subjects were identified. Five had pure AOS, and two had equivocal aphasia. MR...
Source: Brain and Language - February 17, 2014 Category: Neurology Authors: Graff-Radford J, Jones DT, Strand EA, Rabinstein AA, Duffy JR, Josephs KA Tags: Brain Lang Source Type: research

Treatment of dysphasia with rTMS and language therapy after childhood stroke: Multimodal imaging of plastic change.
Abstract Expressive dysphasia accompanies left inferior frontal gyrus (IFG/Broca) injury. Recovery may relate to interhemispheric balance with homologous, contralesional IFG but is unexplored in children. We evaluated effects of inhibitory rTMS to contralesional IFG combined with intensive speech therapy (SLT). A 15year-old, right-handed male incurred a left middle cerebral artery stroke. After 30months, severe non-fluent dysphasia impacted quality of life. Language networks, neuronal metabolism and white matter pathways were explored using MRI. Language function was measured longitudinally. An intensive SLT progr...
Source: Brain and Language - June 1, 2016 Category: Neurology Authors: Carlson HL, Jadavji Z, Mineyko A, Damji O, Hodge J, Saunders J, Hererro M, Nowak M, Patzelt R, Mazur-Mosiewicz A, MacMaster FP, Kirton A Tags: Brain Lang Source Type: research

Affective speech prosody perception and production in stroke patients with left-hemispheric damage and healthy controls.
CONCLUSION: Individuals with left-hemisphere damage after stroke have impaired affective prosodic perception and production that may be associated with reduced quality of life. PMID: 28013040 [PubMed - as supplied by publisher]
Source: Brain and Language - December 21, 2016 Category: Neurology Authors: Leung JH, Purdy SC, Tippett LJ, Leão SH Tags: Brain Lang Source Type: research

Continuous theta burst stimulation over right pars triangularis facilitates naming abilities in chronic post-stroke aphasia by enhancing phonological access.
CONCLUSION: CTBS of the rPTr enhances naming by facilitating phonological access during word retrieval, indicating that individuals whose naming impairment is localized to this stage of processing may be most likely to benefit from this rTMS approach. PMID: 30870740 [PubMed - as supplied by publisher]
Source: Brain and Language - March 10, 2019 Category: Neurology Authors: Harvey DY, Mass JA, Shah-Basak PP, Wurzman R, Faseyitan O, Sacchetti DL, DeLoretta L, Hamilton RH Tags: Brain Lang Source Type: research

Intensive therapy induces contralateral white matter changes in chronic stroke patients with Broca's aphasia.
Abstract Using a pre-post design, eleven chronic stroke patients with large left hemisphere lesions and nonfluent aphasia underwent diffusion tensor imaging and language testing before and after receiving 15weeks of an intensive intonation-based speech therapy. This treated patient group was compared to an untreated patient group (n=9) scanned twice over a similar time period. Our results showed that the treated group, but not the untreated group, had reductions in fractional anisotropy in the white matter underlying the right inferior frontal gyrus (IFG, pars opercularis and pars triangularis), the right posterio...
Source: Brain and Language - July 17, 2014 Category: Neurology Authors: Wan CY, Zheng X, Marchina S, Norton A, Schlaug G Tags: Brain Lang Source Type: research

Bilateral brain reorganization with memantine and constraint-induced aphasia therapy in chronic post-stroke aphasia: An ERP study.
Abstract Changes in ERP (P100 and N400) and root mean square (RMS) were obtained during a silent reading task in 28 patients with chronic post-stroke aphasia in a randomized, double-blind, placebo-controlled trial of both memantine and constraint-induced aphasia therapy (CIAT). Participants received memantine/placebo alone (weeks 0-16), followed by drug treatment combined with CIAT (weeks 16-18), and then memantine/placebo alone (weeks 18-20). ERP/RMS values (week 16) decreased more in the memantine group than in the placebo group. During CIAT application (weeks 16-18), improvements in aphasia severity and ERP/RMS...
Source: Brain and Language - April 28, 2015 Category: Neurology Authors: Barbancho MA, Berthier ML, Navas-Sánchez P, Dávila G, Green-Heredia C, García-Alberca JM, Ruiz-Cruces R, López-González MV, Dawid-Milner MS, Pulvermüller F, Lara JP Tags: Brain Lang Source Type: research

Tracking reorganization of large-scale effective connectivity in aphasia following right hemisphere stroke.
Abstract In this paper we demonstrate the application of new effective connectivity analyses to characterize changing patterns of task-related directed interaction in large (25-55 node) cortical networks following the onset of aphasia. The subject was a left-handed woman who became aphasic following a right-hemisphere stroke. She was tested on an auditory word-picture verification task administered one and seven months after the onset of aphasia. MEG/EEG and anatomical MRI data were used to create high spatiotemporal resolution estimates of task-related cortical activity. Effective connectivity analyses of those d...
Source: Brain and Language - March 29, 2017 Category: Neurology Authors: Gow DW, Ahlfors SP Tags: Brain Lang Source Type: research

Critical brain regions related to post-stroke aphasia severity identified by early diffusion imaging are not the same when predicting short- and long-term outcome.
CONCLUSION: Routine clinical images can be merged with atlases of anatomical connectivity to provide new insights about the relationship between the lesion location and aphasia severity. PMID: 30179751 [PubMed - as supplied by publisher]
Source: Brain and Language - September 1, 2018 Category: Neurology Authors: Zavanone C, Samson Y, Arbizu C, Dupont S, Dormont D, Rosso C Tags: Brain Lang Source Type: research

Treatment-induced neuroplasticity after anomia therapy in post-stroke aphasia: A systematic review of neuroimaging studies
Brain Lang. 2023 Aug 24;244:105300. doi: 10.1016/j.bandl.2023.105300. Online ahead of print.ABSTRACTWe systematically reviewed the literature on neural changes following anomia treatment post-stroke. We conducted electronic searches of CINAHL, Cochrane Trials, Embase, Ovid MEDLINE, MEDLINE-in-Process and PsycINFO databases; two independent raters assessed all abstracts and full texts. Accepted studies reported original data on adults with post-stroke aphasia, who received behavioural treatment for anomia, and magnetic resonance brain imaging (MRI) pre- and post-treatment. Search results yielded 2481 citations; 33 studies w...
Source: Brain and Language - August 26, 2023 Category: Neurology Authors: Tijana Simic Marie- Ève Desjardins Melody Courson Christophe Bedetti B érengère Houzé Simona Maria Brambati Source Type: research