• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

The Role of CMV Infection in Primary Lesions, Development and Clinical Expression of Atherosclerosis
J Clin Med. 2022 Jul 1;11(13):3832. doi: 10.3390/jcm11133832.ABSTRACTThe number of deaths related to cardiovascular disease is increasing every year, despite all available therapies and the aggressive campaigns for lifestyle modification and prevention of risk factors. Atherosclerosis is a complex process underlying cardiovascular disease. Cytomegalovirus (CMV) is often associated to atherosclerosis and its clinical expression such as coronary heart disease, stroke, or peripheral artery disease. CMV infection may promote acute atherosis within placentas from women with preeclampsia and it may also accelerate atherosclerosi...
Source: Atherosclerosis - July 9, 2022 Category: Cardiology Authors: Carmen Valentina Cristescu Sophie Alain Simona Maria Ru ță Source Type: research

CMV seropositivity and T‐cell senescence predict increased cardiovascular mortality in octogenarians: results from the Newcastle 85+ study
Summary Although chronic infection with cytomegalovirus (CMV) is known to drive T lymphocytes toward a senescent phenotype, it remains controversial whether and how CMV can cause coronary heart disease (CHD). To explore whether CMV seropositivity or T‐cell populations associated with immunosenescence were informative for adverse cardiovascular outcome in the very old, we prospectively analyzed peripheral blood samples from 751 octogenarians (38% males) from the Newcastle 85+ study for their power to predict survival during a 65‐month follow‐up (47.3% survival rate). CMV‐seropositive participants showed a higher pre...
Source: Aging Cell - December 22, 2015 Category: Cytology Authors: Ioakim Spyridopoulos, Carmen Martin‐Ruiz, Catharien Hilkens, Mohammad E. Yadegarfar, John Isaacs, Carol Jagger, Tom Kirkwood, Thomas Zglinicki Tags: Short Take Source Type: research