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Total 4396 results found since Jan 2013.

Major adverse cardiovascular events associated with testosterone treatment: a pharmacovigilance study of the FAERS database
Conclusion: For myocardial infarction and cardiomyopathy, TRT statistically tended to increase the risk of MACEs, while for cardiac arrhythmia, cardiac failure, and stroke, TRT demonstrated beneficial effects among the population with morbidities, such as testosterone deficiency (TD), diabetes mellitus (DM), and hypertension. MACEs were rare but led to serious outcomes including significant increase in death and disability. Since 2018, and before 2014, reports referring to TRT associated with MACEs were relatively scarce, which indicated that there might be a considerable number of cases that went unrecorded, due to neglec...
Source: Frontiers in Pharmacology - July 12, 2023 Category: Drugs & Pharmacology Source Type: research

Diabetes status and other factors as correlates of risk for thrombotic and thromboembolic events during SARS-CoV-2 infection: A nationwide retrospective case-control study using Cerner Real-World Data™
Conclusions Risk of TTE during COVID-19 illness is substantially higher in patients with diabetes. Further, risk for TTEs is higher in those with T1DM versus T2DM. Confirmation of increased diabetes-associated clotting risk in future studies may warrant incorporation of diabetes status into SARS-CoV-2 infection treatment algorithms.
Source: BMJ Open - July 9, 2023 Category: General Medicine Authors: Tallon, E. M., Gallagher, M. P., Staggs, V. S., Ferro, D., Murthy, D. B., Ebekozien, O., Kosiborod, M. N., Lind, M., Manrique-Acevedo, C., Shyu, C.-R., Clements, M. A. Tags: Open access, Diabetes and Endocrinology, COVID-19 Source Type: research

Sleep-related rhythmic movement disorder in adults - A systematic review with a case report
J Sleep Res. 2023 Jul 6:e13985. doi: 10.1111/jsr.13985. Online ahead of print.ABSTRACTSleep-related rhythmic movement disorder is characterised by stereotyped and repetitive rhythmic movements involving large muscle groups during sleep with frequencies between 0.5 and 2 Hz. Most of the published studies on sleep-related rhythmic movement disorder have focussed on children. Therefore, we performed a systematic review on this topic focussing on the adult population. The review is followed by a case report. The review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 ...
Source: Journal of Sleep Research - July 6, 2023 Category: Sleep Medicine Authors: Monika Michalek-Zrabkowska Mieszko Wieckiewicz Adam Wichniak Andrej Jenca Janka Jencova Weronika Frosztega Tomasz Wieczorek Justyna Chojdak-Lukasiewicz Monika Sluzewska-Niedzwiedz Anna Wojakowska Rafal Poreba Grzegorz Mazur Helena Martynowicz Source Type: research

A knowledge-based decision support system for inferring supportive treatment recommendations for diabetes mellitus
CONCLUSION: The results obtained are promising in demonstrating the applicability, effectiveness, and efficiency of the tool. It can ensure that necessary precautions are taken in advance by raising awareness of society against the DM risk.PMID:37393457 | DOI:10.3233/THC-230237
Source: Technology and Health Care - July 2, 2023 Category: Medical Devices Authors: Duygu Çelik Ertuğrul Ne şe Akcan Yiltan Bitirim Begum Koru Mahmut Sevince Source Type: research